Previous cancer studies had shown that by injecting tumors with magnetic nanoparticles made of iron oxide — «essentially rust, with well - tuned magnetic properties,» Anikeeva says — then exposing them to rapidly alternating magnetic fields, excited nanoparticles can be used to heat and destroy cancer tumors while leaving surrounding, healthy tissue intact.
Not exact matches
The IMvigor211
study had been meant to confirm a
previous trial, called IMvigor210, that was central to the U.S. Food and Drug Administration's accelerated approval last year of Tecentriq against bladder
cancer.
While
previous studies have also suggested a link between breastfeeding and reduced breast
cancer risk, results have been mixed, Stuebe writes.
«This robust
study clearly reinforces that screening remains an effective option for detecting breast
cancers, and challenges
previous estimates of the number of women who are overdiagnosed as a result of breast screening.
Their analysis of data in
previous studies done by The
Cancer Genome Atlas group have shown that the types of abnormal methylation levels they found are lower in smokers who have quit for more than 10 years than those who have not quit.
Still,
previous studies have associated abdomen fat to higher risks of
cancer, cardiovascular events and death.
Many
studies have shown serum TK1 to be a valuable
cancer biomarker, but most
previous assays have been enzyme - activity based and may underestimate its presence in solid tumors.
Previous studies by the University of South Carolina's Lucia Pirisi - Kim Creek research group had reported the existence of an HPV - inactive class in head and neck
cancers and raised the possibility that HPV - inactive cervical
cancers might originate as virally driven
cancers and subsequently act independent of HPV.
Previous studies have examined
cancer stem cells (CSCs)-- small populations of cells within a tumor that are resistant to chemotherapy.
The trial, a phase 3
study involving major
cancer research institutions in Europe, the United States, Australia and Japan, enrolled 800 patients with metastatic colorectal
cancer that was progressing despite
previous treatment.
Previous studies have implicated the roles of both EDD1 and TIP60 in
cancer progression, however their roles in viral - mediated
cancers have not been well - explored.
Previous studies have found that, in at least half of cases, the
cancer cells become resistant to erlotinib by developing a second mutation.
«
Previous studies had tested the use of rosiglitazone for
cancer treatment, but the outcome was not encouraging.
Previous studies have found that magnesium is inversely associated with the risk of diabetes, which is a risk factor of pancreatic
cancer.
These carriers were found to have only a 56 % chance of developing breast
cancer by age 70, compared with a figure of 87 % in
previous studies.
The researchers found that only 16 % of women with a family history of breast
cancer had BRCA1 mutations, compared with the 45 % found in
previous studies.
While
previous studies have surveyed the genomic characteristics of tumors confined to the prostate gland, the new
study is the first to focus on metastatic hormone resistant prostate
cancers, which can be difficult to treat because they often develop resistance to standard treatments.
Previous studies of genetic alterations in lymphoma and lung
cancer have found that certain genetic mutations — specifically when part of a gene breaks off and gets fused to another — can inappropriately switch on ALK, driving
cancer cells to grow and divide.
Several
previous studies have found an association between increasing nut consumption and a lower risk of diseases such as heart disease, type 2 diabetes, colon
cancer, gallstones, and diverticulitis.
Most
previous studies asked patients already diagnosed with a disease, such as brain
cancer, to recall past cell phone use — a less reliable method.
Previous studies have shown links between human gut bacteria and increased risk of a wide variety of diseases including diabetes, autism, heart disease, and even some forms of
cancer.
The
study builds on
previous findings suggesting that AIM2 limits
cancer cell growth in colon
cancer cell lines, Wilson said, as well as on a clinical report of poor prognosis in colon
cancer patients with low or missing AIM2 levels.
But he notes that NSAIDS taken by migraine patients may account for the lower
cancer risk as
previous studies have shown.
Previous studies have indicated that cervical
cancer survivors treated with radiation have an increased risk for second primary malignancies, yet no preventive recommendations have been established.
«We know from
previous research that lack of insurance typically results in diagnosis of
cancer at a later, and usually less treatable, stage,» said lead study author Xuesong Han, PhD, Strategic Director, Health Policy and Healthcare Delivery Research, American Cancer So
cancer at a later, and usually less treatable, stage,» said lead
study author Xuesong Han, PhD, Strategic Director, Health Policy and Healthcare Delivery Research, American
Cancer So
Cancer Society.
