Sentences with phrase «nf1 is a tumor»

For some companies meetings are a tumor of unproductiveness waiting to be excised, while for others they're the lifeblood of the company's communication in chaotic times.

So tomtom, how about a plate that says «I was a tumor until I was born?»

So's a tumor.

They only deal in the abstract like the imagination unlike real Doctors of practical medicine that can say this is cancer, this is the flu, this is a tumor and this is a broken bone.

They are tumor factories.

With his kind of cancer, there were no tumors to X-ray, no reliable way to chart the course of the disease.

«It's a tumor,» they said.

BRCA1 is a tumor - suppressor gene; the deletion of the two letters disabled its protective function.

«Are tumor cells glutamine addicts?.»

The study, «The nuclear transport receptor Importin - 11 is a tumor suppressor that maintains PTEN protein,» which will be published online February 13 in The Journal of Cell Biology, suggests that the loss of Importin - 11 may destabilize PTEN, leading to the development of lung, prostate, and other cancers.

They found that miR - 21 is degraded in a process that involves PAPD5, an enzyme known to be a tumor suppressor.

Tumors with high numbers of TMEM sites (i.e., they have a high TMEM «score») were more likely to metastasize than were tumors with lower TMEM scores.

I'm interested in doing a film on proton therapy, for example, because I have a tumor in my brain; it's the tumor that affected my eyesight as a child.

One protein that keeps healthy cells from behaving this way is a tumor suppressor named p53.

«This is the best example that NF1 is a tumor suppressor,» says David Viskochil, a geneticist at the University of Utah, although he cautions that the case is not yet closed: There still could be other genes that play a role in NF tumor development.

Scientists already had reams of circumstantial evidence that NF1 was a tumor suppressor.

Among them: some genes believed to be tumor suppressors turned on or became more active, whereas certain disease - promoting ones, including oncogenes (in the so - called RAS family that are implicated in both prostate and breast cancer), were down - regulated or switched off.

«Also, because Notch is known to be a tumor suppressor, the essential role of Rumi in Notch activation suggests that Rumi could be a tumor - suppressor as well.

You might guess that these are tumors.

«Is this a tumor suppressor gene?

P53 is a tumor suppressor gene, a protein that regulates cell growth, and it is the most frequently mutated suppressor gene in cancer.

The expected outcome, if MYC was the sole driver of the cancer, was tumor growth on the MYC line as well as the paired line.

«It indicated that, under this specific circumstance, p300 is a tumor suppressor, offering great insight into how MDS converts to leukemia.

«Foxo1 is a tumor suppressor gene, but it promotes B cell proliferation in the germinal center,» he said.

For example, the robot - mass spec combo might be useful to dermatologists who often probe lesions on the skin, which have distinct molecular signatures depending on if the lesion is a tumor or normal skin tissue.

«Even though Foxo1 is a tumor suppressor gene, paradoxically its activity is associated with lymphomas,» said Kurosaki.

Under the microscope, it is possible to identify invasion of the tumor into the lymph and blood vessels, this being the tumor behaviour responsible for the formation of metastases, so that it can be used as a prognostic factor.

Pten (short for phosphatase and tensin homolog) is a tumor suppressor that is defective in about 20 - 25 percent of all patients with cancers.

A meningioma is a tumor, usually benign, that arises from the meninges — the membranes that surround the brain and spinal cord.

The main established prognostic factors are tumor size and differentiation grade, spreading to armpit lymph nodes, hormone receptor status and HER2 - positivity.

«There are some tumors that will not be that relevant,» Fan said.

In breast cancer, miR - 21, 155, 27, 96, 182, and 128 were identified as oncogenes, whereas miR - 125, 205, 27, 17, 206, and 145 were found to be tumor suppressor genes, and their corresponding target genes were also defined (10 — 12).

Context, tissue plasticity, and cancer: are tumor stem cells also regulated by the microenvironment?

Being both tumor - specific and widely expressed in human tumors, MAGE - A3 is an ideal cancer vaccine target and will be the focus of many clinical trials, including the largest clinical trial ever conducted in lung cancer, MAGRIT, launched by GlaxoSmithKline in 2007.

Melanoma is a tumor that is recognized by the immunological system and mechanisms leading to an anti-tumor immune response of potential value in the adjuvant setting.

Regarding p21 - null mice, it was originally reported (9) that they are tumor - free at least until 7 months of age.

The term «tumor stem cell» only reflects the fact that this is a tumor cell with capacities similar to normal stem cells, such as the capability to maintain itself indefinitely.

In nonneuronal tissue, SEMA3B has been postulated to be a tumor suppressor gene of lung and breast cancer.

Several factors have been reported to induce the expression of p21waf1 / cip1 and the most important one is the tumor suppressor p53 (16).

[13] Another mechanism of immune evasion is tumor expression of programmed death ligand 1 (PD - L1)(also known as B7 - H1 or CD274) on many cancer types including RCC.

Some of the most well - known biomarkers are tumor specific: PD - L1 for kidney, lung, bladder cancer and melanoma; BRCA for breast cancer; BRAF for melanoma; and HER - 2 for breast cancer.

We spoke with Dr. Ribas about what it's like to be a tumor immunologist at this exciting time.

It is widely believed that cellular senescence is a tumor suppressor mechanism; however, it has not been understood why it is advantageous for organisms to retain mutant cells is a postmitotic state rather than simply eliminating them by apoptosis.

For example, cellular senescence is tumor suppressive and overcoming the senescence - associated cell growth arrest is a necessary step during cell transformation.

One barrier to successful cancer immunotherapy is the tumor microenvironment, which recruits immunosuppressive cells that can inhibit endogenous anti-tumor responses.

«We expected Ezh2 to be an oncogene in this aggressive tumor, but our gene - editing work revealed it to be a tumor suppressor,» said corresponding author Martine Roussel, Ph.D., a member of the Department of Tumor Cell Biology at St. Jude Children's Research Hospital.

The resulting DNA copy number variation and patterns of chromosome loss and gain are tumor - type specific, suggesting differential selective pressures on the two tumor cell types.

The tumor need double only about 30 times, and we're up to a billion cancer cells — which is a tumor just large enough to be picked up by mammography.

The problem, of course, is that some of the new additions may be tumors.

You keep me hopeful though that I may be tumor free, seizure free and medication free one day as well.