Within a few months of his diagnosis of
primary cutaneous T - cell lymphoma, he developed systemic involvement of T - cell lymphoma in an axillary lymph node, bone marrow and lung.
We describe a 66 - year - old man with a long - standing history of squamous cell carcinoma of the head and neck region who developed nodular - sclerosing subtype of classical Hodgkin lymphoma and
primary cutaneous CD8 - positive, cytotoxic variant of mycosis fungoides over a 1 - year period of time.
According to the FDA, cobimetinib may cause severe side effects including cardiomyopathy or rhabdomyolysis,
primary cutaneous malignancies, retinal detachment, hepatotoxicity, hemorrhage, and severe skin rash due to increased sensitivity to sunlight.
Brentuximab vedotin was previously approved by the FDA to treat cHL after relapse, cHL after stem cell transplant when a patient is at a high risk of relapse or progression, systemic anaplastic large cell lymphoma (ALCL) after failure of other treatment, and
primary cutaneous ALCL after failure of other treatment.
Ebstein - Barr Virus - Negative Clonal Plasma Cell Proliferations Associated With Systemic Involvement of
Primary Cutaneous T - Cell Lymphoma
We conducted bioinformatic analyses of 703 transcriptomes to probe the immune landscape of
primary cutaneous melanomas in a population - ascertained cohort.
Thin stage
I primary cutaneous malignant melanoma.
Not exact matches
The dermis contains copious numbers of
cutaneous dendritic cells that are important for an intradermal route of immunization.10 Dendritic cells are the most potent antigen - presenting cells for eliciting
primary immune responses.
Older men are more likely to be diagnosed with multiple
primary melanomas and have worse
cutaneous malignant melanoma — specific survival than men with a single
primary melanoma.
ONC201 demonstrated (GI50 1 - 8 µM) dose - and time - dependent efficacy in acute myeloid leukemia (AML), acute lymphoblastic leukemia (ALL), chronic myelogenous leukemia (CML), chronic lymphocytic leukemia (CLL), diffuse large B - cell lymphoma (DLBCL), mantle cell lymphoma (MCL), Burkitt's lymphoma, anaplastic large cell lymphoma (ALCL),
cutaneous T - cell lymphoma (CTCL), Hodgkin's lymphoma (nodular sclerosis) and multiple myeloma (MM) cell lines including cells resistant to standard of care (dexamethasone in MM) and
primary samples.
The most common
cutaneous primary sites include mucous membranes of the oral cavity and lips, rectum and the colon, skin of the limbs, head, ears.