Not exact matches
The idea to specifically study this group of patients was based on groundbreaking research Garon published in the
New England Journal of Medicine last year, which found that among patients who received
pembrolizumab, those with PD - L1 expression on at least 50 percent of their cancer cells showed the longest survival and disease control.
Pembrolizumab and nivolumab, for example, the
newest inhibitors to win FDA approval, target a checkpoint called PD - 1, through which tumors can induce a T cell to deactivate.
Pembrolizumab is set to become a
new option for first line treatment of patients with advanced lung cancer and high PD - L1 expression, according to the results of the phase III KEYNOTE - 024 trial presented at the ESMO 2016 Congress in Copenhagen and published in the New England Journal of Medici
new option for first line treatment of patients with advanced lung cancer and high PD - L1 expression, according to the results of the phase III KEYNOTE - 024 trial presented at the ESMO 2016 Congress in Copenhagen and published in the
New England Journal of Medici
New England Journal of Medicine.
These results support the use of
pembrolizumab as the
new standard of care for advanced bladder cancer,» concluded Dr Necchi.
Clinical trials of a
new immunotherapy,
pembrolizumab, have shown that it prolongs life significantly for patients with bladder cancer and is active against a rare sub-type of melanoma, called mucosal melanoma.
One patient was treated with the immunotherapy
pembrolizumab and now more than a year after starting treatment remains on the drug with 77 percent tumor reduction and no
new metastases.
Pembrolizumab, an antibody drug already used to treat other forms of cancer, can be effective in the treatment of the most common form of mesothelioma, according to a
new study led by investigators from the Perelman School of Medicine at the University of Pennsylvania.
Rizvi called
pembrolizumab a «promising
new approach» for the treatment of non-small cell lung cancer.
The combination of the attenuated oncolytic virus talimogene laherparepvec (T - VEC) and the immune checkpoint inhibitor
pembrolizumab shows activity and is well tolerated by advanced melanoma patients, according to a
new study presented at the Society for Melanoma Research 2015 International Congress, held November 18 — 21 in San Francisco.