Sentences with phrase «mouse brain nerve»

Mouse brain nerve cells (green) making a disease - causing version of the tau protein were grown in lab dishes with supporting brain cells called glia.

Not exact matches

In 1999 van Praag showed that more new nerves formed in the hippocampus — one of the key centers in the brain for memory and learning — in physically active mice than in inactive ones.

The mice were also injected with a dye that could illuminate the footprints of new nerve cell growth in the brain.

In addition, compared to mice on a regular diet, brain cells from animals in the olive oil group showed a dramatic increase in nerve cell autophagy activation, which was ultimately responsible for the reduction in levels of amyloid plaques and phosphorylated tau.

The bacteria, when injected into mice, activate a set of serotonin - releasing neurons in the brain — the same nerves targeted by Prozac.

These two MRI images show details of an adult mouse brain, including the optic nerves, the cerebral cortex, the cerebellum, and the brain stem.

It reveals specialized cells in the brains of mice dividing to create newborn nerve cells.

In contrast, the new method used on mice causes certain nerve cells to fire at a specific rhythm, generating brain waves that researchers believe may clear A-beta.

While mouse models have traditionally been used in studying the genetic disorder, Deng said the animal model is inadequate because the human brain is more complicated, and much of that complexity arises from astroglia cells, the star - shaped cells that play an important role in the physical structure of the brain as well as in the transmission of nerve impulses.

The transparency made it possible for them to identify peripheral nerves — tiny bundles of nerves that are poorly understood — and to map the spread of viruses across the mouse's blood - brain barrier, which they did by marking the virus with a fluorescent agent, injecting it into the mouse's tail and watching it spread into the brain.

They first injected a fragment of myelin protein into the brains of the test mice, causing nerve damage similar to that seen in MS patients.

The neurotransmitter acetylcholine is released by nerve cells in the brain when people or mice are under mild stress or concentrating on learning something new.

Using fluorescent antibodies designed specifically to light up the receptor in mice, the investigators observed it on vagus nerves, which serve as a main biochemical connection between airway cells and the brain.

Adult mice and other rodents sprout new nerve cells in memory - related parts of their brains.

A month after H7N7 or H3N2 infection, mice had fewer nerve cell connectors called dendritic spines on cells in the hippocampus, a brain region involved in memory.

Scientists made select nerve cells in mice's brains sensitive to light, and then used lasers to activate specific groups of those cells.

Researchers also studied the brain tissue of the infected mice under a microscope and found that the memory problems tracked with changes in nerve cells.

Studies in mice suggest that the answer may lie in the vagus nerve, which connects the brain to the abdomen.

Two kinds of mouse glial brain cells, microglia and astrocytes, making different versions of the APOE protein were grown with brain nerve cells, or neurons, that make disease - causing forms of tau.

A microscope image shows nerve cells that relay information from the ear to the brain in mice.

They also tested other chemicals known to prevent the other two forms of cellular suicide, but only CGP3466B protected mouse nerve cells in the brain from death by cocaine.

In the current study, researchers found to their surprise that most of the nerve cells in auditory cortex neurons that stimulate brain activity (excitatory) had signaled less (had «weaker» activity) when the mice expected and got a reward.

To find out, the research team examined nerve cells from mouse brains for clues.

To map how the same sense can be perceived differently in the brain, the NYU Langone team, led by postdoctoral fellow Kishore Kuchibhotla, PhD, monitored nerve circuit activity in mice when the animals expected, and did not expect, to get a water reward through a straw - like tube (that they see) after the ringing of a familiar musical note.

BRANCHING OUT In 1966, researchers thought that the branching ends of nerve cells (mouse neurons shown) might store memories in the human brain.

Mice with no GDNF in their brains displayed significantly stronger reuptake of dopamine into nerve endings.

NERVE PROTECTORS The glowing cells in this micrograph of a mouse's optic nerve help shield electrical signals passing between eyes and bNERVE PROTECTORS The glowing cells in this micrograph of a mouse's optic nerve help shield electrical signals passing between eyes and bnerve help shield electrical signals passing between eyes and brain.

