More plaque forms and the wastes dissolve away the ligament holding the tooth in the socket, creating a periodontal pocket.
Not exact matches
Sleep deprivation also caused
more plaques to develop, while an insomnia drug reduced the amount of
plaque -
forming protein (Science, DOI: 10.1126 / science.1180962).
Nevertheless, the astrocytes must «feel» something when
plaques are
formed, as when this happens they produce
more of their characteristic protein, GFAP.
As a result, they have
more opportunity to
form the deadly
plaque associated with Alzheimer's disease.
More than 40 illnesses known as amyloid diseases — Alzheimer's, Parkinson's and rheumatoid arthritis are a few — are linked to the buildup of proteins after they have transformed from their normally folded, biologically active
forms to abnormally folded, grouped deposits called fibrils or
plaques.
This alternative therapy could be a better way to prevent
plaques from
forming because small molecules
more readily cross the blood brain barrier.
And
more direct evidence for its role in making
plaques is the fact that cells produced
more beta amyloid if they contained certain mutated
forms of nicastrin, the researchers report in the 7 September issue of Nature.
That agent, aducanumab, is designed to bind preferentially to the early clumps of amyloid as they
form plaques, and therefore may be
more useful in mild or moderate patients who are already showing signs of memory loss and other cognitive problems.
When these nutrients are not sufficient in the body, calcium will be much
more likely to end up in the arteries in the
form of
plaques.
When a person is affected with
plaque psoriasis, their skin cells have an accelerated growth with lots of premature (not fully developed) skin cells coming to the surface,
forming thick skin plaques.You can read a lot
more here about psoriasis.
Due to reduced clearance via IDE, Aβ accumulates, and the
more it accumulates, the
more prone it is to
form insoluble
plaques.
Aβ results from the normal cleavage of amyloid precursor protein (APP), but its accumulation and aggregation into
plaques represents the quintessential feature of AD.27 Aβ is found in orders of magnitude greater in AD brains than in healthy brains.28 This fact is noteworthy because lower concentrations of Aβ tend to stay soluble; higher concentrations
form plaques more readily.29
Glycation is a factor of glucose concentration exposure and time, with
more AGEs
forming upon longer exposure to higher concentrations of glucose.33 It follows that in a body that is hyperinsulinemic, and a brain that is insulin - resistant, the peripheral hyperinsulinism will inhibit the clearance of soluble Aβ by IDE, thereby causing it to remain in the extracellular space for an extended amount of time, and the functional «hyperglycemia» in the brain will provide an elevated level of glucose — the perfect storm for glycation of Aβ and its aggregation into insoluble
plaques.
They guard against heart disease by making capillaries stronger and
more flexible, while reducing the adhesion, or «stickiness,» of red blood cells, making them less likely to
form atherosclerotic
plaque.
TMAO is thought to encourage fatty
plaque deposits to
form within arteries (atherosclerosis), and therefore, the
more TMAO you have in your blood the greater your risk of heart disease might be.
Plaque and tartar that build - up on your pet's teeth can lead to bacterial infections, and gingivitis, which can progress to
more advanced
forms of periodontal disease.
The deep pockets that develop over time are the perfect location for
more plaque and tartar to
form.
The tartar will stick to the tooth surface
forming a scaffold for
more plaque accumulation.
Within the pockets that
form more plaque and tartar accumulate, and a vicious cycle has started.
But a second
form that causes patches (
plaques) or lightening - like (linear) lines of inflammation on the cat's body is said to be
more common.