Sentences with phrase «new cellular response»
«New cellular response to radiation exposure: Must we reconsider the risks of low doses?.»
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As a basic researcher, he has been most interested in looking for ideas that point toward new directions in the field: a new role for a protein or a new understanding of how cellular proteins drive the immune response.
Professor Fallon said: «This identification of an early stage cellular checkpoint that can act as a break on allergic responses has important implications for the development of new therapeutic approaches for asthma and other allergic diseases.»
«Our experiments suggest that mGluR5 amplifies the cellular response to a chemical signal, and that by blocking mGlur5 receptors in inhibitory neurons involved in depression, these new therapies can achieve an antidepressant effect,» says senior author Paul Greengard, Vincent Astor Professor and head of the Laboratory of Molecular and Cellular Neuroscience.
Although other tRNA halves have been described before — specifically those that are produced during a cellular stress response — this discovery represents a new and distinct species of tRNA halves that the authors coined SHOT - RNAs, for sex hormone dependent tRNA - derived RNAs.
We are particularly interested in leverage our interdisciplinary expertise in polymer chemistry, nanomedicine, drug delivery and immunobiology to innovate new approaches to modulate the tumor microenvironment and enhance cellular immune responses to cancer vaccines.
The lab focuses on clarifying the mechanisms of brain plasticity, gene expression, and responses of cellular elements to different psychotropic drugs, and have identified several novel brain sites and pathways that constitute attractive targets for new drug development.
Altieri and his team are currently focused on three programs to understand the biology of survivin with respect to cell cycle progression, in particular, mitosis, cell survival and the cellular stress response and how exploiting these pathways may provide new cancer therapeutics.
Systems biology aims to study complex cellular systems by systematically stimulating them, monitoring cellular responses, formulating mathematical and computational models to understand the data, and proposing new experiments to refine these models.
«For example, you could figure out patterns of toxicity of potential new drug compounds by looking at cellular responses and finding common responses to other known toxic molecules.»
Characterizing the molecular pathways regulating genomic stability at damaged replication forks in HR - deficient cancers will increase our understanding of the cellular response to replicative stress, and in the same time, potentially allow the identification of new predictors (biomarkers) of chemo - sensitivity / resistance in these tumors (Figure 2B).
«At the cellular level, trauma and exercise resemble each other, with inflammation being the common response,» says Dr. Catherine Dudick, trauma surgeon at AtlantiCare Regional Medical Center in Atlantic City, New Jersey.