Sentences with phrase «ra activities»

Maintain global oversight of local RA activities in response to local health authority questions regarding assigned projects.

They are working together to mesh her identification of compounds that target tumors with runaway Ras activity and tumor data (analyzed by machine learning) to find patients who could benefit from these potential cancer drugs.

Not exact matches

The RA - Cert dispute evaluation team shall be impartial and independent from the client and the certification and audit activities related to the dispute (e.g., independent from the audit evaluation and certification decision).

Complaint (formal): A written communication of dissatisfaction, other than appeal, by any complainant, relating to the activities of RA - Cert staff / contractors and / or organizations holding an RA - Cert certificate, or verification or validation statement, where a response from RA - Cert is expected.

Complaint (informal): Initial expression of dissatisfaction relating to the activities of RA staff / contractors and / or organizations holding a RA - Cert certificate, or verification or validation statement.

«Rae Grant is a children's book designer and author of several family activities books.

When the researchers analysed the activity in an area of the brain that is important for the production of song — an area known as nucleus RA — they found a clear correlation between its activity pattern and the occurrence of the «stack» call.

Drugs that targeted the RAS pathway showed little activity against the tumor cells.

Researchers did not understand what normally kept ras genes» protein production in check — and why certain ras mutations led to such chaotic, uncontrolled cellular activity — until the discovery of a snippet of genetic material called microRNA (miRNA).

«Our findings show that a specific genetic marker (known as allele * 2 of the HS1, 2 A enhancer region) influences not just disease activity in RA patients, but also response to therapy in the early stages of their disease,» said lead investigator Dr Gabriele Di Sante of the Institute of Rheumatology and Related Sciences, Catholic University of the Sacred Heart, Rome, Italy.

In the new work, Daniel Margoliash and his colleagues at the University of Chicago recorded HVc and RA neuron activities in awake birds.

In collaboration with the University of Texas Southwestern Medical Center (UTSW) in Dallas, the researchers found that the tumor - suppressive activity of geranylgeraniol was accompanied by down - regulation of HMG CoA reductase, a key enzyme in the mevalonate pathway that provides essential intermediates for the posttranslational modification of growth - related proteins such as Ras, nuclear lamins and insulin - like growth factor receptors.

Shokat and his team have designed a chemical compound that fits inside this pocket and inhibits the normal activity of mutant K - Ras, but leaves the normal protein untouched.

Their goal was to establish if systemic genetic inactivation of autophagy would have selective anti-tumor activity against Ras - driven lung cancers while sparing most normal tissues.

«The finding that certain cell signaling lipids change the activity of an oncogenic Ras protein, suggests that we might be able to interfere with tumor progression by inhibiting the enzymes which make the specific cell signaling lipid in cells,» Buck said.

In an open letter last month to President Vladimir Putin, more than 150 RAS researchers asserted that the reforms are eroding science's image in Russia; they warned of disastrous consequences for the nation, including a brain drain of young scientists and an «upsurge in activities of bureaucrats and impostors.»

Drug companies had long ago given up on targeting RAS, however, because it doesn't have an obvious pocket, or binding site, that a drug could fit into to block its activity, says Frank McCormick, who recently stepped down as director of the Helen Diller Family Comprehensive Cancer Center at the University of California, San Francisco, to spend half his time directing NCI's RAS project.

The researchers discovered that DNA methylation — a fundamental, life - long process in which a methyl group is added or removed from the cytosine molecule in DNA to promote or suppress gene activity and expression — does in fact vary between FLS from the knees and hips of RA patients.

Although work - related physical activity over many years is known to cause many cases of osteoarthritis (OA) in selected joints, this is the first study to show a link between physical workload and RA.

The RAS organises scientific meetings, publishes international research and review journals, recognizes outstanding achievements by the award of medals and prizes, maintains an extensive library, supports education through grants and outreach activities and represents UK astronomy nationally and internationally.

The RAS organizes scientific meetings, publishes international research and review journals, recognizes outstanding achievements by the award of medals and prizes, maintains an extensive library, supports education through grants and outreach activities and represents UK astronomy nationally and internationally.

«With emphasis on reaching a targeted low - disease activity state, physicians have many drugs to choose from for treating RA patients including triple therapy.

Deletion of DGKζ from T cells results in prolonged TCR signal transduction downstream of DAG, resulting in enhanced activation of Ras, increased effector T cell proliferation, and amplified cytokine production, which leads to increased antitumor activity against s.c. implanted EL4 tumors or murine mesothelioma (12, 16, 17).

Our data suggests that targeting DGKζ could prove to be a more useful clinical approach to augment cytotoxic T cell activity against tumor than targeting Cbl - b, perhaps resulting from enhanced Ras / ERK signaling.

The findings found increased incidents of RA and GCA to be in periodic concert with the cycle of magnetic activity of the sun.

