Sentences with phrase «pet tracer»

Objectives: This study tested the efficacy of gallium -68-labeled DOTATATE -LRB-(68) Ga - DOTATATE), a somatostatin receptor subtype - 2 (SST2)- binding PET tracer, for imaging atherosclerotic inflammation.

Title: A PET tracer for brain a2C - adrenoceptors, [11C] ORM - 13070: radiosynthesis and preclinical evaluation in rats and knock - out mice Author: E. Arponen et al..

† This is obviously a critical tool for future research: the Michael J. Fox Foundation has recently stepped up with a $ 2 million prize for the first researcher to create a PET tracer for visualizing AS aggregates in the brain).

Title: Validation of 11C - ORM - 13070 as a PET tracer for a2C - adrenoceptors in the human brain Author: J. Lehto et al..

The DOTA conjugates and some of their corresponding metal complexes retained good CXCR4 affinity, and one 68Ga - labeled compound (35) was further studied as a PET tracer.

«First human application of novel PET tracer for prostate cancer: New tracer holds promise of monitoring targeted treatment of various cancers.»

In the featured translational article in the August issue of The Journal of Nuclear Medicine, researchers at the University of Michigan demonstrate the potential of a new PET tracer, Carbon - 11 labeled sarcosine (11C - sarcosine), for imaging prostate cancer, and set the stage for its possible use in monitoring other cancers.

The researchers designed and synthesized a novel small molecule PET tracer, 18F - MPG, with high specificity to activating EGFR mutant kinase.

Brennica Marlow passed her Qualifying Exam defending her proposal «Cholesterol at the Protein Interface: A look at TSPO and PET tracers»

Not exact matches

Like a key fitting into a lock, the carrier molecules bind to certain receptors or biomarkers and the radioactive atoms enable PET or SPECT scanners to image areas where the tracers have collected in large numbers.

In the 1980s, positron emission tomography (PET) scans, which detect neural metabolism with radioactive tracers, snapped the first pictures of the brain in midthought.

The first - in - human PET / CT imaging of 75 patients with 18F - MPG was performed to show that this tracer can be used as a companion diagnostic to identify NSCLC patients with EGFR activating mutant tumors (primary tumor or metastatic) with 84.3 % accuracy.

PET scans which use fluorodeoxyglucose (FDG) as a tracer can be used for neuronal loss, and are useful when a reliable short - term prediction of cognitive decline is needed.

Using a combination of scanning techniques (positron emission tomography (PET) and computed tomography (CT)-RRB-, the researchers were able to track the progress of the tracer as it moved around the body.

The researchers now plan to further develop the tracer molecules by labeling them with radioisotopes, used during positron emission tomography (PET).

«These include different types of MRI scans, which use strong magnetic fields and radio waves to produce detailed images of the inside of the brain, and Positron Emission Tomography (PET) scans, which use a small amount of a radioactive drug, or tracer, to test how tissues in the brain are actually functioning.

This is the first study to examine and compare beta - amyloid buildup in the brain using the Amyvid amyloid PET imaging tracer between individuals with PPA and those with Alzheimer's memory dementia, the more common disease that causes memory problems.

By using PET and radioactive tracers, the researchers can show the flow of liquid or gas in the rock.

Fluorine - 18 is a popular tracer for revealing cancers and other biological targets in PET scans.

«Seeing more with PET scans: New chemistry for medical imaging: Surprising new mechanism for attaching chemical tracers discovered.»

Chakravarti further notes that because GBM cells take up methionine much faster than normal glioma cells, positron emission tomography that uses methionine as a tracer (MET - PET) might help map GBM tumors more accurately, allowing more precise surgical removal and radiation - therapy planning.

The study compared the effectiveness of the new tracer with 11C - choline (already widely used for imaging prostate cancer) in two mouse models and also performed the first PET / CT scan with 11C - sarcosine of a human with prostate cancer.

Participants in all three groups received a harmless radioactive tracer that illuminates CB1 receptors when exposed to positron emissions tomography (PET scans).

The chosen tracer has a short half - life, so the exposure to radiation is no greater than what is now used in the many PET scans used to detect cancer.

PET scanning, or positron emission tomography, is used to detect minute quantities of tracers, commonly for finding cancer and metastases.

Baseline PET scan shows uptake of manganese chloride tracer in mouse pancreas, in research at the University of Wisconsin — Madison department of radiology.

The chemical reactions she has developed are widely used throughout the pharmaceutical industry to create new drug candidates, are being studied by chemical companies interested in accessing important chemicals used in farming, and are being utilized to prepare a type of chemical (tracer) that allows doctors to view the heart's sympathetic nervous system through positron emission tomography (PET) scans.

We will consider near - infrared, confocal endomicroscopy (two - colour CellVizio technology), two - photon microscopy, single photon emission tomography (SPECT) and positron emission tomography (PET) scan platforms available from CEA, HZI and INRA, and will develop new tracers to tag antigens, adjuvants, particles / vehicles and vectors for the in vivo visualisation of dissemination and biodistribution.

To see how the two gene versions affect the living human brain, the NIMH researchers scanned 24 healthy young adults twice using PET (positron emission tomography), which uses radioactive tracers to visualize brain function.

261 Peter Schlosser, Gerhard Bönisch, Monika Rhein, Reinhold Bayer, «Reduction of deepwater formation in the Greenland Sea during the 1980s: Evidence from tracer data,» Science 251:1054 - 1056 (1 March 1991).

Gerhard Bönisch, Johan Blindheim, John L. Bullister, Peter Schlosser, and Douglas W. R. Wallace, «Long term trends of temperature, salinity, density, and transient tracers in the Central Greenland Sea,» Journal of Geophysical Research 102:18553 - 18571 (1997), see http://www.ldeo.columbia.edu/~noblegas/gerhard/GIN/tspgs/tsp65.html.