Our approach is innovative in that we propose to study a novel group of bioinformatically - predicted factors, which we hypothesize cooperate in controlling
RGC axon growth and regeneration.
Not exact matches
We will leverage state - of - the - art bioinformatic and biological approaches for investigating how these factors interact in combination to regulate
axon growth during
RGC development and test the potential of such factors for regenerating
RGC axons in a rodent model of optic nerve injury.
Identifying factors that regulate directional
growth of regenerating
RGC axons to their targets will provide invaluable information on developing future therapies to repair degenerated optic nerve following glaucoma.