It appears to reduce inflammation involved in cartilage degeneration and thus has a positive effect in canine
OA patients.
We investigated genes and pathways that mark OA progression in isolated primary chondrocytes taken from paired intact versus degraded articular cartilage samples across 38 patients undergoing joint replacement surgery (discovery cohort: 12 knee OA, replication cohorts: 17 knee OA, 9 hip
OA patients).
Researchers in New Zealand studied 206
OA patients for two years to measure the efficacy of adding regular physical exercise, manual therapy, or a combination of both therapies to standard care, versus continuing usual medical care for OA alone.
At baseline, the mean age of
the OA patients in the study was 66 years with a mean WOMAC score of 100.8.
Not exact matches
Through their analysis the researchers detected damaged proteins in characteristic patterns in the samples of those
patients with early and advanced
OA and RA, but were found at markedly lower levels in the samples of those in the control group — providing the researchers with the identifiable biomarkers necessary for early detection and diagnosis.
Patients with early - stage and advanced
OA, RA or other inflammatory joint disease were recruited for the study alongside a control group of those with good skeletal health, with plasma and synovial fluid samples from both groups being analysed using mass spectrometry.
Dr Tew, said: «Our research has the potential to identify different sub-groups of
patients, including those in the early stages of
OA, that could benefit from therapeutic interventions.
Investigators conducted a 5 - week effectiveness study of diclofenac topical gel, an NSAID, in 44
patients with knee
OA (i.e., arthritis caused by a breakdown of the lining of the joints).
Furthermore, Dr. Wasan said, «
Patients with neuropathic pain symptoms in
OA respond equally as well to topical NSAIDS as those who do not have neuropathic pain symptoms.»
Moving forward, the researchers conclude that asking older
patients suffering from
OA if they experience pain at these crucial moments, could be a way to screen people for risk of developing depression later on.
In conclusion, among
patients with symptomatic knee
OA, 2 years of intra-articular steroids resulted in more cartilage volume loss and no difference in knee symptoms.
In fact, in a 2013 study,
patients with
OA who got the procedure fared about the same as those who just did physical therapy (PT).
French studies found that avocado oil can relieve
OA pain; stimulate cartilage repair; and lower a
patient's need for non-steroidal anti-inflammatory drugs.
Second, review the health benefits of small weight losses with
patients, emphasizing the positive effects of reduced weight and exercise on
OA - symptoms such as pain.
It provides a way to address the chronic nature of
OA pain, and is especially helpful when the
patient is older and not able to take a NSAID.
The following supportive care options apply to most canine
patients with the chronic pain of
OA:
The goal of dog medicine in pain management, such as when managing canine Osteoarthritis (
OA) is to reduce clinical signs, slow the progression of the disease, and to improve the comfort of the
patient.