Over time these cells split into two populations.
Over time the cells colonize the shape, or the action of the body will break down the polymers.
By breaking the persistent part of the persistent high pairing,
over time cells become more sensitive.
Not exact matches
The good news is, Apple's new maps should get better
over time, both because data is collected automatically (by
cell towers) and through user feedback and input.
One reason is that,
over time, scalding hot beverages may injure
cells that line the throat, setting the stage for rare cancers.
I often deliver Q&A's to
over 10,000 viewers at a
time, all of this done from my
cell phone.
These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize
cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products
over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from
time to
time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).
Rare earth minerals, the 17 elements used in high - tech products such as
cell phones and hybrid vehicles, represent another potential source of growth for Canadians
over time.
Cognitive neuroscientist Dr. Carmen Simon found that when your message stays consistent
over time, people's brains store it in their «place
cells.»
In the
time of all this fighting we've had [
over embryonic stem -
cell research]-- which did slow down this [adult stem -
cell] research — in the last year we've advanced ten years.»
Over several years Bonhoeffer was interrogated numerous
times, and after returning to his
cell he would contemplate what was truth and what was a lie.
2) scientifically death is the result (natural death) of the imperfect reproduction of
cells within our bodies causing organ failure
over time.
I care about the life people like you are attempting to force in to this world, you care about what appeases your god - big difference when you really don't care or consider the child only what your imaginary friend god wants and yet your god cause abortions all the
time... you care about a clump of
cells, not the actual life of the child and that's much worse than me supporting the rights of a woman to have control
over her body, especially if the clump of
cells couldn't survive outside of the host.
If he went to a caveman and the caveman asked where he came from, the answer «You evolved from a single
cell and
over a
time of millions of years and ebcame a multi-celled intelllegent human» would probably not be understandible by him.
Over the last six years the New York
Times regularly ran front - page stories on the latest stem -
cell news, largely to embarrass the Bush administration, and now we rarely see stem -
cell stories on any page.
Dude has 166,279
cell groups, 172,346 deacons and 12,820 full -
time staff (9,543 of which are ordained clergy) The numbers are beyond comprehension: average Sunday worship attendance is 552,364, a figure amassed in 11 services averaging
over 50,000 each.
Yet just such an unlikely resolution may be in hand for one of the most acrimonious conflicts of recent
times: the debate
over human embryonic stem
cells....
Since all living things are made of
cells, evolution merely describes how
cells change
over time.
I find it incredible, that so many have completely accepted the idea that we could get a single
cell from inorganic matter, that the eye could evolve from beginning with a pigmented spot..., not to mention many
times over, with all the different eyes around even in primitive creatures,...
And let's remember that evolution, while it's a theory, is a theory about the beginning and the transformation of life based on things we have observed, namely that
cells change and mutate and that those mutations can produce
cells that are unique and new, and that it would follow that it's possible for molecules to form into single -
celled organisms which mutate and combine into multi-cellular organisms which mutate, adapt, and grow
over time into new forms of life.
Over the weekend, Neva spent a lot of
time smooshing her little puppy body against the double -
cell honeycomb blinds that insulate our glass deck door.
After both corrugated and plastic surfaces were inoculated, the
cell loads of the microorganisms were checked
over time.
Over time, pickled vegetables become softer and softer as their
cell walls break down further because of the acetic acid and salt used in the pickling process.
The change in load
cell output occurring with
time, while under load, and with all environmental conditions and other variables remaining constant; usually measured with Rated Load applied and expressed as a percent of Rated Output
over a specific period of
time.
On the way home he picked up his
cell and playedCory's last message — «Got us a tee
time Sunday
over at Spencer,» Corysays.
I Came home on his birthday of January the 5th 2000, we had been in touch with his foreman and his union president who were terrified to even approaching my husband about taking the
time from His birthday the 5th OF January the day we were flying in From Germany to the 24th of January as the exchange for having him jailed to work out of a
cell over the holidays.
