Sentences with phrase «nkg2d immunoreceptor»

Here, we show that in the antibody - mediated autoimmune disease pemphigus vulgaris (PV), autoantigen - based chimeric immunoreceptors can direct T cells to kill autoreactive B lymphocytes through the specificity of the B cell receptor (BCR).

The sequence, called an ITAM (immunoreceptor tyrosine - based activation motif), encodes a piece of protein that can by itself signal immune system cells to multiply and go to work.

Larry Samelson provides the first demonstration that the TCR is coupled to tyrosine kinase pathways, now known to be true for all immunoreceptors.

Structurally distinct phosphatases CD45 and CD148 both regulate B cell and macrophage immunoreceptor signaling.

The BCR - ABL inhibitor ponatinib inhibits platelet immunoreceptor tyrosine - based activation motif (ITAM) signaling, platelet activation and aggregate formation under shear.

NKG2D is a type of immunoreceptor — a molecule present on the surface of the body's immune cells that recognises signals from normal cells that are distressed.

Now, a research team at Imperial College London has found that in a mouse model developing liver cancer, one immunoreceptor — attractive candidate for immunotherapies — promoted rather than delayed tumour growth.