Sentences with phrase «postchallenge hyperinsulinemia»

Hyperinsulinemia is associated with hypertension, obesity, dyslipidemia, and glucose intolerance (collectively known as metabolic syndrome).

Women with PCOS and hyperinsulinemia typically have higher levels of testosterone and suffer from mild acne to increased hair on their face, neck and abdomen.

Prenatal Testosterone Exposure Leads to Gonadal Hormone - Dependent Hyperinsulinemia and Gonadal Hormone - Independent Glucose Intolerance in Adult Male Rat Offspring.

This is in agreement with the situation in vivo, where defects in GS activity are compensated for by hyperinsulinemia and hyperglycemia until glycogen synthesis becomes «normal.»

Background: WNIN / Gr - Ob rats demonstrate features of metabolic syndrome that include obesity, insulin resistance, impaired glucose tolerance, and hyperinsulinemia.

Accelerated weight gain on HFD, incident hepatic steatosis, and hyperinsulinemia of XX animals mainly depended on the amount the X chromosomes.

It is unclear whether this defect is primary or acquired secondary to dyslipidemia, hyperinsulinemia, or hyperglycemia.

Testosterone deficiency aggravates the MetS in men by bringing forward obesity and hyperinsulinemia, which in turn suppresses testicular androgen production («vicious cycle»)(also discussed in II.G).

Furthermore, these variables could be secondarily modified by chronic hyperinsulinemia.

Our dose - response curve at chronic high insulin levels allowed us to differentiate between a primary defect (probably genetic) and the induction of secondary insulin resistance in myotube cultures due to hyperinsulinemia.

They either activate or inactivate cellular receptors, cell responses, and other targets and can cause higher insulin resistance and hyperinsulinemia.

To study the effects of hyperinsulinemia on atherosclerosis, Rask - Madsen and his colleagues created mice with fewer insulin receptors in every tissue of the body and compared them to mice with intact insulin receptors.

We propose that in this animal model the age - associated decrease in hepatic (rather than peripheral) insulin action is the major determinant of fasting hyperinsulinemia and that increased visceral adiposity plays the major role in inducing hepatic insulin resistance.

Scientists have known for some time that insulin resistance and hyperinsulinemia cause increased lipids in the circulation, which indirectly leads to atherosclerosis.

This model allowed the researchers to study the effects of hyperinsulinemia without the confounding effects of insulin resistance.

However, the Joslin study, published in the May issue of the journal Arteriosclerosis, Thrombosis, and Vascular Biology, shows that, without other factors such as high blood pressure and high cholesterol, hyperinsulinemia alone does not cause atherosclerosis.

In this condition, vascular cells could become dysfunctional because of hyperinsulinemia or because vascular cells themselves are insulin resistant, which is caused by increased insulin production from pancreatic beta cells as a compensatory mechanism to overcome insulin resistance.

WNIN / Gr - Ob rats demonstrate features of metabolic syndrome that include obesity, insulin resistance, impaired glucose tolerance, and hyperinsulinemia.

Hyperinsulinemia in fructose - induced hypertriglyceridemia in the rat.

WNIN Mutant Obese Rats Develop Acute Pancreatitis With the Enhanced Inflammatory Milieu WNIN Mutant Obese Rats Develop Acute Pancreatitis With the Enhanced Inflammatory Milieu WNIN / Gr - Ob rats demonstrate features of metabolic syndrome that include obesity, insulin resistance, impaired glucose tolerance, and hyperinsulinemia.

The results were that the mice were protected against hyperinsulinemia, obesity, hepatis steatosis, various organ inflammations and had their motor coordination increased, despite consuming the same amount of calories in comparison to the control group of mice that were allowed to consume their food whenever they preferred throughout the day.

Over time, hyperinsulinemia can occur, which is where levels of insulin are up for so long that eventually the body's cells become resistant to its effects — leading to insulin resistance.

Hyperinsulinemia stimulates de novo lipogenesis transforming excess dietary carbohydrates into new fat.

Insulin resistance and hyperinsulinemia are extremely common in PCOS, affecting about 64 % of all women with the disorder, mainly those who are overweight or obese (2).

They observed an improvement in hyperinsulinemia and insulin resistance in the berberine group.

That's oxaloacetate (from the Kreb cycle) and neuropeptide Y (a brain chemical) working with your hyperinsulinemia (feel like rocket science yet?).

Obesity, high blood pressure, and the other manifestations of hyperinsulinemia were notably absent.

