Sentences with phrase «rna as a biomarker»
«Triple - negative breast cancer continues to be a severe health problem, demanding the consideration of emerging long non-coding RNAs as biomarkers and therapeutic targets in combatting this disease,» said Liquing Yang, Ph.D., assistant professor in the Department of Molecular & Cellular Oncology.
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Nucleic acids are also helping scientists to detect biomarkers, such as Abcam's Fireplex (formerly Firefly) particle technology, which profiles biomarker microRNAs (miRNAs) directly from biofluid samples, without RNA purification.
«These results highlight RNA editing as an exciting theme for investigating cancer mechanisms, biomarkers and treatments,» said Han Liang, Ph.D., associate professor of Bioinformatics and Computational Biology.
The larger scale Cancer Genome Atlas study provided the information needed to alter proteins or RNA sequences that may act as «drivers» for prognostic biomarkers or therapeutic targets.
The high expression specificity of SHOT - RNAs implies their potential use as a novel biomarker, and the next steps, says Dr. Kirino, are to explore relationships between SHOT - RNA expression and prognostic factors.
Research on vaccine biomarkers, including in - depth comparative analysis of data from different platforms, large - scale RNA sequencing, harmonisation of standard operating procedures (SOPs) for sample, microarray and data analysis, as well as transcriptome mapping (more than 1400 samples analysed).