Sentences with phrase «mycobacterium tuberculosis infection»

«Our study has provided basic evidence that curcumin protects against Mycobacterium tuberculosis infection in human cells,» said Dr. Xiyuan Bai, lead author of the study.

Lindestam Arlehamn CS, Gerasimova A, Mele F, Henderson R, Swann J, Greenbaum JA, Kim Y, Sidney J, James EA, Taplitz R, McKinney DM, Kwok WW, Grey H, Sallusto F, Peters B, Sette A. Memory T cells in latent Mycobacterium tuberculosis infection are directed against three antigenic islands and largely contained in a CXCR3 + CCR6 + Th1 subset.

She is registred to the National Order of Biologists in the province of Palermo; collaboration in research project from 2012 to 2015 at the Department of Biopathology and Biotechnology, University of Palermo, focusing the study on the identification of molecules capable to modulate intracellular metabolic pathways for the prevention and treatment of infectious, tumor and degenerative disease, in collaboration with Prof. Angela Santoni, University of Rome; collaboration in research project in 2011 at the hospital «Villa Sofia Cervello» of Palermo to study methods can cure the genetic defect that causes thalassemia through genetic engineering; she studies different mechanisms of the differentiation and the activation of human gammadelta T cells as effector cells of the immune response against cancer and infectious diseases; she investigates about the identification and development of biomarkers of resistance and susceptibility to Mycobacterium tuberculosis infection; Valentina Orlando has published 13 papers in peer reviewed journals and 3 comunications at national and international congress.

Pharmacological Inhibition of Host Heme Oxygenase - 1 Suppresses Mycobacterium tuberculosis Infection In Vivo by a Mechanism Dependent on T Lymphocytes.

Not exact matches

However, because Mycobacterium tuberculosis has developed many ways to evade the normal immune response, infections become chronic because a stalemate develops between the pathogen and the host.

The bacterium that causes tuberculosis, Mycobacterium tuberculosis, or Mtb, previously was thought to infect the body only through inhalation and subsequent infection of cells in the lungs.

Researchers increasingly recognize that latent TB infection includes diverse responses to infection with Mycobacterium tuberculosis (the pathogen that causes TB) and thus variable outcomes.

Gilleron M *, Stenger S *, Mazorra Z, Wittke F, Mariotti S, Böhmer G, Mori L, Puzo G, DeLibero G. Diacylated sulfoglycolipids are novel mycobacterial antigens stimulating CD1 - restricted T cells during infection with Mycobacterium tuberculosis.

Caused by a bacterial infection with Mycobacterium tuberculosis (MTb), TB most commonly affects the lungs but can affect any organ in the body.

The primary causative agent in humans is Mycobacterium tuberculosis, whereas TB in wildlife results from infection by Mycobacterium bovis.

TB kills more people than any other infectious disease, and the causative bacterium, Mycobacterium tuberculosis, is becoming increasingly resistant to antibiotics used to treat the infection.

Specifically, the authors call for systems biology approaches (using large data sets and modeling to understand complex biological systems) to fill critical knowledge gaps in understanding how Mycobacterium tuberculosis (Mtb) infection causes disease.