Sentences with phrase «normal cell metabolism»

Positive effects where ROS mediate functions of normal cell metabolism include the induction of host defence genes and mobilisation of ion transport systems, and roles in redox signaling.

Oxidative stress reflects an imbalance between the reactive oxygen that is generated by normal cell metabolism and the cell's ability to handle toxic byproducts from that metabolism.

Not exact matches

Phosphorus contributes to normal energy - yielding metabolism, function of cell membranes and contributes to the maintenance of normal teeth and bone.

Manganese is an essential trace metal that is crucial for normal cell function and metabolism and is particularly important for brain health.

Carcinogens may cause cancer by altering cellular metabolism or damaging DNA directly in cells, which interferes with normal biological processes.

The hope is that 3BP specifically kills certain cancer cells — while leaving normal cells alone — because they rely more on glucose metabolism than on an alternative pathway called oxidative phosphorylation.

The metabolism of bone cells determines how much sugar they use; if the bone cells consume more sugar than normal, this can lower the glucose level in the blood.

Calcium, however, puts a strain on cells — it is known to hinder protein - folding and metabolism when it accumulates — disrupting normal cellular function.

One possibility for how that happens, says Hekimi, is that slow cellular metabolism delays the normal buildup of metabolic byproducts, such as reactive compounds known as free radicals, that are toxic to cells.

«We know that the pathway is important for normal cells to carry their activities as it is involved in regulating metabolism, that is, how cells process nutrients to obtain energy and how cells use energy to grow.

«Oxygen by - products produced during normal metabolism can cause oxidative damage to biomolecules in cells, such as DNA and RNA,» explains Jian - Ping Cai, a researcher involved in the study.

The compound increases bone mass by protecting and increasing the activity of bone cells in various stages of normal bone mantanence, utilizing mechanisms that overlap those that regulate whole - body energy metabolism.

Further research showed that the WWOX gene plays a role in the altered metabolism of cancer cells which are known to use glucose differently to normal cells.

«This difference in metabolism is a key part of how cancer cells have a competitive advantage over normal cells.

Sphingomyelinases like nSMase2 play a normal role in the cell's metabolism by breaking down fatty molecules into smaller components that cells use for every day functions.

The cells, which also expressed lower levels of genes involved in normal cellular metabolism, were evenly distributed throughout the liver's lobules.

The authors suspect that methylation inhibits the ability of the RXRα protein to play its normal role in the development and metabolism of fat cells, resulting in obesity.

When aSyn was produced at low levels, it made its way to the cell membrane and appeared to regulate chemical trafficking and metabolism of compounds called lipids — what may be normal functions for this protein.

Unlike the case of most gene therapies that are intended to permanently alter their target cells, however, Oisín's senoablative genetic constructs will not be inserted permanently into the patient's genome: instead, its genetic payload will be expressed temporarily from the main body of the cell, following which the construct will be passively degraded by normal cellular metabolism.

The proteins and other constituents of our cells are all eventually damaged as the result of biochemical accidents that occur during normal metabolism, or simply outlive their usefulness.

Autophagy eventually kills cells, so new therapies that deprive cells of nutrients or otherwise thwart metabolism will likely cause more harm to cancer cells than to normal cells.

Primary aging is what your body does to you even under the best of circumstances: cell and tissue damage that accumulates as a form of biological wear and tear, created as a result of the normal, healthy operation of metabolism.

Jared Mayers (Brigham and Women's Hospital Boston, USA), winner of the prize category Translational Medicine, kicked the event off with his research on differences in how cancer cells and normal cells utilize of nutrients and how this has been linked to genetic changes in cancer, opening up an opportunity for drugs targeting metabolism.

Free radicals are a normal by - product of metabolism, but they can damage healthy cells, leading to premature aging and serious health concerns like cancer and heart disease.

