Sentences with phrase «profile tumor analysis»
Not exact matches
Nagrath, director of Rice's Laboratory for Systems Biology of Human Diseases, said the new metabolic analysis indicates that ovarian cancer may be susceptible to multidrug cocktails, particularly if the amounts of the drugs can be tailored to match the metabolic profile of a patient's tumor.
https://www.sciencedaily.com/
Utilizing tumors from a genomic analysis clinical trial at Rutgers Cancer Institute examining rare cancers and those that respond poorly to standard care, 97 tumors with the P13K / AKT / mTOR pathway were profiled.
Previously, genetic counselors tested a small number of genes sequentially based on family profile and tumor analysis until the culprit was identified.
Individual profiles based on the analysis of each patient's tumor cells revealed clinically relevant information that could be used to prioritize the drugs most likely to be effective in these cases.
Many of our brain tumor clinical trials include analysis of the molecular profiles of patients» tumors.
In the next decade, molecular research is going to further develop along five lines: predictive medicine, that investigates the genetic conditions predisposing to tumor risk; early molecular diagnosis; the evaluation of each patient's prognosis based on his / her genetic profile, in other words, the analysis of what kind of mutation affects the DNA of altered cells; the investigation of the individual response to drugs, based on our genetic knowledge; «smart drugs», molecules able to hit the target in a selective way, killing only the deprogrammed cells.»
To further confirm the alteration of DDX3 expression in cancer specimens, the expression profiles of DDX3 were examined in normal - tumor paired HCC samples by immunohistochemical staining analysis using specific anti-DDX3 antibody.
Because DDX3 harbors growth - suppressive ability and transcriptional modulation activity of the p21waf1 / cip1 promoter, in this work we further examined the deregulated expression of DDX3 in tumors by a cancer profiling array and immunohistochemical staining analysis.
Our groundbreaking Pediatric Mi - Oncoseq Program is an internationally known precision oncology program focusing on the genetic analysis of pediatric cancer patients including in children with malignant brain tumors, and determines whether targeted treatments may be available based upon their personalized tumor genomic sequencing profiles.