Sentences with phrase «molecular studies also»

Not exact matches

Also there is evidence of molecular mechanisms in the cell membranes that can amplify small changes in the field to produce large changes in neural activity.13 On the other hand, earlier tests of Kohler's theory found that interference with electrical gradients over the cortex had no effect on behavioral measures (see note 11 for reference to these studies).

There, I got to study tuberculosis not only on the level of macroscopic bone changes as before, but also look at the molecular level and search for the pathogen's DNA.

The relationship between the two species has been studied by psychologists, anthropologists, ethnologists and also by genetic and molecular biologists.

Researchers also use X-rays to study ultrafast molecular motions.

Published in the peer - reviewed journal Systems Biology in Reproductive Medicine, the study, «Sperm RNA elements as markers of health,» from the lab of Stephen A. Krawetz, Ph.D., the Charlotte B. Failing Professor of Fetal Therapy and Diagnosis in the Wayne State Department of Obstetrics and Gynecology and Center for Molecular Medicine and Genetics, indicates that RNA found in male sperm not only shows promise as a determinant in successful live birth, it may also tell us more about the health of a child as it matures.

Published in the journal Molecular Cancer Therapeutics, the study also found that use of a second inhibitor might improve the effectiveness of these drugs by possibly preventing resistance, and it recommends that clinical trials should be designed to include a second inhibitor.

They also present evidence that the lines that led to Neanderthals and modern humans diverged nearly 1 million years ago, much earlier than studies based on molecular evidence have suggested.

The array will also study molecular clouds, the dense regions of gas and dust where stars are born.

A new study supported by the Milstein Medical Research Program at The Rockefeller University, however, has uncovered the molecular roots of skin discoloration that is often associated with psoriasis, suggesting the possibility of new treatments for pigmentation changes seen not only in psoriasis, but also in other conditions such as eczema and acne.

«Better assessment of teens» ability to concentrate could facilitate the identification of those at risk of anxiety and could also inform molecular genetic studies, which would be the logical next stage for research.»

Scholars also have demonstrated the biodiversity of modern - day African village chickens through molecular genetic studies.

«Until now, no studies have separated how resistance to these two different drug actions might work,» says Roepe, also a professor of biochemistry and cell and molecular biology and co-founder of Georgetown's Center for Infectious Disease at Georgetown University Medical Center.

But in the study being published, researchers at the Department of Cell and Molecular Biology at Karolinska Institutet present a molecular time mechanism that can help explain neuronal stem cell regulation and therefore also the occurrence of cellular diversity in tMolecular Biology at Karolinska Institutet present a molecular time mechanism that can help explain neuronal stem cell regulation and therefore also the occurrence of cellular diversity in tmolecular time mechanism that can help explain neuronal stem cell regulation and therefore also the occurrence of cellular diversity in the brain.

«Our study not only provides new molecular data that complement the work of the American team but also reveals key microanatomical facts, explains Michel Milinkovitch.

In the study, the researchers also reveal the molecular mechanism through which the protein dDsk2 binds to chromatin proteins, thus participating indirectly in the regulation of transcription.

Longo also had taken note of a 1990 study by University of Colorado molecular behavioral geneticist Thomas Johnson, who found roundworms with a mutation that blocked a growth pathway similar to that identified in the dwarf yeast, causing them, too, to have an increased life span.

The study results also attach numbers to molecular evidence documenting the importance of heritability traceable to common genetic variation in causing these five major mental illnesses.

The study, published Nov. 17 by Proceedings of the National Academy of Sciences, shows that triclosan causes liver fibrosis and cancer in laboratory mice through molecular mechanisms that are also relevant in humans.

«The work demonstrates that our methodology is accurate and also well suited to study the functionality of other enzymes at the molecular level,» says Ville Kaila.

«This study expands our molecular understanding of C2c2 to guide RNA processing and provides the first application of this novel RNase,» said Doudna, who is also a Howard Hughes Medical Institute investigator.

John Lew, associate professor in the Department of Molecular, Cellular & Developmental Biology, also participated in this study, as well as previous research that has demonstrated cinnamon extract's inhibitory effect on tau aggregation.

It also provides a unique imaging platform to rigorously study molecular therapies.»

The study, published recently online ahead of print in the journal Molecular Psychiatry, also points to several pathways as potential targets for treatment.

Terry Reed, a molecular geneticist at Indiana University School of Medicine in Indianapolis, who has also studied ADG, says that he is unsure whether SMARCAD1 is responsible for every patient who lacks fingerprints.

«We found that the same machinery that makes these tumors so aggressive also makes them vulnerable to nutrient deprivation,» said senior study author Jen - Tsan Ashley Chi, Ph.D., associate professor of molecular biology and microbiology at Duke University School of Medicine.

But they could also transplant groups of interacting genes, creating more humanlike yeast that would be useful for studying new drugs or molecular circuits that go awry in diseases.

The three Penn study authors are also participating with Cognition in a NASA effort reported earlier this year to study the molecular, physiological and psychological effects of spaceflight on the human body by comparing identical twins, evidencing the need for a comprehensive cognitive test battery for spaceflight.

The study's researchers also included: Shelly Buffington and Matthew Rasband of the Baylor College of Medicine; Jerry Lingrel of the Department of Molecular Genetics, Biochemistry, and Microbiology at the University of Cincinnati; and Hanoch Kaphzan, Akila Ramaraj, and Emanuela Santini of NYU's Center for Neural Science.

