Sentences with phrase «other gene abnormalities»

Other gene abnormalities were, on the other hand, encountered in the other groups, such as c - Kit [19], cyclin - dependent kinase 4 (CDK4) and cyclin D1 (CCDN1)[20, 21].

Not exact matches

Mutation around the region of the human SOX9 gene, which encodes the Sox9 protein, causes campomelic dysplasia, a congenital disease that is accompanied by skeletal abnormalities and other conditions.

On the other end of the spectrum are Mendelian diseases such as cystic fibrosis and sickle - cell anemia, which are caused by abnormalities to a single gene.

And an incidental finding of a gene mutation or other abnormality may not always lead to a particular disease.

Mice carrying a mutated copy of the gene have 10-fold fewer neurons and other brain abnormalities, a new study suggests.

Multiple mutations in DNA — specifically, abnormalities in the p21 and p53 genes, among other changes — stop the process of apoptosis, or programmed cell death, that normal cells undergo.

Exactly how histamine abnormalities would contribute to the symptoms of Tourette syndrome isn't clear, but State notes that knocking out the equivalent of the HDC gene makes mice more prone to head bobbing, spinning, and other repetitive behaviors.

In these tests, StemFit not only delivered higher cell proliferation, but also showed characteristics such as homogeneity of gene expression compared with iPS cells cultured with four other media without any chromosomal abnormalities.

The short form of the serotonin transporter gene promoter does not explain autism, insists Dr. Cook, who heads a nationwide consortium of researchers looking for the genetic underpinnings of this disease, but it does appear to play a significant role, perhaps in concert with other abnormalities which we've not yet uncovered.

PHILADELPHIA — Knocking out one or both crucial regulatory genes caused cleft lip, skin barrier defects, and a host of other developmental problems in mice, according to new research from the Perelman School of Medicine at the University of Pennsylvania, hinting that abnormalities in these molecular pathways could underlie many birth defects that are presently not well understood.

Other studies cited by the article found that the merle gene was associated with skeletal, cardiac and reproductive abnormalities, but there is far less conclusive evidence for this.