Sentences with phrase «observing inflammatory cells»
«Observing inflammatory cells in the body: Researchers develop a new method that enables them to genetically modify immune cells, multiply them and visualize them in living organisms.»
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The team led by Professor Bozec turned off the oxygen sensor HIF in B cells and observed that this prevented the resolution of inflammation, leading to chronic inflammatory diseases.
In fact, when the researchers inhibited the secreted factor related to the activity of inflammatory cells, they observed a decrease in the proliferation of cancer cells.
The authors observed an inflammatory response in two patients who had mutated versions of SKIV2L, suggesting that SKIV2L keeps inflammation in check in human cells, too.
Researchers observed that the immune cells, called CD4 T - cells, in the airways of severe asthmatics secreted different inflammatory proteins than those in mild disease, particularly interferon gamma.
Perivascular and peribronchial inflammatory infiltrates were observed in most fields along with desquamation of the bronchial epithelium, collections of edema fluid, sloughed epithelial cells, inflammatory cells and cellular debris in the bronchial lumen.
Interestingly, RIPK2 has been demonstrated to be involved in the active growth of CD90 (+) intestinal stromal cells to suggest an «inflammatory» cross-talk between intestinal stromal cells and the epithelial cells (Owens et al., 2013), and we can observe robust activation of RIPK2 in IBD colon tissue sections immunostained with our proprietary pY474 RIPK2 antibody (Salla et al., unpublished observations).
More specifically, epigenetic programming of cells would allow them to show more pronounced inflammatory responses when exposed to challenge (Miller et al., 2011a), an effect that has been observed in primate models (Cole et al., 2012), as well as in humans (Irwin and Cole, 2011).