Despite the limited formal research on low - carb and ketogenic diets in women with PCOS, it stands to reason that any way of eating that decreases insulin resistance and hyperinsulinemia may be effective for managing the disorder.

Finally, Staffan noted and reported an absence of acne in 1,200 Kitavans including 300 aged 15 - 25 years, which is to be expected, since a major cause of acne appears to be insulin resistance combined with hyperinsulinemia.

Since milk stimulates insulin spikes, it would make sense to wonder whether milk increases our risk of obesity and the many other health problems associated with hyperinsulinemia (high insulin levels).

This can ultimately lead to diseases like hyperinsulinemia, hyperglycemia and Diabetes Type II.

«Effect of sustained physiologic hyperinsulinemia and hyperglycemia on insulin secretion and insulin sensitivity in man» Diabetologia Oct1994, Vol37, Iss 10, 1025 - 1035 Del Prato S.

«A High Fasting Plasma Insulin Concentration Predicts Type 2 Diabetes Independent of Insulin Resistance: Evidence for a Pathogenic Role of Relative Hyperinsulinemia,» Diabetes, 49 (12), 2094 - 2101.

The underlying problem is excessive dietary glucose and fructose causing hyperinsulinemia, not lack of exercise.

Maybe you have discussed this elsewhere, but have you seen any data on whether the insulin / cortisol relationship goes both ways, ie does insulin resistance / hyperinsulinemia cause HPA dysfunction?

Well, many with a good (low) insulin response at the start will inevitably drift into hyperinsulinemia over time, given our ridiculous food supply since the 1970's.

However, having too much insulin in the bloodstream (hyperinsulinemia) is strongly linked to CAD (3, 4, 5).

While I can appreciate Mr. Feldman's efforts and I am also a hyper responder, I have no doubt that cholesterol levels are merely an artifact / symptom of the real cause of CVD which is hyperinsulinemia which for type 2 diebetics or pre-diabetics (which are simply undiagnosed diabetics) is due to high carbohydrate diets causing high blood glucose levels as well as other known causes of infllammation such as trans fat and high omega 6 to omega 3 ratios.

Low carbohydrate diets stabilize insulin levels, and therefore I believe that these diets can also be used to successfully manage all kinds of other chronic health problems which are associated with hyperinsulinemia (high insulin levels).

Recent studies have proved that this protein helps to the control of hyperglycemia, hyperlipidemia, hyperinsulinemia and reduced body weight.

But obesity is by definition a disease caused by too much insulin — hyperinsulinemia.

Obesity: Hyperinsulinemia suppresses the action of the luteinizing hormone (LH), which can reduce circulating testosterone levels

Yes, having hyperinsulinemia — too high levels of insulin in the blood — like type 2 diabetics have, is not a good thing, and may increase cancer by like 10 %.

[A] deficit of GnT - 4a glycosyltransferase expression in beta cells... produced signs of metabolic disease, including hyperglycemia, impaired glucose tolerance, hyperinsulinemia, hepatic steatosis and diminished insulin action in muscle and adipose tissues.

Both GRAINBRAIN and MEATHEAD in EXCESS on a chronic basis after every meal when consumption makes hyperinsulinemia this causes Alzheimer's.

A classical ketogenic diet — with a staggering 70 - 90 percent of total calories coming from fat — might not be necessary.51 Classical ketogenic diets restrict protein as well as carbohydrate, since 48 - 58 percent of the amino acids in dietary proteins can be glucogenic, thereby undermining the purpose of a diet intended to generate a high amount of ketones and limit glucose as much as possible.46 As therapy for AD, however, simply lowering carbohydrate intake to a point where some ketones are generated and hyperinsulinemia is corrected could have positive effects just by easing the metabolic burden on the brain.

Hyperinsulinemia is the strongest known risk factor in non-E4 carriers, and overcomes whatever protection their genes might provide.

If subpopulation, lets say, adapted to low CHO, then more CHO might lead to bunch of more or less stealth problems, from indigestion over hyperinsulinemia to microbiota rebalancing (which, now we know, release some neurotransmitters on its own and thus influence not only physical health but behavior apart from their ability to use or create nutrients we need).

The phenomenon of resistance depends not only upon hyperinsulinemia, but also upon the persistence of those elevated levels.

Since type 2 diabetes is a disease of hyperinsulinemia and insulin resistance, the intermittent fasting strategy will succeed where caloric restriction will not.