The prize, considered among the most prestigious in the scientific community, recognizes Schreiber for his work in chemical biology and for the use of small molecules as probes to uncover
novel cellular mechanisms at the root of human health and disease.
Not exact matches
This is likely to be a
novel cellular defense
mechanism to prevent genetic mutations from being expressed.
What are the molecular and
cellular mechanisms by which patients with certain chronic diseases have increased or decreased risks for developing cancer, and can these connections be exploited to develop
novel preventive or therapeutic strategies?
The HFSP supports
novel, innovative and interdisciplinary basic research focused on the complex
mechanisms of living organisms; topics range from molecular and
cellular approaches to systems and cognitive neuroscience and the interactions between organisms.
The lab focuses on clarifying the
mechanisms of brain plasticity, gene expression, and responses of
cellular elements to different psychotropic drugs, and have identified several
novel brain sites and pathways that constitute attractive targets for new drug development.
We are interested in using
novel molecular and
cellular methods to study the pathogenic
mechanisms of lupus nephritis.
Dr. Gan and her team discovered new
cellular mechanisms that could lead to
novel approaches to remove toxic proteins from aging neurons.
These isogenic cell lines can be used not only to understand the
cellular consequences of disease mutations, but also to perform high throughput genetic and pharmacological screens to both understand the underlying pathological
mechanisms and to develop
novel therapeutic agents to prevent or treat such diseases.
Our work has given rise to
novel experimental results, which have helped to demonstrate the existence of bidirectional communication between astrocytes and neurons, the active participation of the astrocytes in neuronal physiology and synaptic transmission, and the
cellular and molecular
mechanisms involved.