Sentences with phrase «pmk kidney cells»

The researchers detected this SMN long noncoding RNA, or lnc - RNA (pronounced «link RNA») for short, in human embryonic kidney cells, brain cell samples and neurons derived from the stem cells of healthy people and those with spinal muscular atrophy type I and II.
Dunsby and colleagues used it to measure glucose uptake, indicated by a fluorescent biosensor, in multicellular kidney cell spheroids.
Fussenegger created his biological calculator by engineering an embryonic kidney cell to respond to two different chemicals: erythromycin (an antibiotic) and phloretin (a compound found in apple trees).
Through the ureter, they fed kidney cells from newborn rats, re-coating the labyrinthine tubules and ducts that make up the kidney's urine filtration system.
In addition, monkeys» kidney cells do not normally support the growth of HIV.
Both vaccines were based on live, weakened strains of polio virus grown in monkeys» kidney cells.
The scientists in London got the same result in a similar experiment using mammalian kidney cells, showing that healthy and mutant cells compete directly against each other in mammals.
«Hydroxyethyl starch has direct harmful effects on kidney cells, lab study finds.»
The authors report that when the inactive halves of DAM attached to Notch and its partners rejoined, they reactivated and allowed the marking of the bound DNA in kidney cells.
The new study suggests that the molecular mass of HES is the major factor responsible for damage to kidney cells.
The researchers inserted the genes for the 25 subtypes into human kidney cells (an easier feat than working with real taste cells).
From left: A kidney scaffold awaits the addition of kidney cells.
Normal human colon cells, kidney cells, lung cancer cells and two strains of colon cancer cells didn't respond to the bacteria.
In previous studies, researchers have successfully differentiated stem cells into heart, liver, pancreas or nerve cells by adding certain chemicals, but kidney cells have proved challenging.
The very next week, Atala isolated the kidney cells he needed, then seeded them onto a decellularized scaffold.
An ear scaffold, left, provides the structure to grow human cells.A kidney stripped of cells, right, awaits an injection of human kidney cells, part of the process of engineering a new organ.
Liver cells and kidney cells are genetically identical apart from their epigenetic marks.
Obesity suppresses an important cellular process that prevents kidney cell damage, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).
«The cryopreservant mixture must be able to get into the kidney cells, and must be gentle towards them,» Fahy says.
Martin Fussenegger and colleagues at the Swiss Federal Institute of Technology in Zurich created biological versions of two key digital circuits inside two sets of embryonic kidney cells: a half adder and half subtractor.
This binding causes kidney cells to change their structure and function, permitting disease onset.
They found that reducing the level of VEGF - A in mouse kidney cells caused kidney failure very similar to that seen in women suffering from preeclampsia.
They found that the mutated G1 and G2 variant did so particularly well on what's known as a receptor on the surface of kidney cells, in this case the suPAR activated receptor alphavbeta3 integrin.
Black people are particularly at risk, given the study's finding that suPAR activates its receptor on kidney cells that then attract the APOL1 risk proteins.
The human kidney cell involved survived the experience, and though we are a long way from the laser eyes of Cyclops from the X-Men franchise, the achievement suggests that «living lasers» might be created inside live animals.
AFRICAN GREEN MONKEY CELL: An African green monkey kidney cell expressing the gene c - src, imaged using Bessel beam plane illumination.
One, FLUCELVAX, is grown in canine kidney cells, and the second, Flublok, is grown in insect cells.)
In observing kidney cells from the FAN1 knockout mice, the researchers noticed that their nuclei were abnormally large.
To find out, the team engineered baby hamster kidney cells to express the human ACE2 receptor.
In those cases, the NPCs often matured into adult kidney cells in a manner of days, leaving no steady population of progenitor cells to study.
Before toying with worms, the S.U.N.Y. Buffalo team tried out their technique on cultures of human embryonic kidney cells and neurons from a rat hippocampus, a part of the brain integral to memory.
Paolo Fiorina, MD, PhD (Boston Children's Hospital / Harvard Medical School) and his colleagues have discovered that a receptor called B7 - 1 is expressed by kidney cells during the progression of diabetic nephropathy.
The Saudi scientists said they had isolated a virus from the patient as well as from one of the camels, grown both samples in monkey kidney cells, and sequenced their genomes, which turned out to be 100 % identical.
«We provide a proof - of - principle for how to make and maintain unlimited numbers of precursor kidney cells,» says Juan Carlos Izpisua Belmonte, professor in Salk's Gene Expression Laboratory.
To upgrade their DNA «switches,» Wong and his colleagues steered clear of transcription factors and instead switched human kidney cell genes on and off using scissorlike enzymes that selectively cut out snippets of DNA.
«Massive single - cell survey of kidney cell types reveals new paths to disease: Study of over 57,000 cells from mouse kidneys help identify human renal disorders.»
These hybrid stretches of DNA were then incorporated into easily - cultured kidney cells.
The study, led by Katalin Susztak, MD, PhD, a professor of Renal - Electrolyte and Hypertension and Genetics, also identified three novel cell populations, along with all previously described kidney cell types.
Reporting in Science, a team led by researchers from the Broad Institute of MIT and Harvard, Brigham and Women's Hospital, and Harvard Medical School describes a new approach to prevent death in these essential kidney cells.
The matrix helps prevent the immune system from rejecting the kidney cells.
In the Nature Communications study, UTSW researchers also reported how miR - 17 causes cyst proliferation: the molecule essentially reprograms the metabolism of kidney cells so that cellular structures called mitochondria use less nutrients, freeing up resources to instead make cell parts that become cysts.
By transferring the gene for melanopsin into human embryonic kidney cells, synthetic biologist Martin Fussenegger of the Swiss Federal Institute of Technology in Zurich and colleagues made these cells light - sensitive as well.
The answer was yes: They found cells with markers from all three major body cell types, called germ layers: ectoderm (such as nerve cells), mesoderm (muscle and blood vessel cells), and endoderm (kidney cells).
An alternative possibility is that successful propagation of TMAdV may depend on infection of a specific host cell type, such as A549 lung, and not BSC - 1 or PMK kidney cells.
COS - 7 African green monkey kidney cells, C2C12 mouse myoblastic cells, MC3T3 - E1 human osteoblastic cells, and U-2 OS human osteosarcoma cells were obtained from ATCC.
The scientists got another surprise when they followed up on this finding with mouse experiments that exposed specialized kidney cells called «podocytes», a key component of the blood filtering, to high levels of glucose.
GOLDENRING, J.R., Aron, L.M., Lapierre, L.A., Navarre, J. and Casanova, J.E. Expression and properties of Rab25 in polarized Madin - Darby canine kidney cells.
Using postmortem kidneys donated from generous Medalists, the Joslin team looked at the levels of thousands of proteins expressed in kidney cells that help to filter blood, and compared the results for Medalists with and without kidney disease.
Similar uptake but different trafficking and escape routes of reovirus virions and infectious subvirion particles imaged in polarized Madin — Darby canine kidney cells.
A Highlights from MBoC Selection: Similar uptake but different trafficking and escape routes of reovirus virions and infectious subvirion particles imaged in polarized Madin — Darby canine kidney cells.
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