Sentences with phrase «other immune therapies»

They are investigating bacteria that could influence other immune therapies, such at the CTLA - 4 pathway, exploited by ipilimumab.

They are investigating other bacteria that could influence other immune therapies, such at the CTLA - 4 pathway, exploited by ipilimumab.

Other immune therapies based on antibodies have also produced impressive outcomes in recent years.

Not exact matches

One setback for these therapies which use the body's immune system to fight cancers is that they are, at times, more effective in certain patient pools than others.

Side effects of the treatment included skin rashes, thyroid problems and diarrhea as the therapy caused the immune system to attack other parts of the body.

Because the CAR - T cells do not eradicate all cancer cells, the researchers think the immune therapy will need to be combined with other treatments.

«The findings also suggest that therapies targeting the immune system may be effective treatments against this disorder and possibly other forms of epilepsy,» said Nath.

«It is anticipated that this novel compound will have significant efficacy in human melanomas and other cancers either as a stand - alone therapy or in combination with other targeted or immune - based therapies,» explained co-corresponding author Rhoda Alani, MD, the Herbert Mescon Chair of Dermatology at Boston University School of Medicine (BUSM).

«Our study reveals a new mechanism that could be harnessed for biological therapies for lupus and other autoimmune diseases, where the immune system mistakenly targets the body's own cells,» says senior study author Boris Reizis, PhD, professor of Pathology and Medicine at NYU Langone.

«It is expected that this study will lay the foundation for developing a new class of potent and effective cancer therapies and the development of reagents targeting epigenetic events in immune - mediated diseases as well as other epigenetically - influenced diseases,» said Alani, who also is chief of dermatology at Boston Medical Center.

Hortense Dodo, a food molecular biologist on the team, says other attempts to solve the problem, such as immune therapy or vaccines, have failed so far (but see ScienceNOW, 10 March).

However, ChABC gene therapy decreased the presence of these cells and increased the presence of other immune cells called M2 macrophages that help to reduce inflammation and enhance tissue repair.

Patients undergoing this viral therapy typically experience mild flulike symptoms, owing to immune response to the virus, Kirn said, but the company has reported no other side effects.

Other experts say the method could help induce the immune system to tolerate other gene therapy agents beside adenovOther experts say the method could help induce the immune system to tolerate other gene therapy agents beside adenovother gene therapy agents beside adenovirus.

Enhancing such an interaction, perhaps in combination with other therapies that attack the virus at other stages of its life cycle, could give the immune system the opening it needs to overcome an infection.

The ability of these children to maintain an intact immune system in the face of ongoing viral replication and in the absence of antiretroviral therapy can provide us with new insights into hitherto unknown defense mechanisms, which could eventually benefit other HIV patients,» says Professor Oliver T. Keppler, Chair of Virology at the Pettenkofer Institute, and former head of the German Reference Center for Retroviruses in Frankfurt am Main.

The proposed clinical trial, in which researchers would use CRISPR to engineer immune cells to fight cancer, won approval from the Recombinant DNA Advisory Committee (RAC) at the U.S. National Institutes of Health, a panel that has traditionally vetted the safety and ethics of gene therapy trials funded by the U.S. government and others.

Inhibitory control Other strategies being pursued to prevent the formation of inhibitors of clotting - factor therapy include immunosuppressants and drugs that deplete specific immune cells.

Independent studies by Hortelano's group and other research teams in Germany and the United States have shown that this oral gene therapy does not activate the immune system.

Current therapies to treat pathological inflammation generally focus on quieting the overactive immune response, but in suppressing the immune system, patients are vulnerable to severe infections arising from other sources.

«While there is understandable excitement around new therapies that enlist the immune system to fight cancer, we are still in a situation where greater than half of patients don't respond in melanoma and the response rate is even worse in other cancer types,» Hanks said.

The findings have implications for all aspects of medical and scientific research because laboratory mice underpin studies whose results have a transformative effect on human and animal lives through vaccination and other immune - based therapies.

These are skills that we implement for other international trials of gene therapy for rare genetic diseases of the immune system, blood, muscle, vision or liver... We will continue the current study with the objective of providing treatment for patients.»

«It is quite possible that by increasing the immune function in patients they will also respond better to some other therapies.»

In further studies, they plan to explore the role of autophagy in immune reactions toward other tumor cell types, to determine whether such therapies might be effective in a broad range of cancers.

Other blood disorders that have shown significant benefit from targeted gene therapy in small trials include hemophilia (specifically, factor IX deficiency), severe beta - thalassemia (deficiency for the adult beta - globin gene) and leukemia, where the patient's immune cells were treated to enable them to recognize cancer cells and destroy them.

Other research at U-M is developing new options for treating brain cancer through immunotherapy — harnessing the immune system to attack cancer cells once an injection of a particular gene therapy is delivered into the brain tumor.

