Neuronal cells express a pp60c - src variant that displays an altered electrophoretic mobility and a different V8 peptide pattern relative to pp60c - src expressed in tissues of non-neuronal origin.
Not exact matches
The neurons
express a pan
neuronal marker Map2 in green and a percentage of the
cells express a marker for inhibitory neurons, GABA, in red.
They play a pivotal role in regulating synaptic transmission, modulating excitotoxicity responsible for much of the
neuronal damage caused by hypoxic insult in the brain [37], and are
expressed in retinal photoreceptors, horizontal
cells, and bipolar
cells as well as the amacrine and ganglion
cells of the inner retina [38 — 41].
They are broadly
expressed in excitable and non-excitable
cells, and have in turn been implicated in a large spectrum of physiopathological processes, ranging from the regulation of
neuronal excitability, respiratory and cardiac function to the control of
cell volume, hormone secretion and
cell proliferation.
The technique, which was used in this work to track how mRNA
expresses itself in
neuronal stem
cells as they differentiate, could help us better understand neurogenesis and perhaps even be used to screen drugs for treating neurodegenerative diseases and brain trauma.
Glial
cell line - derived neurotrophic factor (GDNF) was selected based on clear evidence that it increases
neuronal sprouting, prevents
cell death [20], [21] and has neuroprotective effects in the brain [11], [22]--[24], spinal cord [12] and retina [25]--[30], and because receptors for GDNF are
expressed within mature retina [26], [31]--[34].
Upon engraftment into the medial prefrontal cortex in rats, the homolog of the human anterior cingulate cortex, the
cells assumed
neuronal morphologies,
expressed monoaminergic - specific proteins, and seemed to functionally integrate, as assessed by the upregulation of the immediate - early gene, cfos.
TNFR1 is
expressed on most
cell types, while TNFR2 expression is restricted to endothelial, hematopoietic and some
neuronal populations [37], [38].
After 4 weeks of differentiation, the majority of the
cells (> 60 %)
expressed the postmitotic
neuronal marker β - III tubulin with a subset (about 50 % of total neurons) additionally
expressing TH, a marker for midbrain dopaminergic neurons (Fig. 3A — D).
I need help on how to generate a stable
neuronal cell line
expressing prion protein via pre-transfection restriction enzyme digestion of plasmid DNA using lipid reagent.