Sentences with phrase «mouse brain nerve cells»

Mouse brain nerve cells (green) making a disease - causing version of the tau protein were grown in lab dishes with supporting brain cells called glia.

Not exact matches

The mice were also injected with a dye that could illuminate the footprints of new nerve cell growth in the brain.
In addition, compared to mice on a regular diet, brain cells from animals in the olive oil group showed a dramatic increase in nerve cell autophagy activation, which was ultimately responsible for the reduction in levels of amyloid plaques and phosphorylated tau.
It reveals specialized cells in the brains of mice dividing to create newborn nerve cells.
In contrast, the new method used on mice causes certain nerve cells to fire at a specific rhythm, generating brain waves that researchers believe may clear A-beta.
While mouse models have traditionally been used in studying the genetic disorder, Deng said the animal model is inadequate because the human brain is more complicated, and much of that complexity arises from astroglia cells, the star - shaped cells that play an important role in the physical structure of the brain as well as in the transmission of nerve impulses.
The neurotransmitter acetylcholine is released by nerve cells in the brain when people or mice are under mild stress or concentrating on learning something new.
Using fluorescent antibodies designed specifically to light up the receptor in mice, the investigators observed it on vagus nerves, which serve as a main biochemical connection between airway cells and the brain.
Adult mice and other rodents sprout new nerve cells in memory - related parts of their brains.
A month after H7N7 or H3N2 infection, mice had fewer nerve cell connectors called dendritic spines on cells in the hippocampus, a brain region involved in memory.
Scientists made select nerve cells in mice's brains sensitive to light, and then used lasers to activate specific groups of those cells.
Researchers also studied the brain tissue of the infected mice under a microscope and found that the memory problems tracked with changes in nerve cells.
Two kinds of mouse glial brain cells, microglia and astrocytes, making different versions of the APOE protein were grown with brain nerve cells, or neurons, that make disease - causing forms of tau.
A microscope image shows nerve cells that relay information from the ear to the brain in mice.
They also tested other chemicals known to prevent the other two forms of cellular suicide, but only CGP3466B protected mouse nerve cells in the brain from death by cocaine.
In the current study, researchers found to their surprise that most of the nerve cells in auditory cortex neurons that stimulate brain activity (excitatory) had signaled less (had «weaker» activity) when the mice expected and got a reward.
To find out, the research team examined nerve cells from mouse brains for clues.
BRANCHING OUT In 1966, researchers thought that the branching ends of nerve cells (mouse neurons shown) might store memories in the human brain.
NERVE PROTECTORS The glowing cells in this micrograph of a mouse's optic nerve help shield electrical signals passing between eyes and bNERVE PROTECTORS The glowing cells in this micrograph of a mouse's optic nerve help shield electrical signals passing between eyes and bnerve help shield electrical signals passing between eyes and brain.
But active nerve cells in newborn mouse brains can't yet make this request, and their silence leaves them hungry, scientists report June 22 in the Journal of Neuroscience.
MISS MATCH After paw stimulation, nerve cells in the brain of a 7 - day - old mice become active (top row, left), but blood doesn't show up (bottom row, left).
In both mouse and fruit fly embryos, Detlev Arendt, an evolutionary biologist at the European Molecular Biology Laboratory in Heidelberg, Germany, has found that cells involved in forming the brain and nerve cord divide into three columns of cells.
Without the gene, the mice didn't have Neuroligin - 3 in their brains, a protein that helps nerve cells communicate.
The young mice showed signs of brain deterioration as well, including inflammation and decreased birthrates of new nerve cells.
Reported in Neuron, the new method enables researchers to peer deep inside a mouse's brain and watch astrocytes» influence over nerve - cell communication in real time.
The authors also found abnormalities in the subthalamic nucleus occur earlier than in other brain regions, and that subthalamic nucleus nerve cells progressively degenerate as the mice age, mirroring the human pathology of Huntington's disease.
Previously, Dr. Smeyne and his collaborator Dr. Stacey Schultz - Cherry in the Department of Infectious Disease at St. Jude Children's Research Hospital in Memphis, TN, showed that a deadly H5N1 strain of influenza (so - called Bird Flu) that has a high mortality rate (60 percent of those infected died from the disease) was able to infect nerve cells, travel to the brain, and cause inflammation that, the researchers showed, would later result in Parkinson's - like symptoms in mice.
The drug restored in the mice normal levels of serotonin, a neurotransmitter communicating messages between nerve cells in the brain.
One of Freeman's big projects is working with collaborators to study how nerve cells in the brains of mice respond to touch.
To see what was happening in the brains of these ankyrin - G mutant mice, the researchers analyzed the cell components in inhibitory synapses connecting with pyramidal neurons, finding that two proteins known as GAT1 and GAD67 — responsible for making the neurochemical GABA that dials back nerve impulses — were at much lower levels in the synapses on pyramidal neurons in ankyrin - G mutant mice than in normal mice.
Likewise, certain brain regions of these optogenetically stimulated, post-stroke mice showed increased levels of proteins associated with heightened ability of nerve cells to alter their structural features in response to experience — for example, practice and learning.
When investigators at the Stanford University School of Medicine applied light - driven stimulation to nerve cells in the brains of mice that had suffered strokes several days earlier, the mice showed significantly greater recovery in motor ability than mice that had experienced strokes but whose brains weren't stimulated.
VIDEO: 3D images of different Sst interneurons, or type of nerve cell, in the outer shell, or cerebral cortex, of the mouse brain.
Different Sst interneurons, or type of nerve cell, in the outer shell, or cerebral cortex, of the mouse brain.
Mice exposed to low - dosage of cannabis have more links between nerve cells in the brain, compared to those who were not exposed.
Scientists used mice to study how nerve cells in thalamic reticular nucleus work during sleep and how they help the brain concentrate.
When the scientists looked in the brain of a mouse with this mutation, they found, again, that MC4R was not on the nerve cell cilia where it should go to work.
Likewise, mouse microglia bioengineered to lack EP2 vastly outperformed unaltered microglia, in A-beta-challenged brains, at such critical tasks as secreting recruiting chemicals and factors beneficial to nerve cells and in producing inflammation - countering, rather than inflammation - spurring, proteins.
The researchers» findings suggest that Nav1.1 levels in special regulatory nerve cells called parvalbumin cells, or PV cells, are essential to generate healthy brain - wave activity — and that problems in this process contribute to cognitive decline in AD - mice and possibly in patients with Alzheimer's.
A microscope image shows the location in the brain of a mouse where nerve cells from the ear enter the brain and form cup - like synaptic connections with brain cells.
The researchers also discovered that the integrity of synapses was preserved much better in the olive oil group and the brain tissue of the mice that fed olive oil had increased autophagy activation of the nerve cells.
December 14, 2015 Brain cell death is a possible trigger of multiple sclerosis Multiple sclerosis (MS) may be triggered by the death of brain cells that make myelin, the insulation around nerve fibers, according to research on a novel mouse model developed by scientists from the University of Chicago and Northwestern MediBrain cell death is a possible trigger of multiple sclerosis Multiple sclerosis (MS) may be triggered by the death of brain cells that make myelin, the insulation around nerve fibers, according to research on a novel mouse model developed by scientists from the University of Chicago and Northwestern Medibrain cells that make myelin, the insulation around nerve fibers, according to research on a novel mouse model developed by scientists from the University of Chicago and Northwestern Medicine.
Nerve cells in the mouse brain that have been labeled with a modified rabies virus and fluorescent proteins.
In the 1960s, it was discovered that large amounts of MSG fed to infant mice destroyed nerve cells in the brain.
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