Genes associated with the following forms of inherited canine retinal diseases were tested for association using fragment analysis in 11 PRA - affected and 11 unaffected Swedish vallhund dogs: canine
multifocal retinopathy (cmr; gene: BEST1)[8], [9], rod - cone dysplasia type 1 (rcd1; PDE6B) and type 3 (rcd3; PDE6A)[23]--[26], progressive rod - cone degeneration (prcd; PRCD)[27], canine Leber congenital amaurosis (LCA; RPE65)[6], [7], cone - rod dystrophy (crdSWHD, NPHP4)[28], and achromatopsia / cone degeneration (ACHM / cd; CNGB3)[29], [30].
Dr. Hoffman recognized the similarity of these lesions to those known to occur in other breeds affected with Canine
Multifocal Retinopathy and he contacted OptiGen about the case.
Canine
Multifocal Retinopathy (CMR)-- blister - like defects in the retina which can be detected by 4 months of age.
Canine
multifocal retinopathy, cone degeneration, corneal dystrophy, eyelid defects, hyaloid artery remnants, micropapilla, PHPV / PTVL, and uveodermatologic syndrome are occasionally seen in the breed.
The most common eye diseases in the breed are cataracts, distichiaisis, persistent pupilary membrane, and iris coloboma, with Progressive Rod Cone Degeneration (PRCD), a form of progressive retinal atrophy (PRA), Collie Eye Anomaly (CEA), Canine
Multifocal Retinopathy (CMR), and glaucoma have been seen but are rare.
Other eye diseases include, roughly in order of frequency, cataract, distichiasis, progressive rod - cone degeneration (a form of PRA), CEA, iris coloboma, persistent pupilary membrane, cone degeneration, and canine
multifocal retinopathy.
Canine
Multifocal Retinopathy (CMR) is an autosomal recessive eye disorder known to affect Great Pyrenees, English Mastiffs, Bullmastiffs, Australian Shepherds, Dogue de Bordeaux, English Bulldogs, American Bulldogs, Coton de Tulears, Perro de Presa Canario, and Cane Corsos.
Animal Genetics offers DNA testing for Canine
Multifocal Retinopathy Types 1 and 2.
Not exact matches
Unrelated to the herein described phenotype specific to Swedish vallhund
retinopathy, we also observed focal and
multifocal inactive chorioretinal scars in a number of dogs (n = 14).