The basal and B - RAF - stimulated kinase activities of a third variant are unaltered but its activation by RAS is significantly reduced, suggesting that it may act in a dominant - negative manner to modulate pathway signaling.

In the group's initial scan of the tumor samples, researchers identified gene mutations that would increase RTK / RAS / RAF pathway activity in 62 percent of the samples.

The Rho GEFs activate Rho proteins that are part of the RAS superfamily — a class of proteins associated with cancer activity.

RA can make even the simplest activities — opening jars, climbing stairs, putting on clothes — difficult and painful.

Yoga may be a gentle, soothing form of physical activity for someone with RA or a similar disease, but can regular yoga practice actually help reduce inflammation?

As well as the adventure and activity products offered throughout the Hajar mountain range, Ras Al Khaimah offers over 7,000 years of history and is home to ancient archaeological sites such as the Dhayra Fort and the ancient village of Al Jazira Al Hamra, as well as 64 kilometres of pristine beaches and world class hotels.

Visitors to Ras Al Khaimah will enjoy idyllic sojourns on terracotta beaches and resorts, adventure activities including water sports, micro-lighting, mountain climbing and kayaking, as well as an eclectic selection of international gourmet experiences and world - class spas set to genuine Arabian ambiance and hospitality.

If you're looking to enjoy an adventurous holiday in the United Arab Emirates, Ras al Khaimah has a wide range of activities to keep you energised during your vacation.

Perform lots of activities such as go for hiking and swimming in the countryside or bath in the mesmerizing waterfalls like Ras El Maa.

Each pack includes a sketchbook to use during your visit to the RA and at home, as well as a pack of cards bursting with drawing activities and information about artworks in the exhibition.

From renowned exhibitions, public debates and artists» gatherings to stylish social events and life in the RA Schools, the artwork reveals the rich tapestry of activity at the Academy.

Come and experience art, music, cocktails, mermaid life drawing, performance art, tropical funk DJs, craft activities, talks and more at the RA's end of summer party on Piccadilly.

Zoffany's painting tells us that life drawing, and discussion about it, has been at the core of the RA's activities, a notion explored in depth in the Academy's new exhibition From Life.

Download our bespoke teacher resources to know more about an exhibition and get ideas for activities for your students before, during or after your visit to the RA.

Complaint (formal): A written communication of dissatisfaction, other than appeal, by any complainant, relating to the activities of RA - Cert staff / contractors and / or organizations holding an RA - Cert certificate, or verification or validation statement, where a response from RA - Cert is expected.

Complaint (informal): Initial expression of dissatisfaction relating to the activities of RA staff / contractors and / or organizations holding a RA - Cert certificate, or verification or validation statement.

2007/04/20: SciDaily: Astronomer Backs Link Between Greenhouse Gases And Climate Change Professor Nigel Weiss, 2007 winner of the Royal Astronomical Society (RAS) Gold medal, is rebutting claims that a fall in solar activity could cancel out the effects of man - made global warming.

Consistently making decisions to engage and actually engaging in business development activity will also stimulate your RAS in a similar way, but, unfortunately, especially in the early stages, lawyers aren't very consistent with their activity.

Writing down your business development activity will cause your RAS to prioritize information relating to your business development activity and you will start to notice more things that are connected to it — more ideas, more opportunities, more things that will help you improve your business development competency.

Manage procurement, development, and maintenance of IT activities, including file and print servers, application services, active directory objects, and GPO, LAN, WAN, and RAS access.

SUMMARY OF QUALIFICATIONS • Six years of RA experience with the University of Tucson, Arizona • Highly experienced in maintaining a liaison between the residents and administration • In - depth knowledge of the several and individual needs of residents and how best to look after them • Hands - on experience in creating and implementing social and recreational activities for the residents

EXTRA CURRICULAR ACTIVITIES • Member of the college music club • Performed RA duties in various subjects • Editor of the school yearbook and newspaper

Adult Nurse Practitioner — Duties & Responsibilities Provide exceptional patient care and medical team support across multiple medical specialties Currently completing clinical and academic work toward a master of science in nursing Utilize strong background in biology, chemistry and mathematics Maintain working knowledge of current medical technology, procedures, and standards of care Proven ability to remain calm and levelheaded in high pressure situations Direct therapeutic, educational, and recreational activities for eight developmentally disabled adults Responsible for patient health, safety, and attainment of therapy goals Train and supervise medical lab personnel ensuring efficient and professional operations Offer guidance and support to junior lab technicians and medical technologists Perform a wide variety of daily testing utilizing machines such as AXSYM — Hitachi RA 1000 CX 7 Responsible for preventative maintenance on machines by running calibrations and controls Successfully complete monthly state proficiency tests for therapeutic drug, blood, and urine chemistries Prioritize stat specimens for immediate reporting Maintain direct contact with clients to resolve problems regarding appropriate tests and specimens Oversee confidential patient information, customer service, phones, and other administrative functions as needed Perform all duties in a positive, professional, and courteous manner