But active nerve cells in newborn mouse brains can't yet make this request, and their silence leaves them hungry, scientists report June 22 in the Journal of Neuroscience.

MISS MATCH After paw stimulation, nerve cells in the brain of a 7 - day - old mice become active (top row, left), but blood doesn't show up (bottom row, left).

In both mouse and fruit fly embryos, Detlev Arendt, an evolutionary biologist at the European Molecular Biology Laboratory in Heidelberg, Germany, has found that cells involved in forming the brain and nerve cord divide into three columns of cells.

Without the gene, the mice didn't have Neuroligin - 3 in their brains, a protein that helps nerve cells communicate.

The young mice showed signs of brain deterioration as well, including inflammation and decreased birthrates of new nerve cells.

Reported in Neuron, the new method enables researchers to peer deep inside a mouse's brain and watch astrocytes» influence over nerve - cell communication in real time.

The authors also found abnormalities in the subthalamic nucleus occur earlier than in other brain regions, and that subthalamic nucleus nerve cells progressively degenerate as the mice age, mirroring the human pathology of Huntington's disease.

In lab tests, they found that the bacteria aren't as virulent when a mouse isn't eating, and they use the vagus nerve, a superhighway connecting gut to brain, to encourage eating.

Previously, Dr. Smeyne and his collaborator Dr. Stacey Schultz - Cherry in the Department of Infectious Disease at St. Jude Children's Research Hospital in Memphis, TN, showed that a deadly H5N1 strain of influenza (so - called Bird Flu) that has a high mortality rate (60 percent of those infected died from the disease) was able to infect nerve cells, travel to the brain, and cause inflammation that, the researchers showed, would later result in Parkinson's - like symptoms in mice.

But he agrees with DiCicco - Bloom that there are alternative explanations for why the mice changed their behavior — for example, «maybe bacteria are activating nerves in the gut that are communicating with the brain,» he says.

Using a two - ply of flexible, thin plastic, scientists have created novel electronic sensors that send signals to the brain tissue of mice that closely mimic the nerve messages of touch sensors in human skin.

Researchers used genetically modified mice in which the axons in the corticospinal tract, a bundle of nerves carrying signals from the brain to the spinal cord, were «stained» with fluorescent matter visible under a powerful microscope.

The drug restored in the mice normal levels of serotonin, a neurotransmitter communicating messages between nerve cells in the brain.

One of Freeman's big projects is working with collaborators to study how nerve cells in the brains of mice respond to touch.

But then Hayashi created a mouse with a mutation in a gene called PAK, which codes for an enzyme called p21 - activated kinase that helps build nerve connections in the brain.

To see what was happening in the brains of these ankyrin - G mutant mice, the researchers analyzed the cell components in inhibitory synapses connecting with pyramidal neurons, finding that two proteins known as GAT1 and GAD67 — responsible for making the neurochemical GABA that dials back nerve impulses — were at much lower levels in the synapses on pyramidal neurons in ankyrin - G mutant mice than in normal mice.

Likewise, certain brain regions of these optogenetically stimulated, post-stroke mice showed increased levels of proteins associated with heightened ability of nerve cells to alter their structural features in response to experience — for example, practice and learning.

When investigators at the Stanford University School of Medicine applied light - driven stimulation to nerve cells in the brains of mice that had suffered strokes several days earlier, the mice showed significantly greater recovery in motor ability than mice that had experienced strokes but whose brains weren't stimulated.

VIDEO: 3D images of different Sst interneurons, or type of nerve cell, in the outer shell, or cerebral cortex, of the mouse brain.

Different Sst interneurons, or type of nerve cell, in the outer shell, or cerebral cortex, of the mouse brain.

Mice exposed to low - dosage of cannabis have more links between nerve cells in the brain, compared to those who were not exposed.

Scientists used mice to study how nerve cells in thalamic reticular nucleus work during sleep and how they help the brain concentrate.

When the scientists looked in the brain of a mouse with this mutation, they found, again, that MC4R was not on the nerve cell cilia where it should go to work.