Not exact matches
«This fact,» says Panowski, «suggests that pha - 4 [protein] and daf - 16 may be competing in some way, perhaps
for target genes that increase longevity or
other coregulators or
cofactors that may be required
for this.»
It could be that IGF - 1 still matters while a person already has cancer regardless of vitamin d or any of its
other cofactors, but the evidence
for a causal relationship between serum IGF - 1 and incidence of cancers in the presence of good control
for IGF - 1 receptors has been called into question and is supported by well - known mechanisms.
The reduction of so many
cofactors like TMA, and dietary AGEs heterocyclic amines as well as a host of
other other inflammatory factors might well ameliorate the need
for statins.
There is no one
cofactor, or set of
cofactors that optimally define value, if
for no
other reason than the accounting rules keep changing.