Sentences with phrase «mouse study indicates»

Mouse study indicates signaling molecules at play in cancer may also promote atherosclerosis

Not exact matches

While study results indicated that combining capsaicin with the chemicals «might promote cancer cell survival,» the report clearly stated that the control group of mice treated only with capsaicin ``... did not induce any skin tumors...» In addition, the study repeatedly cited other research studies in which the anti-cancer properties of capsaicin were solidly demonstrated.

Osterhout studied the mouse embryos as they developed, tracking them to see when GFP glowed green, indicating a retinal ganglion cell was born.

The new study indicates that such infections in the mice cause the number of tuft cells to increase by five - to tenfold, leading the norovirus to replicate more efficiently.

Further studies indicated that social experience with a female seemed to be the key requirement for the mice to develop separate, sex - specific populations of neurons, as well as aggressive behavior.

«Our results indicate that the epigenetic modification we studied makes both mice and humans more susceptible to obesity and with increasing age increases their risk of developing a fatty liver,» said Anne Kammel, first author of the study.

Studies in mice indicated that drugs that activate the surface protein TRPA1 on pain - sensing nerve cells intensify postoperative pain.

Earlier mouse studies by Li and his collaborators had indicated that the expression of several imprinted genes changes as hematopoietic stem cells embark on their journey from quiescent reserve cells to multi-lineage progenitor cells, which form the many highly specialized cell types that circulate within the blood stream.

Although we did observe positive effects on some aging traits, such as memory impairments and reduced red blood cell counts, our studies showed that similar drug effects are also seen in young mice, indicating that rapamycin did not influence these measures by slowing aging, but rather via other, aging - independent, mechanisms.»

Evolution has preserved the «neuropeptide Y (NPY) system», as it is known, in most species — indicating its importance — and much of our understanding comes from studying it in mice.

Remarkably, although mouse studies had indicated that different transcription factors were differently important for generating pain and itch sensing neurons versus pressure and limb position neurons, in the dish these factors produced equal numbers of each of the three main subtypes.

«Previous studies in mice have indicated that bacteria that are able to encroach upon the epithelium might be able to promote inflammation that drives metabolic diseases, and now we've shown that this is also a feature of metabolic disease in humans, specifically type 2 diabetics who are exhibiting microbiota encroachment.»

Previous research indicated this was the case in mice, but this is the first study to document presymptomatic dysfunction in humans.

Their study in aged mice indicates that high folic acid intake causes lowered immune function because natural killer (NK) cells, a particular type of immune cell, are less effective.

Combined with previously published studies, our data indicate that infection with all three major North American T. gondii clonal lineages results in loss of innate, hard - wired aversion to feline predator urine in mice.

In this regard, animal model studies with FIPV in cats and RSV in mice have indicated that viral surface proteins may be the sensitizing protein of inactivated vaccines for immunopathology with infection [32], [45].

In addition to the reduction in total numbers of activated microglia in AFF 1 - treated TG mice, it is of note that costaining studies indicated that those activated microglia that did emerge in treated mice were highly colocalized with recalcitrant (proteinase K - resistant) AS aggregate as compared to untreated PDGF - AS mice.

Our mechanistic studies, in both mouse and human mammary cancer cells, indicate that leptin and LepR are necessary for NANOG expression.

However, recent evidence indicates that apoE4 expression compromises the blood - brain barrier (as does apoE deficiency).40 Studies of brain histology, neurodegenerative markers, cholinergic activity, and neuronal function in knockout mice have been equivocal.39 Failure of detailed neurocognitive and retinal studies to demonstrate defects in our patient suggests either that the functions of apoE in the brain and eye are not critical or that they can be fulfilled by a surrogate pStudies of brain histology, neurodegenerative markers, cholinergic activity, and neuronal function in knockout mice have been equivocal.39 Failure of detailed neurocognitive and retinal studies to demonstrate defects in our patient suggests either that the functions of apoE in the brain and eye are not critical or that they can be fulfilled by a surrogate pstudies to demonstrate defects in our patient suggests either that the functions of apoE in the brain and eye are not critical or that they can be fulfilled by a surrogate protein.

«While past research indicated that only mice with compromised immune systems are susceptible to Zika virus infection, this study shows that neonatal mice with otherwise healthy immune systems are also susceptible,» according to the FDA news release.

For example, results of a mouse study conducted by the National Institutes of Health (NIH) in collaboration with ChromaDex published in November 2014 indicated that NR was effective at restoring NAD + levels in mitochondria and rescuing phenotypes associated with a devastating accelerated aging disease known as Cockayne Syndrome (CS).

The study results indicated unfavorable atherosclerotic changes when mice followed a low carb / high protein diet.