Sentences with phrase «osteocalcin from»
Osteocalcin from the bones of pregnant mice can penetrate the placenta and help shape fetal brain development, Karsenty and colleagues reported in 2013 in Cell.
https://www.sciencenews.org/ Not exact matches
Osteoblasts taken from the osteocalcin - deficient mice, however, had no impact.
This is explained by another finding from the Karsenty lab: circulating levels of osteocalcin are much higher in younger mice than in older mice.
In postmenopausal American women in the Framingham Offspring Study, for example, which did not account for whether anyone was supplementing with vitamin K, undercarboxylated osteocalcin ranged from zero to 91 percent, and averaged 17 percent.
For example, both increasing or decreasing the rate of bone resorption affects energy balance and testosterone, apparently via undercarboxylated osteocalcin, showing that departures from «normal» in both directions are effective, and thus that «normal» is within the effective range.
* Oddly enough, however, the experiments with fresh pancreatic islets and fat cells taken from the mice suggested that the positive effects of uncarboxylated osteocalcin on insulin only occurred at concentrations extremely low compared to those of undercarboxylated osteocalcin normally present in mice, while the effects on adiponectin and energy expenditure only occurred at normal to high concentrations.
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