Sentences with phrase «olaparib blocks»
Olaparib blocks this second repair pathway by inhibiting an enzyme called poly ADP ribose polymerase (PARP).
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PARP (Poly ADP - Ribose Polymerase) inhibitors, such as olaparib, are targeted drugs that block an enzyme involved in many functions in the cell, including the repair of DNA damage.
The trial compared the activity of the combination of the drug olaparib, which blocks DNA repair, and the blood vessel inhibitor drug cediranib, vs. olaparib alone.