Sentences with phrase «new immunosuppressive»
Not exact matches
The goal of the new approach is to convert that immunosuppressive environment into an «immunostimulatory» one, Goldberg says — a condition in which the immune system is primed for an offensive against cancer cells.
https://www.sciencedaily.com/
«This treatment is a new form of cell transplantation that utilizes the patient's own cells, so it does not require immunosuppressive drugs and, thus, avoids the side effects of those drugs,» says Scott Nyberg, M.D., Ph.D., a liver transplant surgeon at Mayo Clinic.
Ultimately, the team hopes to inject BMP - 7 directly into the pancreas to stimulate the creation of new beta cells, allied with a small amount of immunosuppressive drugs to stop the new insulin factories being destroyed by the immune system.
The JDF Center for Islet Cell Transplantation will fund 32 researchers to focus on four main goals: Reversing the overactive immune response that kills islet cells; finding new sources for islet cell transplants, such as pigs or genetically engineered cells; persuading the body to accept the transplanted cells without immunosuppressive drugs that often trigger worse side effects than the disease; and overcoming the technical difficulties of transplantation.
By receiving transplants of bone marrow cells along with the new kidney, four of five transplant patients with end - stage renal disease were able to stop taking immunosuppressive drugs within about one year after surgery.
Genetically modified «hunter» T cells successfully migrated to and penetrated a deadly type of brain tumor known as glioblastoma (GBM) in a clinical trial of the new therapy, but the cells triggered an immunosuppressive tumor microenvironment and faced a complex mutational landscape that will need to be overcome to better treat this aggressive cancer, Penn Medicine researchers report in a new study this week in Science Translational Medicine.
«New tool to study an important anti-cancer, immunosuppressive target.»
Ming Li, Ph.D., a CLIP grantee at Memorial Sloan Kettering Cancer Center in New York, New York, is studying an immunosuppressive pathway that is activated in tumor - associated immune cells in breast cancer models.