Sentences with phrase «protein nucleic»

Rearrangements in the mtDNA will be monitored by long extension - PCR (LX - PCR) and mtDNA point mutations will be analyzed by direct mtDNA sequencing and by Protein Nucleic Acid (PNA)- competitive PCR (PNA - PCR).

American Academy Of Arts And Sciences, Science, Chemistry, Biology, Proteins, Protein Data Bank, Research Collaboratory for Structural Bioinformatics Protein Data Bank, Bioinformatics, nucleic acids, protein nucleic acid complexes, Collagen, Structural Biology, Macromolecules, Medicine, Health, Rutgers University - New Brunswick, Rutgers, Rutgers School of

Not exact matches

Were there not a certain invariance about the way in which carbon atoms bond with others under identical conditions, or about the manner in which protein synthesis is charted and activated by nucleic acids, life would be impossible altogether.

Nucleotides and amino acids are substances which, there is reason to believe, could have been formed, and polymerized into nucleic acid and protein respectively, under certain conditions on a lifeless earth.

The four major classifications of biological molecules are proteins, carbohydrates, lipids (fats), and nucleic acids (but we won't be dealing with these today).

The new methods allowed them to catch proteins in the act of binding to RNA, and also identify what part of the protein was in contact with the nucleic acid.

That is, they depend on the host cell for the raw materials and energy necessary for nucleic acid synthesis, protein synthesis, processing and transport, and all other biochemical activities that allow the virus to multiply and spread.

Further research by Stanley and others established that a virus consists of nucleic acids (DNA or RNA) enclosed in a protein coat that may also shelter viral proteins involved in infection.

Found in amino acids, the building blocks of proteins; an essential part of the nucleic acids that constitute DNA.

The CRISPR system is made up of two components: a protein called Cas9 and a guide RNA, a string of nucleic acid molecules with a certain genetic code.

Magnetic beads have long been used to isolate nucleic acids as well as recombinant proteins.

However, in the past decade scientists realized that exosomes play important roles in many biological functions through capsuling and delivering molecular messages in the form of nucleic acids and proteins from the donor cells to affect the functions of nearby or distant cells.

The FDA's new requirements would also extend to medically important «biologic» drugs — products composed of sugars, protein or nucleic acids that are typically made from living microorganisms.

Nucleic acid and protein sequences, as well as three - dimensional structures of proteins, are frequently the objects of study, but gene expression as well as the simulation of pathways and biochemical networks are attracting more and more attention.

Most research into life's origins has focused on how organic building blocks, like amino acids and nucleic acids, arose and assembled themselves into proteins and RNA.

They can also deliver precise doses of drugs, nucleic acids, or proteins to targeted points on the cell.

For tumors to grow and spread, cancer cells must make larger than normal amounts of nucleic acids and protein, so they can replicate themselves.

And, given the wide applicability of electrochemical detection to many types of biomolecules, the platform «can be readily extended to the detection of other disease markers such as proteins, metabolites, ions, and nucleic acids,» Liu added.

In the study published in Nucleic Acids Research, the researchers were able to induce and inhibit the expression of genes in mammalian cell cultures and were able to regulate intracellular protein levels using light signals.

This allows us to define in a very broad sense what proteins, nucleic acids, pathogens, and toxins might be part of the milieu of the fetus.

Two projects will be done jointly with the Karolinska Institute in Stockholm: Molecular biologist David Baillie of Simon Fraser University in Burnaby, British Columbia, was awarded $ 6.73 million to study protein function in the soil nematode Caenorhabditis elegans, and microbiologist Sherif Abou Elela of the University of Sherbrooke, Quebec, received $ 3.75 million to test modified nucleic acid technologies for determining gene function.

It also hints at why proteins were eventually preferred by evolution over nucleic acids as catalysts in biology: proteins offer much more ability to «tune» their «jiggling and wiggling» and their response to chemical reactions.

MicroRNAs are short bits of nucleic acid — the material of DNA and RNA — that can bind to messenger RNAs that code for protein because they have a complementary sequence of A, U, C and G.

