Sentences with phrase «nonendosomal cellular uptake»

The team demonstrated that cell sex considerably influenced cellular uptake of nanoparticles and found that cells from men and women responded differently to reprogramming techniques used to enhance the ability of the cells to differentiate into a greater variety of cell types.

«While nanoparticle shape has been shown to impact cellular uptake, the latest study shows that specific tissues can be targeted by controlling the shape of nanoparticles.

For instance, three scavenger receptor genes were suggested to facilitate the cellular uptake of carotenoids in the adductor muscles of orange - adductor Yesso scallop [13].

Apart from the various biomedical applications of nanomaterials, especially in cancer therapy, cellular uptake of nanoparticles is a key factor in recent years for efficient drug delivery applications.

The bioconjugate and unmodified QD treatments (the control) were tested for cellular uptake and cytotoxicity in MCF7 (cancerous) and MCF - 10A (comparison) cell cultures.

Functionalisation of silver nanoparticles with monosaccharides modulates their cellular uptake and toxicity.

Observed toxicity was strongly correlated with intracellular oxidative stress, measured as protein carbonylation, but not to cellular uptake.

9:45 — 10:15 Filippo Mancia (Columbia Uni) The molecular mechanisms underlying cellular uptake of vitamin A

(ii) the carbohydrates on the surface can serve as targeting molecules and trigger cellular uptake via specific receptors or mediate specific cellular responses [10].

Here, we discuss the toxicity and the cellular uptake of different silver nanoparticles functionalized with citrate, three different monosaccharides as well as ethylene glycol on two different cell lines.

Carbohydrate coating on silver nanoparticles modulates both oxidative stress and cellular uptake, but mainly the first has an impact on toxicity.

Quantitative evaluation of cellular uptake and trafficking of plain and polyethylene glycol - coated gold nanoparticles.

Nevertheless, little is still known about the influence of carbohydrates on the toxicity and cellular uptake of nanoparticles.

It was found that toxicity correlates with oxidative stress rather than with cellular uptake.

Toxicity correlated to oxidative stress but not to cellular uptake.

Insulin functions include: Lowering blood glucose Promoting cellular uptake of carbohydrates, amino acids and fatty acids Promoting fat storage (when at excessive levels) Insulin is a powerful anabolic hormone because it moves amino acids into muscle cells.

Glutamine both stimulates mTOR directly through the ARF1 pathway and indirectly by regulating cellular uptake of leucine to stimulate mTOR through the RAG pathway.

Insulin assists with cellular uptake of glucose from the bloodstream into the cells of the body for energy.

Insulin promotes the efficient storage and use of glucose molecules by controlling their transport across cell membranes, permitting cellular uptake and metabolism of glucose.

Throughout my career I have demonstrated successful Successfully designed and implemented bioassay and cell culture automation strategies, novel cellular uptake and substrate depletion assay methodologies in the pharmaceutical industry.

Successfully designed and implemented bioassay and cell culture automation strategies, novel cellular uptake and substrate depletion assay methodologies.

Not exact matches

Peptides can bind to targets on a cell (usually receptors or enzymes that are themselves proteins) and so regulate cellular functions such as nutrient uptake or communication between cells.

The team also showed that the cellular process macropinocytosis, which participates in cell scavenging nutrients and vesicles, contributes to exosomes uptake in cancer cells with mutant KRAS.

«By offering the distinct advantage of subcellular resolution and avoiding the undesirable influence of fluorescent dyes, we believe our technique can complement FDG in clinical PET imaging for visualizing glucose uptake activity at the cellular level,» says the lead author Fanghao Hu, a Ph.D. candidate in chemistry.

To image glucose uptake activity at the cellular level, glucose analogues labeled with fluorescent dyes have been developed.

Due to the major importance of iron in a wide variety of cellular processes, and the harm caused by its uncontrolled accumulation in the body, its uptake and storage is strictly regulated.

Copper is an essential cofactor for enzymes involved in diverse cellular processes, including oxidative metabolism, neurotransmitter synthesis, free radical detoxification, and iron uptake.

After graduating, Clara moved to the UK to work as a Research fellow with Prof John Findlay at the University of Leeds, working mainly with Lipocalins and their cellular receptors, identifying structural binding / transport motifs and investigating the physiological link between vitamin A uptake and Type 2 Diabetes.

«That issue starts at the cellular - molecular level, with the actual testing and the understanding that biologists have of the pathology of colorectal cancer and diagnosis of colorectal cancer, all the way to the community uptake of that screening.»

Testosterone stimulates cellular amino acid uptake and protein synthesis in muscles by interacting with the DNA, as well as increasing muscle fiber site neurotransmitters.

Testosterone stimulates growth hormone responses that enhance skeletal muscle cellular amino acid uptake

Insulin binds to many cells in the body having appropriate receptors for the peptide hormone and causes a general uptake in cellular glucose.

A second set of cellular level events involves uptake of iodine into thyroid cells by a protein referred to as the sodium - iodide symporter (and abbreviated as «NIS,» where the «N» comes from «Na,» which is the scientific abbreviation for the element sodium).

A person may feel unwell initially on this type of diet but the all important uptake of potassium will slowly improve at the cellular level.

Twelve - hour exposure of 3T3 - L1 adipocytes to H (2) O (2) or TNF - alpha resulted in the increase of c - Jun NH (2)- terminal kinase (JNK) activation and insulin receptor substrate 1 (IRS1) serine 307 phosphorylation, concomitantly with the decrease in insulin - stimulated IRS1 tyrosine phosphorylation and cellular glucose uptake.

PEMF uses electrical energy to direct a series of magnetic pulses through injured tissue, and each magnetic pulse induces a tiny electrical signal that stimulates cellular repair by upregulating a tissue repair protein called «heat shock protein» and also by increasing the uptake of oxygen and nutrients into tissue.

The rapid repetitive contractions occur all the way down to the cellular level, causing a more permeable cellular wall allowing increased uptake of oxygen and nutrients.