June 15, 1:00 p.m. EDT: How to Talk to
Your Patients About a Clinical Trial, with Lise Hernandez, RN, MPH, clinical research coordinator at Roswell Park Cancer Institute.
Not exact matches
We do this by conducting
clinical trials in which we collect safety and efficacy data
about our experimental drugs with the goal of submitting those data to regulatory authorities, like the U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMA), so that these experimental drugs can be approved for use by
patients.
With A3AR drugs demonstrating good safety profiles in
clinical trials as anti-inflammatory and anti-cancer agents, Salvemini and colleagues are enthusiastic
about the potential of these new drugs to treat chronic pain in
patients.
Her work has many components: helping community cancer advocacy organizations write research grants, educating community organizations
about cancer research, and matching
patients from minority communities with
clinical trials.
Similarly,
patients who chose not to enroll in a
clinical trial cited concerns
about insurance not covering costs, and fear that their out - of - pocket costs would increase.
«They want to trust that the doctor is doing only things that would improve their health,» Weinfurt says
about patients who might enroll in a
clinical trial.
The optical prosthetics, tiny enough to be balanced on a fingertip, dramatically improved the vision of
about two thirds of the 206
patients studied in a 24 - month
clinical trial, according to a new study published in Archives of Ophthalmology.
Medical researchers are talking
about starting an online archive where they could post unreviewed results from
clinical trials, such as one that tested this light therapy for cancer
patients.
«Most
patients simply do not know
about clinical trials that could help them,» observes Robert Comis, president of theCoalition of National Cancer Cooperative Groups, which conducts
clinical trials for the National Cancer Institute.
An investigation into how
patient outcomes are assessed in
clinical trials has revealed a worrying lack of consistency, raising concerns
about funding being wasted on the acquisition of poor quality data.
When
patients sign up for
clinical trials to test an experimental drug, procedure or device, they give their informed consent after doctors counsel them
about the risks and uncertainty associated with a not - yet - approved intervention.
«Currently,
about 80 percent of
patients in these
clinical trials provide no useful information,» says Dr. Krolewski.
In collaboration with the University College London (UCL) Cancer
Trials Centre and the UCL Cancer Institute, Swanton's research group will be following
about 850
patients with NSCLC from diagnosis to death as part of a
clinical trial to understand tumor evolution.
Researchers running
clinical trials planned to stop enrolling new
patients, and furloughs were scheduled for all but
about a quarter of NIH's 19,000 staff members, who were deemed «essential» to care for
patients and maintain animals and cell lines.
Today, just
about three percent of cancer
patients participate in
clinical trials.
«This is what we have dreamed
about: drugs that can be targeted to a
patient's specific tumor, to the mechanism that caused the cancer,» says Alice Shaw, Martensen's oncologist and a chief investigator in the Xalkori
clinical trial at Mass General.
The key achievement of activists has been to get
clinical researchers and their
patients talking to each other
about what they want out of
clinical trials for new drugs.
March 16, 2006
Clinical trial measures ability of focused heat treatment to reduce asthma symptoms The University of Chicago Hospitals is one of about 30 centers around the world, and the only one in Illinois, participating in the Asthma Interventional Research 2 (AIR2) clinical trial, the first U.S. trial of «Bronchial Thermoplasty,» an experimental treatment for patients with moderate to severe
Clinical trial measures ability of focused heat treatment to reduce asthma symptoms The University of Chicago Hospitals is one of
about 30 centers around the world, and the only one in Illinois, participating in the Asthma Interventional Research 2 (AIR2)
clinical trial, the first U.S. trial of «Bronchial Thermoplasty,» an experimental treatment for patients with moderate to severe
clinical trial, the first U.S.
trial of «Bronchial Thermoplasty,» an experimental treatment for
patients with moderate to severe asthma.
Georgia CORE aims to increase the skills and competencies of the cancer research workforce; raise awareness
about the opportunities and benefits of
clinical trials; incorporate the perspectives of
patients and survivors into
clinical cancer research; advocate for
clinical trials financing, regulatory improvement and resource development; promote access to and enrollment in
clinical trials; and stimulate dialogue and collaboration among multi-disciplinary cancer researchers.
