Persisting high insulin sensitivity among middle - aged and older individuals in non-westernized traditional populations at a time when they still maintained their ancestral lifestyle, such as the African pygmies, the Ainu people of Japan, rural communities in Papua New Guinea, and traditional Pacific Islanders.
Among a cohort of adolescent migraineurs with obesity who participated in a weight loss program, compared to those who had remission of migraines, those whose migraines
persisted had
higher waist circumference, body mass index, triglycerides, and HOMA - IR, all of which indicate worse
insulin sensitivity (11).