Through strategic partnerships with industry and nonprofit organizations, we gain access to a portfolio of priority drugs for testing within our expert focus groups, including checkpoint inhibitors, therapeutic vaccines, innate immune stimulants, targeted therapies, and many other promising treatments and technologies with high therapeutic potential.

The researchers tested whether stromal tumor infiltrating lymphocytes (TILs) and other immune cells might predict responses to therapy in a set of 30 HER2 - positive breast cancer tissues treated with TCHP (26 patients) or with TCH without pertuzumab (4 patients).

The third one is that you can get memory and that's the hallmark of the immune system that doesn't exist for any other type of cancer therapy.

These include therapies that target other immune checkpoint receptors such as Tim3 and Lag3 (2) or other inhibitory receptors including the adenosine 2A receptor, PGE2 receptor, and TGF - β receptor complex (7, 8).

This novel approach, which reveals complex interactions between cells and proteins, can also be used for other diseases to generate new knowledge about the regulation and dysregulation of the immune system, which can eventually give rise to new, improved immunological therapies.

The long - term vision is to apply these technologies to other genetic diseases, such as sickle cell disease, and to explore applications in developing effective immune therapies for cancer.

Patients suffering with chronic inflammatory diseases, recurrent infection, autoimmune diseases and other disorders of aging have also found promise in immune regenerative therapies.

These therapies use non-specific molecules that do not affect the cancer directly, but send signals that stimulate other cells of the immune system to fight against cancer cells.

The results of her project will help scientists develop novel therapies to target the regulatory proteins that cause CD47 overproduction in leukemia and other cancer stem cells, with the goal of restoring immunosurveillance and enabling the immune system to recognize and destroy these aberrant cancer cells.

The gift allowed Memorial Sloan Kettering to establish a state - of - the - art collaborative research center focused on immune - system - based therapy, an approach showing great promise in the treatment of cancer and several other diseases.

«We anticipate,» says Dr. Chou, «that this research will provide important pre-clinical data to support clinical trials using DAC and similar drugs combined with immune therapies targeting antigens like NY - ESO - 1 to treat advanced colorectal cancer and potentially other common cancers.»

In the case of CAR T cell therapy — which re-educates immune cells to attack blood cancers and other diseases — dozens of researchers and physicians throughout City of Hope contribute to its momentum.

Novel immune therapies for prostate and pancreatic cancers, among others, are also in clinical study.

In the future, scientists may be able to modify human stem cell lines in the laboratory by using gene therapy or other techniques to overcome this immune rejection.

Although there is a tendency towards a decrease in late twenties and early thirties, according to the Medical Center of the University of Maryland, even the older generation are not completely immune because acne can occur at any period of life, as a result of poor hygiene, stress, as part of other diseases or therapies with individual drugs, but also as a result of inadequate nutrition and a healthy diet.

In variations, the method 100 can be used to promote targeted therapies to subjects suffering from an autoimmune condition, disorder, or adverse state, wherein the autoimmune condition produces systemic effects in terms of one or more of: immune response, respiratory function, musculoskeletal function, gastrointestinal function, circulatory system function, endocrine system function, and any other suitable physiological or behavioral function.

If we can starve and deplete cancer cells of energy, then in effect we can arrest their growth, spread, and even give the immune system and other therapies a better chance to kill them.

-- The life's work of Dr. John F. Prudden showed that bovine tracheal cartilage had unique and powerful effects on wound healing, immune conditions, joint health and other conditions considered to be treatment resistant to conventional therapies.

Some of these treatments such as Gerson Therapy work to strengthen and balance the immune system and take some time to be effective while other treatments, such as High Dose Vitamin C intravenous therapy, target cancer cells safely and work right away to decrease tumor load, allowing time for the nutritional program tTherapy work to strengthen and balance the immune system and take some time to be effective while other treatments, such as High Dose Vitamin C intravenous therapy, target cancer cells safely and work right away to decrease tumor load, allowing time for the nutritional program ttherapy, target cancer cells safely and work right away to decrease tumor load, allowing time for the nutritional program to work.

He offers concrete ideas for protecting young immune systems through diet and other natural therapies, in addition to exercising your freedom to nurture the health of your children, as you see fit.

Other examples of widely practiced nutritional therapies: drinking green tea to strengthen the immune system, eliminating dairy and / or sugar to reduce acne, and following an anti-inflammatory diet to manage conditions like arthritis.

IV hydration therapy has gained much popularity in the past few years in the treatment of «hangovers» but it has many other medical uses such as treating anemias, fatigue, immune disorders, neurological disorders, and metabolic diseases.

The New Arthritis Breakthrough: The Only Medical Therapy Clinically Proven to Produce Long - term Improvement and Remission of RA, Lupus, Juvenile RA, Fibromyalgia, Scleroderma, Spondyloarthropathy and other Forms of Arthritis by Henry Scammell gives a very clear and concise description of the Marshall Protocol, an antibiotic based relief program for auto - immune disease, which the book claims are in reality mycoplasma infestations.