Sentences with phrase «mouse study compares»

«GM soybean oil causes less obesity and insulin resistance but is harmful to liver function: Mouse study compares Plenish to conventional soybean, coconut, and olive oils.»

Meanwhile a mouse study compared whey protein to isolated cysteine.

Not exact matches

In a new study based on mice, scientists at Lancaster University found that a drug that goes after three diabetes - related targets «significantly reversed the memory deficit» in mice who got the drug, as measured by their performance in a maze test when compared to mice who didn't get the drug.

A study published in January found that the immune response to the common cold in a test group of mice was impaired at the lower body temperature compared to the core body temperature.

However, in some studies with laboratory mice, Feinberg had observed that these epigenetic tags varied considerably among the mice even when comparing the same type of tissue in animals that have been living in the exact same conditions.

Previous studies on mice showed that Nanotax had a ten-fold higher maximum tolerated dose compared to paclitaxel.

To study the metabolic effects of beige fat, the researchers compared mice with Cx43 that are able to make beige fat normally to mice unable to make Cx43, meaning their white fat seldom got the message to change to beige in response to cold.

The study also found that SNCA mice displayed fragmented nighttime activity patterns compared to wild type controls and appeared to have a reduced overall sleep time.

The study compared intestinal wound healing in two groups of mice: 1) typical mice (wild type) found in nature and 2) mice genetically deficient in the healing factor IL - 10, specifically in macrophages, which impairs their ability to have normal wound repair.

In their study, the researchers showed that already at the age of six weeks in the mice with a rapid weight gain, the DPP4 gene was less methylated at four specific loci, i.e. epigenetically altered, compared to the other mice.

Intriguingly, in the new study, the brains of mice modeling autism that were fed the high - glycemic index diet had drastically less doublecortin, a protein indicator of newly developing neurons, compared to predisposed mice on the low - glycemic index diet.

He cites one published study in which researchers compared the efficiency of an injected antibiotic with an orally administered agent, and with their combination, in treating tuberculosis - infected mice.

Studies comparing the mouse and human sequences that accompany the mouse genome in the journal Nature suggest it provides plenty of new leads in biology and disease.

In the current study, the researchers of Kanazawa University in collaboration with the researchers of Kagome Co., Ltd. compared the mice fed with high - fat food supplemented with sulforaphane and the others with high - fat food but without sulforaphane in terms of their body weight.

Interestingly, when compared to human cellular models, mouse models of PD did not demonstrate the same toxic cascade, according to the study.

It highlighted differences in the structure and make up of human NMJs compared with those of mice and rats, which are routinely used in studying neuromuscular diseases.

Her study compared the myelination of these mice with that of mice in which FASN did occur.

During the study, Moeser compared the histamine responses of mice to two types of stress conditions — psychological and allergic — where the immune system becomes overworked.

This rejuvenated the stem cells in the bone marrow of the older mice that replenish their blood, and led to a wave of studies comparing the blood of old and young mice to try and identify the youth - giving substance.

Andrechek's federally funded study looked at mice containing all subtypes and compared the makeup of the rodent tumors and the way the genes acted, known as gene expression, to human tumor data.

«What we did in this paper is engineer our sensor to be about 15 times better than a previous version, and then compared it against a blood biomarker in a mouse model of ovarian cancer to show that we could beat it,» says Sangeeta Bhatia, the John and Dorothy Wilson Professor of Health Sciences and Technology and Electrical Engineering and Computer Science, a member of MIT's Koch Institute for Integrative Cancer Research and Institute for Medical Engineering and Science, and the senior author of the study.

The UTMB study found that when pregnant mice only drink water sweetened with fructose, a common sweetener in foods and beverages, their offspring have several more risk factors for heart disease, compared with mice who only drank water throughout pregnancy.

In a study in Proceedings of the National Academy of Sciences, Dr. Snyder and his colleagues compared gene expression in 15 different tissue types in mice and humans.

Professor Mark Viney and colleagues from the University of Bristol and the London School of Hygiene & Tropical Medicine studied the immune systems of 460 wild mice taken from 12 sites in the UK and compared them with mice bred in captivity.

Verma is quick to point out that although there have been two case studies in which BRCA1 mutations were linked to brain abnormalities, the dramatic effects documented in the mice in the study are unlikely to occur in women with a BRCA1 mutation, who still have some functioning BRCA1, compared with the mice who had none at all.

«Mouse and human kidney development compared: Findings may lead to advances in the study and treatment of kidney disease.»

«When we compared the gene signature activity of glioblastoma cells from around 60 patients we found that a large number of patients could be divided into subgroups that showed a correlation between gene activity, tumor cell characteristics and cell of origin similar to the one we had seen in the mouse study.