What's more, the researchers found that blocking this mechanism with HCQ — a drug used to treat malaria that has been shown in
previous studies to block autophagy — limited BRAF inhibitor - induced autophagy and enhanced
cancer cell death in mouse models.
Semenza says
previous studies have shown that resistance to chemotherapy arises from the hardy nature of
cancer stem cells, which are often found in the centers of tumors, where oxygen levels are quite low.
«This miRNA suppresses expression of HMGA1, a gene that was shown in
previous studies to be associated with prostate
cancer progression and recurrence,» says Leung.
Previous studies had linked high genetic diversity within bacterial infections or in
cancers with poor outcomes for patients treated with antimicrobial or chemotherapy drugs.
Previous studies suggest the drink may protect against
cancer of the prostate or lung.
Previous studies, he adds, have shown that taking testosterone at the wrong time — particularly by men with symptoms of active
cancer progression who have not yet received testosterone - blocking therapy — can make the disease worse.
He adds that although the new research from Japan found no link between tea consumption and
cancer risk, more research is needed to resolve the conflict between this and
previous cancer - related
studies.
Dr Kirstin De Bruijn will tell the 2013 European
Cancer Congress (ECC2013) that previous studies have examined the association between diabetes and dying from cancer but death from specific types of cancer has not been well - st
Cancer Congress (ECC2013) that
previous studies have examined the association between diabetes and dying from
cancer but death from specific types of cancer has not been well - st
cancer but death from specific types of
cancer has not been well - st
cancer has not been well -
studied.
«
Previous studies have linked increased stress with accelerated onset of metastasis in some forms of breast
cancer,» said Michelle L. Halls, Ph.D., a researcher involved in the work from the Drug Discovery Biology Theme at Monash Institute of Pharmaceutical Sciences at Monash University in Parkville, Victoria, Australia.
The tolerability profile in patients with advanced
cancer was similar to that observed in two
previous studies in 150 healthy volunteers who received entolimod in a similar dose range.
For the animal
study, the researchers separated 52 mice with colon
cancer tumors into three groups, including a control group and groups that were fed either the grape compounds or sulindac, an anti-inflammatory drug, which was chosen because a
previous study showed it significantly reduced the number of tumors in humans.
Previous studies have indicated that non-Hispanic blacks and Hispanics were more likely to be diagnosed with triple negative breast
cancer than non-Hispanic whites.
Previous studies have shown that a small molecule known as ONC201 currently in advanced
cancer clinical trials, targets self - renewing colorectal
cancer stem cells.
Previous studies have suggested that eating lots of red and processed meat increases the risk of colorectal
cancer and it is estimated that around 1 in 5 bowel
cancers in the UK are linked to eating these meats.
Previous studies have hinted that silver compounds could also kill
cancer cells.
Because there is a known clinical connection between eye melanoma and skin
cancer, in this
study researchers sought to determine whether there were commonly shared genetic factors between both diseases, as the inherited genetic risk of skin melanoma has been more extensively explored in
previous medical literature.
Previous studies from these researchers have showed that FL118 induces
cancer cell death, or apoptosis, by inhibiting expression of multiple cell - survival proteins (survivin, Mcl - 1, XIAP or cIAP2).
Previous research looked at high doses of purified resveratrol to
study its potential to prevent
cancer.
«Most
previous studies aggregate all comorbidities into an index with little consideration of how a specific comorbid condition can impact lung
cancer outcomes in an individual,» Islam said.
Study findings were consistent with
previous research suggesting that elderly women are at high - risk for inadequate surgical treatment of
cancer.
The ARIC data were especially useful to
study because unlike most
previous research linking gum disease and
cancer risk, periodontitis cases were determined from dental examinations performed as part of the ARIC
study rather than participants» self - reports of the disease.
Previous studies had suggested that a gene mutation known as W4P / R was associated with higher incidence of liver
cancer and cirrhosis.
In
previous studies, including recent genome sequencing of
cancer patients, human SETD2 has been implicated in several
cancer types, especially in renal cell carcinoma — the most common kind of kidney
cancer.
Previous studies have suggested that shorter telomeres are linked to heart disease, dementia and
cancer.
While this
study suggests that survivors often report strong social connections, our
previous studies have reported that childhood
cancer survivors are more likely than their peers to struggle mentally and physically and report issues like distress and loneliness,» Huang said.