Nanobodies binding GFP were designed in 2009.
Not exact matches
Hansman's research team recently discovered that a «
nanobody» called Nano - 85 was able to
bind to intact norovirus - like particles (VLPs) in culture.
About 20 years ago, it was discovered that the unique immune systems of camelids (llamas, camels, and alpacas) produce a pared down version of antibodies, featuring a single
binding domain called a
nanobody.
Nanobodies will
bind to the column due to their N - terminal His14 - bdNEDD8 tag.
Subsequent work showed that
nanobodies could be fused to other proteins, and these fusions retained the ability to
bind GFP.
Once Tang and Cepko found a description of GFP -
binding nanobodies, the project really took off.