Sentences with phrase «nf kappa»

In CLL and other B - cell malignancies researchers have previously observed that deregulation of the NF kappa B (NF - kB) signalling pathway appears to be particularly important.

Not exact matches

In animal studies, activation of nuclear factor - kappa B (NF - kB); activation of inducible nitric oxide synthase (iNOS), and cyclooxygenase - 2 (COX - 2); and formation of malondialdehyde (MDA) have all be shown to get reduced following consumption of either sweet potato or its color - containing extracts.

Most of the commonly occurring cancers, notably breast, prostate, and lung cancer, spread (metastasize) to bone; I was set to the task of studying the role of a transcription factor (gene - expression regulator), NF B (nuclear factor kappa B), in cancer metastasis.

For example, nuclear factor - kappa B (NF - kB) is a complex of proteins that acts as a master switch for turning inflammation genes on and for controlling cell death.

Working with cultures of respiratory tract cells, Elias's team found that the gene that codes for il - 6 is inactive unless a protein known as nf - kb (nuclear factor - kappa beta) attaches to the gene.

Not only did the CLA's impact on NF - kappa - B activity reduce the production of the COX - 2 enzyme, but it also dampened the activity of any COX - 2 that was made.

They found that it modulated the activity of a molecule, NF - kappa - B, that controls parts of the immune response.

As a monomer, GR represses the activities of pro-inflammatory transcription factors, such as activator protein 1 or nuclear factor kappa B (NF - kB) by a tethering mechanism called transrepression.

The paracaspase MALT1 cleaves HOIL1 reducing linear ubiquitination by LUBAC to dampen lymphocyte NF -[kappa] B signalling.

HYPERTONIC SALINE ATTENUATES TNF -[alpha]- INDUCED NF -[kappa] B ACTIVATION IN PULMONARY EPITHELIAL CELLS.

Inhibits the activity of dimeric NF - kappa - B / REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals.

Postshock Mesenteric Lymph Induces Endothelial NF -[kappa] B Activation.

Control of the senescence - associated secretory phenotype by NF --LCB- kappa -RCB- B promotes senescence and enhances chemosensitivity.

Li, Y.; Reddy, M. A.; Miao, F.; Shanmugam, N.; Yee, J. - K.; Hawkins, D.; Ren, B.; Natarajan, R. Role of the Histone H3 Lysine 4 Methyltransferase, SET7 / 9, in the Regulation of NF --LCB- kappa -RCB- B - dependent Inflammatory Genes: RELEVANCE TO DIABETES AND INFLAMMATION.

Proinflammatory cytokines enhance estrogen - dependent expression of the multidrug transporter gene ABCG2 through estrogen receptor and NF -LCB- kappa -RCB- B cooperativity at adjacent response elements.

Its binding to DPP4 induces T - cell proliferation and NF - kappa - B activation in a T - cell receptor / CD3 - dependent manner.

Interferons Inhibit Tumor Necrosis Factor --LCB- alpha -RCB-- mediated Matrix Metalloproteinase - 9 Activation via Interferon Regulatory Factor - 1 Binding Competition with NF --LCB- kappa -RCB- B

Analysis of Genes Induced by Sendai Virus Infection of Mutant Cell Lines Reveals Essential Roles of Interferon Regulatory Factor 3, NF --LCB- kappa -RCB- B, and Interferon but Not Toll - Like Receptor 3

One particularly bad guy in high amounts is the inflammatory nuclear factor kappa B, or NF - kB for short.

It works by activating the inflammatory nuclear factor kappa B (NF - kB for short), which binds to your DNA and triggers a number of inflammatory cascades throughout the body.

Researchers have found that they help turn off NF - kappa B, a protein that regulates the immune system and triggers the process of inflammation.

Zinc assists in regulating an immune system protein called NF - kB (Nuclear FActor - kappa Beta) by reducing inflammation and serving as an antioxidant to prevent oxidative stress.

In addition to the metabolic activities described above, food flavonoids have also been shown to suppress inflammatory signaling in another metabolic pathway called the nuclear factor kappa - B (NF - kB) pathway.

According to the Journal of Biological Chemistry, «Curcumin has been shown to block many reactions in which NF - kappa B plays a major role.

Oxidative stress in tissue cells may trigger an inflammatory response by the NF - kappa B nuclear signaling pathway.

(23) It is believed that curcumin may inhibit the molecules known to play major roles in inflammation, including NF - kappa B, by inhibiting their activation.

It has also been shown to help control the expression of certain proteins that are related to a cancerous process, such as modulating the expression of proteins 5 - LOX, TNF (tumor necrosis factor), NF - kappa B, COX - 2 and others.

Tags for this Online Resume: biomarkers, immunologist, skin, clinical pharmacology, NF - kappa B, signaling

Daily meditation in distressed dementia decreases NF - kappa B signaling and increases interferon response factor transcription