(C) Confocal image of
P150 dystrophic inner retina transplanted with hNPCctx — GDNF and double stained with antibodies against nestin, a neural stem and progenitor cell marker (green) and human nuclear antigen (red).
(E)
P150 dystrophic retina transplanted with hNPCctx — GDNF and stained with cone arrestin antibody showing morphology of rescued cone photoreceptors (arrows point to cone pedicles).
Confocal images of
P150 dystrophic retina transplanted with hNPCctx — GDNF and double stained with antibodies against human nuclear antigen (red) and either (A) recoverin, a photoreceptor and cone bipolar cell marker (green), or (B) protein kinase Cα (PKCα), a bipolar cell marker (green).
Not exact matches
Distant from the subretinal grafts, the ONL was reduced to a single layer at P100 and discontinuous, scattered cells at
P150 (Figure 5G), similar to untreated and sham - treated
dystrophic retinas.