Sentences with phrase «of amyloidosis include»
OTHER TYPES OF AMYLOIDOSIS include localized amyloid, b2 micro globulin amyloid, and Alzheimer's disease.
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Payne keyed in the symptoms, and the computer program suggested a handful of potential conditions, including a rare disease called amyloidosis, in which abnormal proteins build up in the body, interfering with normal organ function and causing nerve damage.
Indeed, a series of recent, exciting studies have shown that the pathologic hallmarks of various PMDs, including Alzheimer's, Parkinson's, Huntington's diseases, and some forms of systemic amyloidosis, can be induced under experimental conditions by administration of tissue homogenates carrying the respective misfolded proteins (Xing et al., 2001; Lundmark et al., 2002; Meyer - Luehmann et al., 2006; Clavaguera et al., 2009; Ren et al., 2009; Eisele et al., 2010; Grad et al., 2011; Luk et al., 2012; Morales et al., 2012; Mougenot et al., 2012; Stöhr et al., 2012; Iba et al., 2013).
Accumulation of misfolded protein aggregates is not only present in T2D but also is the main feature of a group of diseases known as protein misfolding disorders (PMDs), including various neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, and prion disorders, as well as several systemic amyloidosis disease (Luheshi et al., 2008; Soto and Estrada, 2008).
Amyloidosis involves the extracellular deposition of proteinaceous amyloid fibrils and accessory molecules in organ (s) and / or tissue (s), and is associated with a host of human diseases, including Alzheimer disease, diabetes, and heart disease.
The company's antibody - based product candidates target a number of potential indications including AL and AA forms of amyloidosis, Parkinson's disease and other related synucleinopathies and novel cell adhesion targets involved in inflammatory diseases and cancers.
Some of the conditions to which this breed is prone include entropion, swollen hocks syndrome, amyloidosis, and more.