Not exact matches
Novartis (nvs) chief Joe Jiminez has been touting a pricing model that incorporates drugs» real - world
outcomes for years, stressing the importance
of placing
patients before profits; Regeneron (regn) head honcho Len Schliefer had some tough words for fellow panelists
from Eli Lilly (lly) and Pfizer (pfe)(who argued that media reports about their own continued reliance on price increases to drive revenues is misleading) during Forbes» event.
To illustrate the issue, over the past 20 years, the cost
of a new drug per year
of a
patient's life has risen
from $ 50,000 to $ 250,000 after adjusting for inflation, according to Peter Bach, director
of the Center for Health Policy and
Outcomes at Memorial Sloan Kettering, who also spoke at the conference.
Once she can start aggregating data
from her
patients with data
from other doctors who are using the app, she will have a huge number
of data points that she can use to track everything
from the efficacy
of the surgery in certain
patient populations, to which doctors might get the best
outcomes.
We aim to shift the digital health dialogue
from one focused primarily on the degree
of investment and future expectations to one about digital health's effect on
patients and healthcare
outcomes.
The debate among politicians has shifted to now focus on doctors intimidation and away
from the focus on
patient outcomes that dominated the debate during the 2010 Fall session
of the Assembly.
We compared
outcomes after medical versus surgical management
of biliary tract disease in pregnant
patients.We reviewed the clinical course
of patients with symptomatic cholelithiasis during pregnancy
from 1992 to 2002 at two university hospitals.Seventy - six women with 78 pregnancies were admitted with biliary tract disease.
Future resources
from the NCI Center for Cancer Genomics (CCG), which oversees TCGA and other activities, will support more translationally focused research, including databases with genomic information on clinical samples linked to
outcomes of their
patient donors.
Funded by a $ 12 million grant, the FORCE - TJR research program has developed a national database
of surgical results and
patient - reported
outcomes from more than 30,000
patients.
Researchers reviewed data
from the Spine
Patients Outcomes Research Trial (SPORT) of 1,235 patients diagnosed with D
Patients Outcomes Research Trial (SPORT)
of 1,235
patients diagnosed with D
patients diagnosed with DS or SS.
Professor Voors concluded: «The major finding
from this substudy
of the RELAX - AHF trial is that diuretic resistance is a clinical problem that leads to worse in - hospital and early post-discharge clinical
outcomes in
patients with acute heart failure.
Based on these ex vivo experiments (in cells isolated
from patients and then exposed to PD - L1 blocking agents outside
of the body), they predict that when actual
patients are given PD - L1 blocking agents, their viral load at the time will influence the «net»
outcome, i.e., whether the blockage boosts or weakens the overall anti-HIV immune response.
«Although radiosurgery has been shown to be an effective post-surgical treatment for metastatic brain tumors, previous studies did not compare
patient outcomes from a single hospital over the same period
of time,» said N. Scott Litofsky, M.D., chief
of the Division
of Neurological Surgery at the MU School
of Medicine and senior author
of the study.
Under Litofsky's mentorship, Kristen Scheitler - Ring, a medical student doing a pathology fellowship at the MU School
of Medicine, studied the
outcomes of patients treated at MU Health Care
from 2010 to 2014.
Using data
from the Pediatric Health Information System database, a large, regionally diverse system, the researchers examined racial disparities in the treatment and
outcomes of hospitalized white and black pediatric
patients with moderate to severe Crohn's disease.
Researchers at Dana - Farber / Boston Children's Cancer and Blood Disorders Center report promising
outcomes from a clinical trial with
patients with a rare form
of bone marrow failure who received a hematopoietic stem cell transplant (HSCT) after pre-treatment with immunosuppressive drugs only.
The first results
from the European Cooperative Acute Stroke Study showed that treatment with a compound called alteplase between three and four and a half hours after the onset
of stroke improves the
outcome for
patients.
Our experience in performing kidney transplants
from living donors ensures the highest level
of care and better
outcomes for our
patients — both kidney donors and recipients.»
Researchers studied data
from 2,279 heart failure
patients in a trial called Heart Failure: A Controlled Trial Investigating
Outcomes of Exercise Training (HF - ACTION).
