They tested 120
neural stem cell lines in the lab for stability and robustness and in animals for the capacity to engraft with minimal immune rejection.
Neural stem cell lines derived from human fetal brain tissue achieved the same feats, the researchers report in the October issue of Nature Neuroscience.
Two weeks later, the researchers found the brain - derived cells in the regenerating muscle tissue — suggesting that
neural stem cell lines might be candidates for treating certain muscle diseases.
Not exact matches
Furthermore, they have found that
neural stems cells can be culled from the patient's bone marrow, thus circumventing ethical and political obstacles to
neural stem cell therapy as well as problems with immune rejection that sometimes arise when researchers must employ embryonic
stem cell lines.
Researchers from the University of Cambridge studied a variety of
cell lines, including human
neural stem cells, to investigate how Zika virus infection can lead to microcephaly.
However, we have found a fluorescent marker for nestin, a
neural crest
stem cell marker, in the posterior limbal region of the human anterior segment in the vicinity of both the trabecular meshwork and Schwalbe's
line (unpublished).
NeuroStemcell is focused on the identification and systematic comparison of progenitor
cell lines with the most favourable characteristics for mesDA and striatal GABAergic neuronal differentiation, generated either directly from human embryonic
stem (ES) cells, from Neural Stem (NS) cells derived from ES cells or fetal brain, from induced Pluripotent Stem (iPS) cells or from in vitro short - term expanded neural progenitors from ventral midbrain grown as neurospheres (VMN, Ventral Midbrain Neurospheres) 4, and perform rigorous and systematic testing of the most prominent candidate cells in appropriate animals mod
stem (ES)
cells, from
Neural Stem (NS) cells derived from ES cells or fetal brain, from induced Pluripotent Stem (iPS) cells or from in vitro short - term expanded neural progenitors from ventral midbrain grown as neurospheres (VMN, Ventral Midbrain Neurospheres) 4, and perform rigorous and systematic testing of the most prominent candidate cells in appropriate animals m
Neural Stem (NS) cells derived from ES cells or fetal brain, from induced Pluripotent Stem (iPS) cells or from in vitro short - term expanded neural progenitors from ventral midbrain grown as neurospheres (VMN, Ventral Midbrain Neurospheres) 4, and perform rigorous and systematic testing of the most prominent candidate cells in appropriate animals mod
Stem (NS)
cells derived from ES
cells or fetal brain, from induced Pluripotent
Stem (iPS) cells or from in vitro short - term expanded neural progenitors from ventral midbrain grown as neurospheres (VMN, Ventral Midbrain Neurospheres) 4, and perform rigorous and systematic testing of the most prominent candidate cells in appropriate animals mod
Stem (iPS)
cells or from in vitro short - term expanded
neural progenitors from ventral midbrain grown as neurospheres (VMN, Ventral Midbrain Neurospheres) 4, and perform rigorous and systematic testing of the most prominent candidate cells in appropriate animals m
neural progenitors from ventral midbrain grown as neurospheres (VMN, Ventral Midbrain Neurospheres) 4, and perform rigorous and systematic testing of the most prominent candidate
cells in appropriate animals models.
Further phenotypic characterization revealed that LKB1 is required for the differentiation and maintenance of two NCC - derivatives, Schwann
cells and the ENS. Using a model of
neural crest
stem cell line, we demonstrated that Lkb1 is key for
neural crest - derived glial commitment.
The self - renewable capacity of these
cells, their ability to differentiate into several tissue progenitors (
neural, mesenchymal
stem cells...), and the possibility to work with mutated
cell lines define human
stem cells as a good basis for screening compounds libraries in order to discover new potential drugs for monogenic diseases.
Stice's
neural cell kits created from human embryonic
stem cell lines last up to six months.