Sentences with phrase «most of these alterations»

I made most of the alterations people suggested including using spelt instead of wholewheat, added toasted ground flaxseed and hemp seed.

Most of these alterations are useless, even detrimental, but occasionally a mutation may help the bacterium resist a particular drug.

Most of that alteration is thought to have happened during the earliest part of Martian history, more than 3.7 billion years ago.

Although we found that manipulating GBP2 expression accounts for most of the alterations in body size in response to decreased TOR signaling, GBP1 also appears to play a role since knocking down both peptides induces stronger size reductions.

Most of these alterations are the type of thing that only series diehards are liable to notice, although having the most current and balanced version of Guilty Gear is a good thing for everyone.

Not exact matches

Amazon is by far the most influential player when it comes to forces driving the most impactful and important alterations made in the arena of commerce and its digital transformation.

This complete alteration of meaning in a word continuously employed throughout the Book is one of the most notable evidences of the development that the Book records.

That very process of scrutiny and commendation will likely change previous understandings and attitudes, and will most likely produce commensurate alterations in their faith traditions: conversion causes not just numerical change but mental shifts as well.

The grace His Divine sacrifice brought to each one of us is truly the most important interruption of the narrative, a change to the story - line, a alteration of the eternal path we would have had to take.

This is an important qualification for a number of reasons, most obviously that if one of the justifications for engagement in interreligious polemics is that it is heuristically valuable (as are its analogues in other dimensions of the intellectual life), then obviously revision, alteration, and abandonment of passionately held religious views must be a possibility.

Men will take it as a mark of bad character rather than enlightenment if, after the most drastic alteration in personality, a man refuses responsibility for all earlier commitments.

Still, this is one of the most delicious - sounding banana bread recipes I have come across, and look forward to trying it in the future with less alterations.

I made a few alterations to the recipe when I served it — used 4 cups of low sodium organic vegetable broth instead of water, and used most of a seedless cucumber in place of the avocado.

But the most devious play of the game came when Tom Brady threw for his 400th career Touchdown and Danny Amendola cleverly gave the ball away to a fan before the game officials had time to inspect it for signs of alteration.

The alteration was willfully executed that the primary would be directed toward a chosen end that bore nothing in common with the will of most state party members.

WASHINGTON — The Senate approved the most fundamental alteration of its rules in more than a generation on Thursday, ending the minority party's ability to filibuster most presidential nominees in response to the partisan gridlock that has plagued Congress for much of the Obama administration.

The alteration was wilfully executed that the primary would be directed toward a chosen end that bore nothing in common with the will of most state party members.

Characterized by malignant alterations in the blood - forming stem cells in the bone marrow, ALL is the most common form of childhood cancer.

Church says that genome - editing techniques will remain the go - to choice for most applications that require a small number of genetic alterations, whereas genome design will be useful for specialized applications, such as recoding an entire genome to incorporate new amino acids.

Gross says that the most important processes affecting day length are changes in the weather, especially unusual variations in the strength and direction of the winds, which bring on alterations in the global circulation of the atmosphere and ocean.

But some of the most dramatic ecological alterations, such as changes in bottom - dwelling invertebrates or the loss of native clams, go unnoticed by most people.

Most research on the mechanisms of TBI has focused on neurochemical changes at the site of injury, such as metabolic alterations and ion imbalances inside neurons, he says.

The research team found that most of the change was because of alterations in rainfall that are expected to occur across the area, not because of increases in temperature.

One of the most robust alterations was observed in the JAK - STAT3 pathway and the production of serum amyloid A (SAA)-- a protein which has only recently been identified as a key player in the body's immune response.

An abnormal gene created by the fusion of ETV6 and the RUNX1 gene is one of the most common alterations in childhood ALL and is found in the leukemic cells of 20 to 25 percent of pediatric ALL.

However, he believes that both Dr. Simmons» findings concerning hippocampal volume and his study on plasma Aβ concentrations suggest that the AD - suggestive alterations begin perhaps 20 - 30 years before the onset of clinical symptoms, but most probably not earlier.

«Most previous studies have focused on using one technique at a time, even though we have evidence that there are alterations in the brain in autism in terms of structure, white - matter connectivity, and brain chemical concentrations.

A University of Colorado Cancer Center study published in the journal Oncogene used next - generation sequencing technologies to perform the most detailed DNA - based analysis to date of 25 commonly used bladder cancer cell lines, allowing researchers to match patient tumors with their closest genetic cell line match, and demonstrated genetic alterations that may make cells more or less sensitive to common therapies.