MicroRNAs are very short bits of nucleic acid — the material of DNA and RNA — that can bind to messenger RNAs that code for protein.

The immune system detects viruses when viral nucleic acids bind protein receptors in immune cells.

The find highlights how ancient viruses can more easily be identified by their proteins than their more commonly studied nucleic acids, such as DNA or RNA.

This realm of research is called epigenetics, and at the heart of it is chromatin — the nucleic acids and proteins that package DNA to fit inside cells.

He won two Nobel Prizes for chemistry, but we claim him for molecular biology because the methods he developed for sequencing proteins and nucleic acids provide the basis for much of what we do today.

Ribonucleic acid or RNA is a nucleic acid polymer consisting of nucleotide monomers that plays several important roles in the processes that translate genetic information from deoxyribonucleic acid (DNA) into protein products;

Joint winner of the 1980 chemistry prize with Walter Gilbert for his «contributions concerning the determination of base sequences in nucleic acids» and winner of the 1958 chemistry prize «for his work on the structure of proteins, especially that of insulin.»

«There's a tradition of trying to hire smart people and then basically leaving them to it,» says Leo James, a group leader in the Protein and Nucleic Acid Chemistry Division.

Winner of the 1982 chemistry prize «for his development of crystallographic electron microscopy and his structural elucidation of biologically important nucleic acid - protein complexes.»

Nanomachines include structures of complex proteins and nucleic acids that are powered with chemical energy and can perform directed movements.

As published this week in Nucleic Acids Research, they have discovered a mechanism that regulates the expression of alpha - synuclein, a protein linked to Parkinson's disease and multiple system atrophy (MSA).

This latter capability is extremely valuable to biomedical research, which relies heavily on fluorescent probes to label and track proteins, nucleic acids, and other cellular components.

Nogales and her team use structural biology to elucidate how biomolecules, particularly proteins and nucleic acids (DNA, RNA), are organized and combine to form functional biological assemblies.

ANA (amyloid nucleic acid) consists of nucleic acids attached to amyloid proteins, infamous for their role in Alzheimer's disease.

This goo links molecules together when heated, stabilizing proteins and nucleic acids to maintain the integrity of the tissue.

Colon cancer cells produce proteins, fatty acids, nucleic acids and reactive oxygen species (ROS).

But it's still a mystery how the amino acid building blocks were first assembled according to coded nucleic acid templates into the proteins that formed the machinery of all cells.

Special computational techniques are also available to discover biological targets (proteins, nucleic acids) of a drug.

Life on Earth originated in an intimate partnership between the nucleic acids (genetic instructions for all organisms) and small proteins called peptides, according to two new papers from biochemists and biologists at the University of North Carolina at Chapel Hill and the University of Auckland.

Nucleic acids and proteins trapped in ancient mummies and still more ancient bones can serve as time capsules of history.

Proteins, fatty acids, and nucleic acids are essential factors for cell survival using glutamine metabolism.

Peptide nucleic acid, a synthetic hybrid of protein and DNA, could form the basis of a new class of drugs — and of artificial life unlike anything found in nature

«We've shown that these oviductosomes are carrying critical molecules that include not only proteins, but also nucleic acids such as RNA and also lipids,» DeLeon says.

The origin of life is not the same as the origin of its constituent building blocks, but laboratory studies on the linking of amino acids into molecules resembling proteins and on the linking of nucleotides into molecules resembling nucleic acids are progressing well.

With his wife, Margaret, Clark then moved to Boston, where he had secured a 3 - year postdoc with Jack Buchanan, a biochemist at the nearby Massachusetts Institute of Technology (MIT) who was investigating the synthesis of nucleic - acid building blocks called purines and of proteins.

Investigations of how short chains of nucleic acids replicate themselves in vitro have even provided clues to primitive genetic codes for translating nucleic acid information into protein information, systems that could have preceded the elaborate machinery of ribosomes and activating enzymes with which cells now manufacture protein.

We know that the master molecules of living organisms on the earth are the proteins and the nucleic acids.