Blocking IL - 15 or IL - 15 signaling may be a way to restore
oral tolerance to gluten and allow effective responses to vaccines aimed at preventing
development of celiac disease, Jabri said.
Another potential mechanism through which iodine exacerbates or induces Hashimoto's is by up - regulating Th17 cells, the immune cell subset responsible for tissue destruction in autoimmune disease, and by suppressing
development of regulatory T cells, the population that invokes
oral tolerance to arrest autoimmune responses (31).