The recent development of genetically - encoded fluorescent biosensors specific to glutathione (GSH), the most abundant cellular redox buffer, has facilitated the IGB research group's discovery of distinct alterations of glutathione redox potentials in the cytosol versus mitochondria within the cell.

Give these scientists, who have proven that they can think outside the box and inside the womb, the opportunity and wherewithal to design a couple of comprehensive, multi-organ assays to detect the most sensitive alterations in embryonic and fetal development and function.

«Instead of invoking large, complicated scenarios to explain the majors shifts in molar evolution during the course of hominin origins, we found that simple adjustments and alterations to this one developmental rule can account for most of those changes,» says Alejandra Ortiz, a postdoctoral researcher at Arizona State University's Institute of Human Origins and lead author of the study.

These findings represent the most comprehensive characterization of the molecular alterations in endometrial cancers available to date.

While evidence obtained in our and other laboratories strongly suggests that H. pylori triggers a transcriptional response, epigenetic alterations and DNA damage in infected cells, most of the data supporting these findings rest on fragmentary analyses of clinical samples and cells infected in vitro.

There will be a rush of new research and development to pull in the most plausible candidate genes: competition will drive this process, because specific genetic alterations will quickly become standardized, commoditized, widely cross-licensed products.

More recently, we have focused on activating mutations of the FLT3 - RTK, since this alterations has been found to represent the single most common genetic aberration, present in up to 35 % of adolescent and adult patients with AML.

Aneuploidy (an abnormal number of chromosomes) is the most common genetic alteration in human tumors and a major cause for birth defects (Figure 4).

DNA Detectives Find Genetic Markers for Lung Cancers Most Likely to Recur Researchers at the Johns Hopkins Kimmel Cancer Center uncovered clearly recognizable genetic alterations in tumors and tissue removed from patients with early - stage lung cancers that look like good predictors of which of these cancers are more likely to recur.

Massachusetts General Hospital pathologist Bradley Bernstein has studied how alterations to chromatin drive glioblastomas, the most common form of brain tumor.

Most breast cancers contain subclonal populations, many of which harbor driver alterations, and subclonal structure is typically remodeled over time, across metastasis and as a consequence of treatment interventions.

In the last decade we have witnessed tremendous advances in our understanding of the landscape of the molecular alterations that underpin many of the most prevalent cancers, in the use of automated high - throughput platforms for high - throughput drug screens in cancer cells, in the creation of more clinically relevant cancer cell models, and lastly in the development of more useful computational approaches in the pursuit of biomarkers of drug response.

Taken together, our results, along with the data of other research teams [6], suggest that the well - documented developmental alterations observed in mice, rat, sheep and cattle after embryo IVC manipulation can probably be extended to most eutherian mammals, including humans.

Surprisingly, whether or not a gene's expression was regulated by MeCP2 did not depend on its mCG content; rather, genes with high levels of mCH tended to be most affected by alterations in MeCP2 expression.

Unlike most types of gene therapy, a longstanding approach that aims to alter only adult human tissues that die with the patient, the Crispr technique could be used to change human eggs, sperm and early embryos, and such alterations would be inherited by the patient's children.

Yoga creates these kinds of lean muscles (although you certainly will need cardio and diet alteration to help with weight loss as Yoga most likely will not provide enough calorie burn).

Joint moments measured using isometric dynamometry are often very different in one part of the joint range of motion (ROM) to another (Worrell et al. 2001), which is most likely because of alterations in both muscle force at different muscle lengths (the length - tension relationship) and because of changes in the moment arm length (Baltzopoulos & Brodie, 1989).

When you take this perspective seriously, and also come to understand the level of hybridization and genetic alterations happening to some of the most basic foods in this country, like wheat and corn, for instance, it's no wonder we're sick and it's no wonder our environment is in such trouble.

Fit-wise, I was thrilled to find that Theory's Good Wool Clean Blazer is actually one of their most petite - friendly styles, with a nice slim fit throughout the shoulders and torso, and a 3/4 style sleeve that does not require any alterations on me!

They do free alterations, but I really don't think I'll be altering these at all, especially since they'll be rolled most of the time.

I don't wear pants very often as most of the off - the - rack designs are quite long for me and I am usually too lazy to arrange for alterations.

Over the course of this third solo outing for the god of thunder, Thor will lose his allies, his freedom, those flowing golden locks, and also something more permanent, but none of these will be the most significant alteration to the character in Taika Waititi's zippy, slightly tilted, often joyfully frenzied film: Thor is finally in on his own joke.