Sentences with phrase «optical tweezers»

My idea was to use two optical tweezers introduced into an optical microscope to grab the plastic handles glued to the ends of the molecule.

«AFM is limited to surfaces, so the idea was why not take optical tweezers and replace the tip with a particle and probe the cell from the inside,» explains Florin.

«First, JPK users can already study materials over a broad range of forces, from piconewton levels with optical tweezers (NanoTracker ™) through conventional AFM imaging & force spectroscopy (NanoWizard ®, CellHesion ® and ForceRobot ®) to the low nanonewton range.

Bundles are polymerized from the surface of mDia1 - coated latex beads, and deformed by manipulating both ends through attached beads held by optical tweezers, allowing us to record the applied force.

His research over the last 25 years has focused on the development and application of new scanning probe microscopes, including the invention of two new types of high - speed AFM and the use of nanotools controlled by holographic optical tweezers to act as a new type of AFM probe.

Optical tweezers harness the tiny forces exerted by incident light to trap and manipulate nanoparticles, but the inevitable laser heating leads to radiation forces that reduce the trap stability.

The methodology has been applied to the study of lactose repressor protein (LacI), fluorescently labeled with Atto532, and detected as it binds to a DNA molecule (trapped between two optical tweezers) containing specific LacI binding sequences (i.e., operators).

DEP can be thought of as a low - frequency analogue of optical tweezers, and it has become a popular technique in the microfluidics and lab - on - a-chip fields because it is so simple.

Under - filling trapping objectives optimizes the use of the available laser power in optical tweezers.

Anastasiya Trushko (Howard, MPG)-- «Interaction of XMAP215 with a microtubule plus - end studied with optical tweezers» (2012)

Mohammed Mahamdeh (Schaeffer, TUD)-- «High Resolution Optical Tweezers Optimized for Biological Studies» (2011)

Volker Bormuth (Howard, MPG)-- «Optimized optical tweezers to study the mechanics of kinesin - 8: stepping, slipping, protein friction» (2009)

For work on optical tweezers for biological applications which use focused laser light to trap and manipulate virus particles, living cells and other biological entities whilst allowing them to maintain viability.

Her current research interests include holographic optical tweezers, digital holographic microscopy and linear and non-linear Raman microscopy.

Optical tweezers that can move particles a few millimeters are common.

Other instrumentation that we develop are optical tweezers (photonic forces), atomic force microscopy, and total - internal reflectance fluorescence microscopy.

Andrei Rode, a researcher involved with the project, said that existing optical tweezers are able to move particles the size of a bacterium a few millimeters in a liquid.

At the same time, cultivating an ethos of invention and discovery enables us to translate research into possibilities for tomorrow, from new tools for scientific inquiry like optical tweezers and lasers to new ways of producing sustainable, eco-friendly energy.

«Laser optical tweezers reveal how malaria parasites infect red blood cells.»

The gradient optical force was first used in the 1970s, in «optical tweezers,» which were designed to manipulate molecules in a kind of optical microscope.

The researchers used optical tweezers to pick up individual parasites that had just emerged from a red blood cell and deliver them to another red blood cell, demonstrating that the technique is suitable for studying the invasion process.

«Optical tweezers can do this to some extent but suffer from heating of the sample.»

Genmiao M. Wang of the Australian National University and colleagues discovered the anomaly when they dragged a micron - sized bead through a container of water using optical tweezers.

Using these so - called optical tweezers, for example, biologists have been able to probe viruses, cells, bacteria, and DNA.

On an even smaller scale, Spudich, Steve Kron, Elizabeth Sunderman, Steve Quake and I are manipulating a single DNA molecule by attaching polystyrene spheres to the ends of a strand of DNA and holding the spheres with two optical tweezers.

The great advantage of using a single beam is that it can be used as an optical tweezers to manipulate small particles.

In addition, we have devised an «optical tweezers» that uses laser beams to hold and move organelles inside of cells without puncturing the intervening membranes.

Optical tweezers can be used to examine even smaller biological systems.

We are probing this «molecular motor» by attaching a polystyrene sphere to an actin filament and using the optical tweezers to grab onto the bead.

The ability to trap live organisms without harm is surprising, considering that the typical laser intensity at the focal point of the optical tweezers is about 10 million watts per square centimeter.

A feedback circuit then directs the optical tweezers to pull against the myosin in order to counteract any motion.

One application of the optical tweezers, discovered by Dziedzic and Ashkin, has captured the imagination of biologists.

Current methods for doing this involve directly probing cells with expensive instruments, such as atomic force microscopes and optical tweezers, which make direct, invasive contact with the cells.

One potential application is in the realm of molecular manipulation and optical tweezers, which use light to move molecules.

Since the 1980s, scientists have pulled small objects around using so - called optical tweezers, which can grab hold of tiny objects such as cells and pull them around.

They then dragged each bead across a cell using optical tweezers, a technique that employs a highly focused laser beam to physically move microscopic objects.

This image depicts a single cell experiment in which a human neutrophil was picked up by a micropipette (top panel) and brought into close contact with S. Typhimurium cells immobilized by optical tweezers.

The method combines two high - tech laboratory techniques and allows the researchers to precisely poke holes on the surface of a single cell with a high - powered «femtosecond» laser and then gently tug a piece of DNA through it using «optical tweezers,» which draw on the electromagnetic field of another laser.

To manipulate the foreign DNA, the scientists used optical tweezers, which essentially tweaks a laser beam whose electromagnetic field can grab hold of and transport a plasmid - coated particle.

In the model microscopic system developed by scientists from Bristol, Düsseldorf, Mainz, Princeton and Santa Barbara, a ring of colloidal particles are localised in optical tweezers and automatically translated on a circular path, transferring a rotational motion to an assembly of identical colloids confined to the interior region.

Such manipulations are routinely done with real atoms trapped in spots of laser light and tugged about with «optical tweezers.»

Optical tweezers work thanks to the force generated when a particle refracts light, which pushes the object to the most intense part of a beam.

BEAMS of electrons can pick up and move tiny objects, just like optical tweezers that manipulate items using light.

Researchers could also use optical tweezers to construct molecules with specific quantum properties, says study coauthor Kang - Kuen Ni, a chemist at Harvard University.

The condensate, which is made from around 4000 cooled rubidium atoms, is trapped inside the beams by the same forces used to create optical tweezers, which can manipulate particles on a small scale.

«Generally, most existing techniques to look at single - molecule movements — such as optical tweezers — have a resolution, at best, of about 300 picometers,» said Gundlach.

Take optical tweezers, a pioneering device developed in 1986 by a team at Bell Labs in Holmdel, New Jersey, that included the 1997 Nobel laureate and now US energy secretary Steven Chu.

Not exact matches

The new tweezers have a resolution and sensitivity 1000 times finer than optical techniques.

Also vital to the work is optical (laser) tweezers, which manipulate objects at the molecular level.

These twisted beams of light are useful in nanotechnology, as optical «tweezers» or «spanners» to manipulate tiny particles.