Researchers
from Massachusetts Eye and Ear / Harvard Medical School have found that
patients who were prescribed corticosteroids as part
of treatment for Lyme disease - associated facial paralysis had worse long - term
outcomes of regaining facial function than those who were prescribed antibiotic therapy alone.
Patients who didn't seek follow - up care within a month received the lowest rate of care and had the worst health outcomes — demonstrating the need to improve follow - up with high risk chest pain patients after they're discharged from the emergency room,
Patients who didn't seek follow - up care within a month received the lowest rate
of care and had the worst health
outcomes — demonstrating the need to improve follow - up with high risk chest pain
patients after they're discharged from the emergency room,
patients after they're discharged
from the emergency room, Ko said.
In an effort to reduce
patient misdiagnoses and associated poor patient outcomes from lack of prompt treatment, a Johns Hopkins Armstrong Institute for Patient Safety and Quality researcher is helping to lead the way in providing hospitals a new approach to quantify and monitor diagnostic errors in their quality improvement e
patient misdiagnoses and associated poor
patient outcomes from lack of prompt treatment, a Johns Hopkins Armstrong Institute for Patient Safety and Quality researcher is helping to lead the way in providing hospitals a new approach to quantify and monitor diagnostic errors in their quality improvement e
patient outcomes from lack
of prompt treatment, a Johns Hopkins Armstrong Institute for
Patient Safety and Quality researcher is helping to lead the way in providing hospitals a new approach to quantify and monitor diagnostic errors in their quality improvement e
Patient Safety and Quality researcher is helping to lead the way in providing hospitals a new approach to quantify and monitor diagnostic errors in their quality improvement efforts.
«We're trying to find better prognostic indicators
of outcomes so that only
patients who will benefit
from additional therapy receive it.»
The study, entitled COMET (Comparison
of Operative to Medical Endocrine Therapy) for low - risk ductal carcinoma in situ, received funding through a $ 13.4 million, five - year award
from the
Patient - Centered
Outcomes Research Institute (PCORI), an independent, nonprofit organization authorized by Congress in 2010 to support research that enlightens health care decisions.
The combination
of the two drugs could potentially shorten treatment time, reduce the side effects
of bedaquiline and improve
patient outcomes for those suffering
from TB.
The study, Developing an Interventional Stroke Service: Improving Clinical
Outcomes and Reducing Cost and Delivering Great Cost Savings Benefits to Health Economy, conducted at the University Hospital
of North Midlands, Stoke - on - Trent, U.K., found that mechanical thrombectomy (the use
of a device to retrieve a clot
from the vessel) in the treatment
of stroke reduced the average stroke
patient's hospital stay to 14 days when compared to previously recorded 90 days.
Dr. Grant and colleagues also performed a separate analysis
of data
from eight studies — including 838
patients — assessing nausea and vomiting as the main
outcome of interest.
Patients who sustain severe head injuries tend to have better
outcomes if they are taken to a designated trauma center, but 44 percent
of them are first taken to hospitals without these specialized care capabilities, according to new research
from the Perelman School
of Medicine at the University
of Pennsylvania.
The study did not have information on
outcomes of the ambulance calls or detailed information on
patients, so researchers could not differentiate events related to smoking or secondhand smoke
from other emergencies.
Analysis
of data
from nine randomised trials involving 6756
patients (1729 older than 80 years
of age) showed that alteplase treatment significantly increased the odds
of a good stroke
outcome (no significant disability 3 - 6 months after stroke), with faster treatment offering the best chance
of recovery.
The researchers next will turn to analyzing the presence
of myoferlin in samples
from numerous human tumor types available in an Ohio State tissue bank, which will allow them to compare protein levels in tumors to clinical
outcomes for the
patients who provided the samples.
In the study, researchers
from Kansas City VA Medical Centre in Kansas City, USA, examined the effect
of TRT on cardiovascular
outcomes by comparing incidents
of heart attack, stroke, and all - cause mortality among different sub-populations
of treated and untreated
patients.
In the present study, performed by Prof. Latzer who is also the director
of the Eating Disorders Clinic at Rambam Medical Center, the research student Adit Zohr - Beja, and Dr. Eitan Gur
from the Eating Disorders Department, Sheba Medical Center, Tel Hashomer, the researchers sought to examine claims concerning the ineffectiveness
of involuntary hospitalization and examined whether there is a difference in
outcome between
patients in extreme condition who were forcibly hospitalized and those who were hospitalized willingly.