Bernard and her co-author Debrup Chakraborty, a postdoctoral student in her lab, studied mice that were fed a high - fat diet and discovered that this higher - risk layer of fat produced larger amounts of the fibroblast growth factor - 2, or FGF2, protein when compared to the subcutaneous fat.

In the new study, the researchers said the converted motor neurons compared favorably to normal mouse motor neurons, in terms of the genes that are turned on and off and how they function.

The study compared the effectiveness of the new tracer with 11C - choline (already widely used for imaging prostate cancer) in two mouse models and also performed the first PET / CT scan with 11C - sarcosine of a human with prostate cancer.

Male mice from 3 strains of genetically modified mice were used in these studies, with each strain compared with a specific background control strain: IL - 15Rα — KO (n = 20)(27) and B6129SF2 / J (B6129) control (n = 16); IL - 15 — KO (n = 8)(28) and BL / 6NTac control (n = 8); and HSA - IL - 15TG (n = 7)(34) and HSA - IL - 15Con control (n = 7).

In the study, the researchers found that GMSCs in mice with diabetes were less able to secrete extracellular vesicles compared to GMSCs in healthy mice, and their GMSCs also had less IL - 1RA secretion.

Kohn, who tracks the genetic roots of mice to see how favorable evolutionary traits develop, and Nakhleh, who studies evolution by comparing genomic data, shared their findings this week in the Proceedings of the National Academy of Sciences.

The importance of stromal POSTN was also demonstrated in another study in which orthotopic inoculation of gastric cancer cells into Rag2 − / −; Postn − / − mice reduced tumor size, decreased invasiveness, and decreased growth compared to Rag2 − / −; Postn + / + mice (Kikuchi et al., 2014).

To see what role the body's own immune system played in fighting infection, compared with gut microbes, the team also studied two strains of mice that have impaired immune systems.

In a report of the study's findings, published in the Journal of the American Medical Association on March 6, researchers compared professional pest management treatments plus education with education alone and found no significant differences in asthma symptoms or mouse allergen exposure between the two groups.

The new study compares genome - scale data of 21 mice that originated in 15 different locations in Europe and Africa.

The study showed that mice lacking the SNRK gene had a significantly higher concentration of macrophages in white fat tissue compared with normal mice.

The study found that both recombinant Osteolectin - and PTH - treated mice had significantly increased bone volume compared to untreated mice.

To study the link between PKC beta and atherosclerosis, scientists compared two groups of mice that were bred without the ability to produce apoliprotein E, a lipoprotein that removes cholesterol and lipids from the blood stream, giving them an innate tendency to develop atherosclerosis.

Both the knockout and normal phenotype data will be made available through the KOMP2 data coordination center so that researchers who acquire and study the knockout mice can compare various phenotypes.

«We discovered that the human DNA sequence, which only had 16 changes in it compared to the chimp sequence, was being expressed differently in mice,» said study author Debra Silver, an assistant professor of molecular genetics and microbiology in the Duke University Medical School.

As expected, tissue studies of the δ - sarcoglycan knockout mice revealed a distinctively different pattern of muscle damage when compared to the damage the researchers found in knockout mice missing the α - sarcoglycan gene.

It seems unlikely that this is the first mouse study where the mice got injected twice weekly, so there should be other studies that we should be able to compare the controls against to at least have any confidence on that explanation.

For their new study, scientists compared ancient mouse teeth with those of modern rodents that hang out near people who are only semi-settled.

Because he holds a dual appointment with The Jackson Laboratory, which studies mice, he is also seeking insight into how to reverse - engineer the process of regeneration in humans by comparing the genetics of the axolotl, which can regenerate, with those of the mouse, which for the most part can not.

Bottom Line: Bacterial load was significantly higher in pancreatic tumor samples from patients with pancreatic ductal adenocarcinoma compared with pancreatic tissue from normal individuals, and in studies using mice, eliminating certain «bad» bacteria slowed the growth of pancreatic cancer, reversed immune suppression, and upregulated the immune checkpoint protein PD1.

In addition to the reduction in total numbers of activated microglia in AFF 1 - treated TG mice, it is of note that costaining studies indicated that those activated microglia that did emerge in treated mice were highly colocalized with recalcitrant (proteinase K - resistant) AS aggregate as compared to untreated PDGF - AS mice.

By comparing short - and long - term treatment with CTEP in HD mice, Ferguson's team was able to study this question very closely.

Mouse models are useful for studying Alzheimer's disease, but they have their limitations when comparing results in humans.