Buffalo - based attorney Steven Cohen told
Time Warner Cable News Reporter Ryan Whalen, who broke the story last week, that Wozniak has turned
over her
cell phone, email and copies of all her hard drives to the Ethics Committee.
We see some
cell death even in the edge of the organoids starting at 10 weeks, which becomes really dramatic
over time.
Axons can measure several hundred
times the diameter of the
cell body, and, in addition to rapid transmission of electric impulses, they also transport molecular materials
over these distances.
Vaz and Baylin say the results suggest that early epigenetic changes triggered by chronic cigarette smoke exposure can build up
over time and make the airway
cells increasingly sensitive to responding to mutations that initiate cancer.
As the B -
cell levels recover
over time, they begin to churn out antibodies again.
In the case of neural
cells, it means that imprinted methylation is dynamically shaping the adult brain
over time and could play a role in aging.
Specifically, they use a technique called lineage tracing to mark stem
cells and follow the fate of their progeny
over time.
To make stem
cells the basis for safe medical treatments, however, the field would need the ability to tightly control stem
cell pluripotency, the ability to become many
cell types, and self - renewal or immortality, the ability to keep dividing and multiplying
over time in constant turnover.
Ding's team took
cells called fibroblasts from the connective tissues of mouse fetuses and bathed them in a cocktail of the four polyarginine - tagged proteins for 12 hours, then they removed the reprogramming proteins for 36 hours, and repeated this cycle four
times over.
She says that the mistakes don't affect the conclusion of the paper and claims to have recreated these
cells over 200
times.
When the T
cells of your immune system are forced to deal
over time with cancer or a chronic infection such as HIV or hepatitis C, they can develop «T
cell exhaustion,» becoming less effective and losing their ability to attack and destroy the invaders of the body.
The idea that tensegrity dictates the shape and organization of living
cells was initially controversial, but as a result of experimental validation in multiple systems, it has gained greater acceptance
over time.
The most attractive feature of the material is that it allows
cells to survive
over long
time periods.
Over time, growing heaps of rogue proteins overwhelm the system and the
cell gets sick and dies — or, at least, that has been the conventional thinking.
They specifically studied the length of telomeres (repeated DNA sequences) on the ends of chromosomes in leukocytes (white blood
cells); the protective caps are believed to be markers of biological aging, because they shrink
over time.
«
Over time, the probability of these
cells acquiring mutations rises.
Before
cell phones, it was easy to mull
over seemingly random ideas in our free
time.
In people with severe eye disease, transplants made from embryonic stem
cells (in region of black dotted circle) appear safe, and became larger and more pigmented
over time (right).
Researchers also need to test a large number of battery
cells over a long enough period of
time under various physical conditions and temperatures to ensure that dendrites will never grow.
As it can take weeks to grow human
cells into intact differentiated and functional tissues within Organ Chips, such as those that mimic the lung and intestine, and researchers seek to understand how drugs, toxins or other perturbations alter tissue structure and function, the team at the Wyss Institute for Biologically Inspired Engineering led by Donald Ingber has been searching for ways to non-invasively monitor the health and maturity of
cells cultured within these microfluidic devices
over extended
times.
Measuring fluctuations
over time, researchers found that the membrane stiffens as red blood
cells age, impeding
cell operation.
To answer this question, Murphy tracked which genes were turned on and off
over time in the oocytes and somatic
cells in C. elegans IGF - 1 and TGF - β mutants, as well as wild - type worms.
Immunotherapy caused an increase in peanut - specific T
cells, accompanied by a change in the distribution of T -
cell subtypes
over time.
In order to isolate the 3D structure of the chromosome during metaphase, the authors used a combination of chromosome conformation capture technologies (3C, 5C and Hi - C) developed by the Dekker lab
over the last decade to map the points of contact along the mitotic chromosome in different
cell types synchronized to divide at the same
time.