«By studying the epigenome, we also identified new pathways and molecular dependencies not apparent in previous gene expression and mutational studies,» Northcott said.

Have detected the mechanism behind the injuries Elin Sørhus has also conducted thorough studies of the genetics and the molecular biology behind the haddock larvae's injuries.

It may also lead to improved therapies to fight sleeping sickness; current medications used to combat the disease have improved over the past decade but still include an old arsenic - based drug that kills between 5 and 10 percent of the people receiving treatment, said the study's senior author Stephen Hajduk, a professor of biochemistry and molecular biology in the UGA Franklin College of Arts and Sciences.

Moreover, our previous study found that regular use of aspirin after diagnosis was associated with longer survival among the 15 % to 30 % of patients with colorectal cancer and with a mutation in phosphatidylinositol -4,5-bisphosphate 3 - kinase, catalytic subunit alpha (PIK3CA [NCBI Entrez Gene 5290]-RRB-, one of the PI3K family genes.30 Markedly improved survival associated with aspirin according to PIK3CA status was also found in an analysis within a separate clinical trial cohort.31 Further investigations for the joint effect of these genes would be helpful to better understand the underlying molecular mechanisms of aspirin, NSAIDs, and colorectal cancer.

«From our present work we hope to one day identify a specific inhibitor of endogenous TORC2 which could also find use as an effective anti-cancer agent,» concludes Taiana Oliveira, a researcher in the group of Christiane Schaffitzel at the European Laboratory of Molecular Biology, in Grenoble, France, and third co-lead author of the study.

Molecular, subcellular and cellular studies in whole animals or humans; and novel molecular, immunological or biophysical studies of hormone action are also Molecular, subcellular and cellular studies in whole animals or humans; and novel molecular, immunological or biophysical studies of hormone action are also molecular, immunological or biophysical studies of hormone action are also featured.

«We see elements of this framework of primary and secondary cell - fate determinants throughout the hematopoietic system,» said study author Harinder Singh, the Louis Block Professor of Molecular Genetics & Cell Biology and a Howard Hughes Medical Institute Investigator at the University of Chicago, «and we suspect such networks also regulate cell fate in other systems.»

We also study how molecular signaling, translational control, synaptic plasticity, and behavior are altered in mouse models of developmental disability, autism, aging, and Alzheimer's disease.

As executive secretary, he also conducted a careful scientific assessment of the rapidly evolving field of biochemistry to justify the creation of new study sections in two emerging areas, molecular and physical biochemistry.

Kriwacki also said that the paper was significant because it emphasizes the importance of the role that p53 plays in the cytosol of the cell, in addition to its role in the nucleus; his further studies are seeking to map that molecular machinery in great detail.

The latest study builds on earlier work that analyzed hydrocarbons with smaller molecular rings that have also been observed in space, including in Saturn's moon Titan — namely benzene and naphthalene.

EthoVision XT is used in a wide range of fields, mostly related to neurosciences, such as toxicology, safety pharmacology, psychopharmacology, drug discovery, molecular biology, genetics, behavioral neurosciences, but also in applied ethology, and animal welfare studies.

The study, published in Human Molecular Genetics, has shown that the majority of genes associated with Nephrotic Syndrome (NS) in humans are also pivotal in Drosophila renal function, validating transgenic flies as accurate pre-clinical models.

Studies also will allow scientists to track the molecular steps that the cell goes through as it evolves into the nerve cell, or neuron, it produces.

The statement also makes recommendations for clinical guidance and research priorities, such as optimal choice of EGFR tyrosine kinase inhibitors (TKIs), management of brain metastasis, role of re-biopsies, and use of circulating free DNA (cfDNA) for molecular studies.

But in a study published April 5 in Cell, Kevan Shokat, PhD, a professor of cellular and molecular pharmacology, and postdoctoral researcher Qi Hu, PhD, discovered that another common cancer - causing mutation in a GTPase called Gαs (or G - alpha - s) subverts the model: it doesn't just jam the switch in the «on» position, but also disconnects the switch entirely.

The findings also support using the Tff1 - knockout mouse model for in vivo studies of molecular mechanisms in gastric cancer.

«So, not only does ALMA let us identify individual molecular species in the coma, it also gives us the ability to map their locations with great sensitivity,» said Anthony Remijan, a scientist with the National Radio Astronomy Observatory, one of the organizations that operates ALMA, and a co-author of the study.

Also, as shown in our study, the surviving cycling hypoxia - selected subpopulation acquires additional molecular advantages after exposure to several cycles of hypoxia / reoxygenation.

The researchers also plan to study how exactly the hypoxia response works — how low - oxygen conditions kindle molecular efforts to protect and repair the brain.

In a new study in Molecular Cell, Halbleib and coworkers have not only worked out what part of Ire1p senses disturbances in the ER membrane in our old friend S. cerevisiae, but they may also have figured out how the protein does it.

Researchers determined the atomic structure of the MOFs and the bound molecules with X-rays at Berkeley Lab's Advanced Light Source (ALS), and they also studied the MOFs using a technique called nuclear magnetic resonance (NMR) at Berkeley Lab's Molecular Foundry.