Calibration is the agreement between the predicted risk and actual
outcomes on average, and across the spectrum
of predicted risk —
from low to high, said Mark E. Cohen, PhD, one
of the study's authors and a statistical manager in the ACS Division
of Research and Optimal
Patient Care.
Two drugs taken together can sometimes lead to
outcomes that largely deviate
from the effect
of the separated compounds — a fact well known
from warnings on
patient information leaflets.
Further research incorporating
patient outcomes and data
from actual clinical interactions is warranted to clarify the effect
of clinician implicit bias on the provision
of health care and
outcomes,» the study concludes.
The combined plunge in these feared
outcomes,
from 42 percent
of patients to 22 percent, represents the biggest improvement seen in any stroke - treatment trial to date, said Albers.
Michelle Hladunewich, MD (Sunnybrook Health Sciences Centre, in Toronto) and her colleagues assessed the effects
of such intensive dialysis on pregnancy
outcomes by comparing
patients from Toronto with that
from the United States.
Maybe in addition to collecting
outcomes from the individual
patients in the trial, you could collect
outcomes from members
of that
patient's community.
The study is investigator led and has therefore focused on clinical need, targeting
patients with progressive multiple sclerosis in whom most disability is incurred... The study also reports a predominant effect on neurodegenerative rather than inflammatory
outcomes, suggesting a novel mechanism
of action that might be suitable as combination treatment with immunomodulatory treatments... Further phase 3 studies to measure the effect
of simvastatin on sustained disability, particularly in
patients with non-relapsing secondary progressive and primary progressive multiple sclerosis, are clearly needed, but this trial represents a promising point
from which to develop trials
of progressive disease.»
To investigate, Csaba Kovesdy, MD (Memphis VA Medical Center and the University
of Tennessee Health Science Center) and his colleagues examined information
from the national VA research database and looked for associations between blood pressure and various clinical
outcomes — coronary heart disease, stroke, kidney failure, and death — in more than 300,000
patients with CKD.
Since blood samples are taken and frozen with many clinical trials, this allows them «almost a bit
of a time machine» to go back and explore questions around pain or neuropathy to run tests on neurons created
from blood samples
of patients taken in past clinical trials where responses and
outcomes have already been recorded.»
Therefore,
patients are benefiting
from more extensive repair
of aortic dissection, which may lead to improved long - term
outcomes.»
President
of ESTRO, Professor Vincenzo Valentini, a radiation oncologist at the Policlinico Universitario A. Gemelli, Rome, Italy, said: «This study not only shows a better
outcome for the women treated with IMRT, but has an additional value in defining the selection criteria for providing treatment to those
patients who will benefit
from new frontline technologies.
«We report that PD - L1 is expressed in 20 %
of malignant pleural mesothelioma
patients and is associated with poor
outcome, which suggests that this pathway could be targeted with PD - 1 / PD - L1 inhibitors,» says study author Dr Susana Cedres,
from Vall d'Hebron Institute Oncology, Barcelona, Spain.
Over an 18 - month period, Walvekar examined the
outcomes of 10
patients who underwent open retro - auricular thyroidectomy with a slightly modified incision
from the original technique.
Favourable
outcomes, ranging
from moderate disability to good recovery, occurred in only a quarter
of the
patients in the hypothermia group compared with more than a third
of patients in the control group.
PD - L1 expression intensity was scored on a scale
of 0 to 3 — with» 0» signifying no expression,» 1» signifying weak expression,» 2» moderate, and» 3» strong — and then compared the score with survival data and
outcomes from those
patients.
Colin Collins and Alexander Wyatt, and other researchers
from the Vancouver Prostate Centre at the Vancouver Coastal Health Research Institute, matched 25
patients» treatment
outcomes with the RNA sequence
of their prostate cancer tumors.
The researchers analyzed the relationship between time
from onset
of the blockage to treatment and
outcome among these
patients.
By combining two or more
of these
outcomes to create a single category, you can say it helped «A and B» even if it only helped A and not B. For example, although there was no statistically significant effect
from tPA in the NINDS trial on the number
of patients who died, there was a small decrease in disability for those who survived.