Disproportionately high
plasma insulin concentration in hypertensive patients was first reported in the scientific literature more than fifty years ago.
Relation of Habitual Diet to Fasting
Plasma Insulin Concentration and the Insulin Response to Oral Glucose, Human Nutrition Clinical Nutrition.
«A High Fasting
Plasma Insulin Concentration Predicts Type 2 Diabetes Independent of Insulin Resistance: Evidence for a Pathogenic Role of Relative Hyperinsulinemia,» Diabetes, 49 (12), 2094 - 2101.
In a chronic sleep deprivation experiment, young mice were sensitized to insulin and had improved control of their blood sugar, whereas aged animals became hyperglycemic and failed to maintain appropriate
plasma insulin concentrations.
Moreover, the same Kitavans had lower fasting
plasma insulin concentrations (2 - 6 IU / mL) compared to healthy Swedes (4 - 11 IU / mL).
Mean 24 - h
plasma insulin concentrations in 19 healthy subjects during visits 1 (□), 2 (•), and 3 (▵) to the General Clinical Research Center.
Plasma insulin concentrations were measured by using a radioimmunoassay (Abbott SpA, Latina, Italy).
Fasting plasma glucose and insulin concentrations were reduced to control concentrations, and
plasma insulin concentrations during the OGTT were significantly lower than those in the the rats fed fructose only at all time - points.
Daily plasma glucose concentrations were 10 percent lower with the high - fiber diet than with the ADA diet (values for the area under the curve, 3743 ± 944 vs. 3365 ± 1003 mg ․ hour per deciliter [207.8 ± 52.4 vs. 186.8 ± 55.7 mmol ․ hour per liter]; P = 0.02), and
plasma insulin concentrations were 12 percent lower (values for the area under the curve, 1107 ± 650 vs. 971 ± 491 μU ․ hour per milliliter [6642 ± 3900 vs. 5826 ± 2946 pmol ․ hour per liter]; P = 0.05)(Figure 1).
Not exact matches
Liposuction did not significantly alter the
insulin sensitivity of muscle, liver, or adipose tissue (assessed by the stimulation of glucose disposal, the suppression of glucose production, and the suppression of lipolysis, respectively); did not significantly alter
plasma concentrations of C - reactive protein, interleukin - 6, tumor necrosis factor alpha, and adiponectin; and did not significantly affect other risk factors for coronary heart disease (blood pressure and
plasma glucose,
insulin, and lipid
concentrations) in either group.
Furthermore, homozygosity for null mutations at CYP2F1 was found associated with higher
plasma interleukin - 8
concentrations; and at either A3GALT2 or NRG4, with markedly reduced
plasma insulin C - peptide
concentrations; hence identifying novel phenotypic associations at these genes.
Common genetic variants at the ARL15 locus are associated with
plasma adiponectin,
insulin and HDL cholesterol
concentrations, obesity, and coronary atherosclerosis.
The meal - related changes in
plasma insulin and glucose
concentrations were as expected, as shown in Figure 5 and Figure 6, respectively.
Values for the 24 - h integrated area under the curve (AUC) of
plasma leptin,
insulin, and glucose
concentrations versus time were calculated above zero
concentration by using the trapezoidal rule.
Effect of twenty - four hours of starvation on
plasma glucose and
insulin concentrations in people with untreated non-
insulin-dependent diabetes mellitus
Plasma insulin, leptin, and ghrelin
concentrations were measured frequently over 24 - h periods to elucidate the mechanism of any observed changes in appetite or body composition.
Blood was sampled frequently at the end of each diet phase to measure the area under the
plasma concentration versus time curve (AUC) for
insulin, leptin, and ghrelin.
No significant differences were observed in fasting
plasma concentrations of free fatty acids, glucose, or
insulin measured during visit CRC1, CRC2, or CRC3 (Table 6).
The
insulin - independent oxidative upregulation of
insulin receptor signaling activity (basic IRS) results in inhibition of autophagic removal of damaged cell structures (Autophagy) and ability to maintain post-absorptive
plasma cysteine
concentrations.
The scientists found that there were no differences in «
plasma glucose, free fatty acids, ketone bodies,
insulin, and epinephrine
concentrations» between fasting and non-fasting conditions.
The researchers found that there were no differences in «
plasma glucose, free fatty acids, ketone bodies,
insulin, and epinephrine
concentrations» between fasting and non-fasting conditions (30)
Patients with advanced AD show higher
plasma but lower CSF
insulin concentrations than healthy controls.40 Clearly, then, the lower
concentration of
insulin in the brain is not a result of reduced circulating levels in the blood.
Since fasting
plasma glucose
concentration depends entirely on the fasting rate of liver glucose production, that dropped also after one week because the liver was now becoming responsive to
insulin.
Dietary Correlates of
Plasma Insulin - like Growth Factor 1 and
Insulin - like Binding Protein 3
Concentrations.
You need to have a high
plasma glucose
concentration and spiked serum
insulin levels to drive maximum cellular creatine delivery.
When Sprague - Dawley rats were fed a diet including 148 mg green tea catechins / d for 12 d, fasting
plasma glucose and
insulin concentrations and the
insulin response to an oral glucose load (2 g glucose / kg body wt) were significantly reduced (9).
Diets high in protein or saturated fat do not affect
insulin sensitivity or
plasma concentrations of lipids and lipoproteins in overweight and obese adults.
The high - fiber diet also lowered the area under the curve for 24 - hour
plasma glucose and
insulin concentrations, which were measured every two hours, by 10 percent (P = 0.02) and 12 percent (P = 0.05), respectively.
Mean (± SE) 24 - Hour Profile of
Plasma Glucose
Concentrations (Panel A) and
Insulin Concentrations (Panel B) during the Last Day of the American Diabetes Association (ADA) Diet and the Last Day of the High - Fiber Diet in 13 Patients with Type 2 Diabetes Mellitus.
Lactate, which increases during starvation, can induce hepatic ketogenesis.2 Low - carbohydrate, fat - rich meals can enhance alpha - cell secretion of glucagon and lower
insulin concentrations.3, 4
Plasma fatty acid
concentrations can be twice as high during low - carbohydrate diets as compared with the usual carbohydrate intake in the postabsorptive period.5 Increased
concentrations of free fatty acids in the absence of carbohydrate - induced inhibition of beta - oxidation of fatty acids and in the presence of an abnormally high ratio of glucagon to
insulin and elevated
concentrations of lactate may have caused ketoacidosis in our patient, who was trying to avoid all dietary carbohydrates.
Both the oat bran and wheat farina with oat gum meals reduced the postprandial rise in
plasma glucose and
insulin concentrations compared to the wheat farina meal without the oat gum.
Short - term zinc supplementation in women with non-
insulin-dependent diabetes mellitus: effects on
plasma 5» - nucleotidase activities,
insulin - like growth factor I
concentrations, and lipoprotein oxidation rates in vitro.
Relationships between
plasma insulin - like growth factor - 1 and
insulin concentrations in multiparous dairy cows with cytological endometritis