The PR - 2B DENV - 2 produced increased levels of subgenomic flavivirus RNA (sfRNA) relative to genomic
RNA during replication.
Not exact matches
This is because
during replication, DNA polymerase can only synthesize DNA in a 5 «to 3 «direction and can only do so by adding polynucleotides to an
RNA primer that has already been placed at various points along the length of the DNA.
It has multiple hosts and can evolve by mutation but also reassortment (when two closely related strains infect the same host and exchange gene segments, producing new strains — a process distinct from mutation, when the
RNA of a virus is miscoded
during replication).
In a September paper in the Journal of Chemical Physics, he reported the theoretical minimum amount of dissipation that can occur
during the self -
replication of
RNA molecules and bacterial cells, and showed that it is very close to the actual amounts these systems dissipate when replicating.