For more information
about cancer
clinical trials at Vanderbilt - Ingram Cancer Center:
Patients
This could improve
patient risk - stratification for
clinical trials, aid
clinical decision - making, and improve
patient / doctor communication
about prognosis and treatment planning, Dr. Roncolato said.
Sharma spoke
about one example of this approach: a recently launched CRI
Clinical Accelerator
trial testing a CD40 - based immunotherapy in combination with checkpoint immunotherapy and chemotherapy for
patients with pancreatic cancer.
Concerns
about immunological consequences of rAAV - mediated gene transfer were substantiated by the outcome of a
clinical trial in which human hemophilia B
patients were infused into the liver with rAAV -2-F.
«We have been very concerned
about reports of
patients using unproven medical therapies whose safety and efficacy have not been tested in systematic
clinical trials,» he said.
«We have a larger number of
patients in our group than on any single
clinical trial, so we hope this will be an opportunity for researchers to learn
about us and a way for us to learn more
about our condition.
«The surge in cancer immunotherapy research and
clinical trials has resulted in an unprecedented flood of data
about patient responses to immune - based treatment, and we believe these data hold the key to unlocking the full potential of this treatment modality for more and eventually all cancer
patients,» said Jill O'Donnell - Tormey, Ph.D., CEO and director of scientific affairs at the Cancer Research Institute.
NIH studies on the issue cite a number of different reasons that
patients elect not to participate in
clinical trials, including fear of a reduced quality of life, concern
about receiving a placebo, potential side effects, and concern that the experimental drug might not be the best option.
Lysogene's MPS IIIA gene therapy
clinical trial strategy includes a partnership with the MPS
patient networks to ensure families are well informed
about our development program and are able to make informed choices concerning the best treatment strategy for their children.
Loyola's
patients benefit from our research discoveries; read
about Loyola's current
clinical trials.
Clinical trials are an important part of my practice, and I often engage in discussions with my
patients about participating in an appropriate therapy.
There were multi-disciplinary and international video - conference discussions
about the best healthcare pathways for many
patients with severe tracheal injuries in 2012, which included
patients later operated on as part of the
clinical trial based in Russia.
We're very excited
about bringing this new series of
clinical trials to our
patients.
Yet another study, a meta - analysis of seven
clinical trials involving
about 1,150
patients with bleeding ulcers, found that higher doses of proton pump inhibitors did not reduce the risk of additional bleeding, need for surgery, or death more effectively than lower doses did.
Claremont, CA, United States
About Blog What started as a personal journey of a doctor turned
patient morphed into a way to share what's universal in dealing with cancer, in my case a nasty leukemia (CLL), a failed transplant and a successful
clinical trial.
Read
about clinical activities at the veterinary hospital, including our latest procedures, stories
about inspiring
patients and their families, spotlights on hospital faculty and staff, and our latest
clinical trials.
Claremont, CA, United States
About Blog What started as a personal journey of a doctor turned
patient morphed into a way to share what's universal in dealing with cancer, in my case a nasty leukemia (CLL), a failed transplant and a successful
clinical trial.
Claremont, CA, United States
About Blog What started as a personal journey of a doctor turned
patient morphed into a way to share what's universal in dealing with cancer, in my case a nasty leukemia (CLL), a failed transplant and a successful
clinical trial.
Another meta - analysis reached similar conclusions
about the equivalence of CBT and BT1 and a recent large - scale
clinical trial of BT showed that it was as effective as antidepressant medication for depression.3 While BT and CBT were equally as effective for lower - levels of depression severity,
patients with severe depression specifically benefited more from BT than CBT.3 Behavioural activation, which involves graded activity and goal scheduling, is the central component of BT for depression and may be related to a more general mechanism of change that is operating in many different treatments for depression, especially CBT.
Claremont, CA, United States
About Blog What started as a personal journey of a doctor turned
patient morphed into a way to share what's universal in dealing with cancer, in my case a nasty leukemia (CLL), a failed transplant and a successful
clinical trial.