1) Phytonutrients: * Occur naturally in fruits and vegetables * Promote the function of the immune system * Help fight off viruses as well as reduce inflammation * Associated with the treatment and / or prevention of cancer and cardiovascular disease 2) Enzymes: * Responsible for metabolic processes that occur within a cell and are necessary for sustaining life * Assist and play a large role in digestion, energy production, blood coagulation and contraction of muscles 3) Amino Acids: * The basic building blocks of protein * Absorption of amino acids is essential for your metabolism 4) Essential Fatty Acids: * Reduce the risk of heart disease and some forms of cancer * Improve mood * Decrease inflammation 5) Vitamins: * Essential for the normal growth and development of all human beings * Healthy maintenance of cell tissues and organs * Help process proteins, carbohydrates and fats required for utilization 6 & 7) Macro and Trace Minerals: * Involved in electrolyte balance of body fluids * Essential for normal cellular activity * Provide hardness to bones and teeth

Molybdenum: This mineral is needed in small amounts for nitrogen metabolism, iron absorption, fat oxidation and normal cell function.

Vitamin B9, commonly known as folate, is needed to support a strong metabolism, healthy blood cells, and normal physical development.

Why you need it: plays a critical role in energy metabolism and is vital for the normal functioning of all body cells, especially nerves.

As a result, one could argue that things would run the opposite way than Adele proposes: reducing dietary glucose, which generally does not reduce blood glucose levels, will not affect cancer metabolism, but will limit availability of glucose to normal cells for structural use.

These fats get inside the cells, hardening them and preventing normal metabolism.

Coenzyme Q10 (CoQ10) is well known as a critical compound required by the body to facilitate normal breakdown of adenosine triphosphate (ATP) within each cell into energy we need for metabolism and life itself.

Several studies have shown that people with schizophrenia often have low levels of the particular EFAs necessary for normal nerve cell membrane metabolism.

Nerve cells depend on healthy membrane function for normal neurotransmitter metabolism and nerve signal transmission.

Cancer cells are known to have anywhere from ten to seventy times more insulin receptors than normal cells and depend upon anaerobic metabolism of sugar for fuel.

Tumor - bearing mice fed diets high in MCTs were found to have reduced levels of the enzyme fatty acid synthase and also reduced acetyl CoA, similar to tumor free mice, suggesting cancer cell metabolism was restored back to that of normal cells.94

Our cells are constantly forming toxins as normal waste products of metabolism.

* It is also a highly effective antioxidant that can protect the body's cells and molecules from damage by free radicals and reactive oxygen species generated during normal metabolism and exposure to environmental stressors.

* It is also a potent antioxidant that can protect the body's cells and molecules from damage by free radicals and reactive oxygen molecules generated during normal metabolism and typical environmental exposures.

* It is also a highly effective antioxidant that can protect the body's cells and molecules from damage by free radicals and reactive oxygen molecules generated during normal metabolism and exposure to environmental stressors.

ROS form as a natural byproduct of the normal metabolism of oxygen and have important roles in cell signaling.

Cancer cell metabolism is dependent upon methionine being present in the diet; whereas normal cells can grow on a methionine - free

Cancer cell metabolism is dependent upon methionine being present in the diet; whereas normal cells can grow on a methionine - free diet feeding off other sulfur - containing amino acids.

More recently, «studies have shown that D3 can help activate hair growth by similar means — boosting the metabolism of the follicles and encouraging those cells to turn over in a more normal way,» says Michelle Henry, MD, a dermatologist in New York City.

«With an underactive thyroid, the body compensates up to a point, but if the gland is unable to put out a normal amount of thyroid hormone, the body will slowly lose the ability to... create energy, not only for day - to - day activity, but also for the growth and metabolism of cells,» says Dr. Bernstein.

Once enough fat has accumulated in these liver cells to cause them to swell, they can no longer do their normal chores of protein synthesis, carbohydrate metabolism and detoxification of wastes.

«Cancer cells behave differently than normal cells in terms of glucose metabolism,» said Wisner.