Not exact matches
They found that patients whose
tumors tested
positive for ER and
PR, but negative for HER2, were less likely to see their cancer come back.
Since estrogen receptor (ER) and progesterone receptor (
PR) data were available and HER2 status was not, the researchers categorized the
tumors as ER or
PR positive (HR
positive), or both ER and
PR negative (HR negative).
The sesame seed lignan sesamin has been found to reduce breast
tumor area in rats with hormone receptor
positive (ER + /
PR +)
tumors.
After embedding ER
positive /
PR positive breast
tumors in a number of mice, they exposed some of the mice to estrogen only, others to both estrogen and progesterone, and others to no hormones at all.
These associations were primarily limited to hormone receptor —
positive tumors as migraine was associated with a 0.65-fold (95 % CI, 0.51 - 0.83) reduced risk of estrogen receptor —
positive (ER +) / progesterone receptor —
positive (
PR +) ductal carcinoma.