Sentences with phrase «pyruvate metabolism»

The article «Late - onset Caloric Restriction Alters Skeletal Muscle Metabolism by Modulating Pyruvate Metabolism» is published ahead of print in the American Journal of Physiology - Endocrinology and Metabolism.

Not exact matches

In high carbohydrate diet - induced obesity, may decrease the expression of mitochondrial dihydrolipoyl dehydrogenase / DLD in striated muscles, as well as that of selected glucose / pyruvate metabolic enzymes, hence affecting energy expenditure through mitochondrial metabolism (PubMed: 26671069).

Aβ is believed to penetrate neuronal plasma membranes, where it leads to lipid peroxidation.10 It has also been implicated in deactivating a subunit of the pyruvate dehydrogenase complex, thereby inhibiting conversion of pyruvate to acetyl CoA and the eventual production of cellular energy as ATP.32 Another way Aβ affects glucose metabolism in the brain is that fragments of Aβ disrupt insulin signaling by binding to neuronal synapses, which alters their shape and function.15, 38 Insulin receptors are abundant at synapses, so if the integrity of the synapse itself has been compromised, the receptors won't function effectively.

In addition, mercury impairs many enzymes needed to metabolize food into energy, including pyruvate dehydrogenase, which is required for metabolism of carbohydrates but not fats or proteins.

The traditional or modified ketogenic diets should not be used in individuals who have fatty acid oxidation defects, pyruvate carboxylase deficiency, primary carnitine deficiencies, organic acidurias, defects in ketone metabolism, disorders that require high dietary carbohydrates as part of their treatment, severe liver disease or hypoglycaemia under investigation (4).

His main field of work are disorders of brain energy metabolism such as GLUT1 deficiency syndrome or pyruvate dehydrogenase deficiency.

From hyperlipid blog: «The mutation is linked, not surprisingly, to failure to generate ketones in infancy -LSB-...] Three of the seven patients and two cousins had hypoketotic hypoglycemia attributable to CPT - Ia deficiency -LSB-...] if you can't transport LCFAs in to your mitochondria, you should run your metabolism on glucose / pyruvate -LSB-...] This means raw corn starch ``

Pyruvate kinase (PK) deficiency has been found in the breed and glycogen storage disease type IV, an inherited abnormality of glucose metabolism, is also seen in Norwegian Forest cats.